4-Day Spain Self-Drive Road Trip With Itinerary from Santander traveling east to Bilbao

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Escape the ordinary with this exciting 4-day road trip through Spain. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in Spain takes you through some of the best places to see in the country. You will spend 2 nights in Santander and 1 night in Bilbao. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Spain. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Santander, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Spain on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Spain. Guggenheim Museum and Vizcaya Bridge are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Palacio De La Magdalena, learn more about the unique Centro Botin, and immerse yourself in the vibrant atmosphere of Urdaibai Biosferaren Erreserba.

As you hit the open road and drive through Cueto, Santander, Bilbao, Sukarrieta, and Portugalete, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Spain. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Spain.

Throughout your road trip in Spain, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Spain.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Spain fill up quickly, so book your spot early. Select a date and start planning your road trip in Spain today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Llamas Park
Plaza PorticadaMercado del EsteBotin CentreMuseo Marítimo del CantábricoPalacio de la Magdalena
ZubizuriGuggenheim MuseumDoña Casilda Iturrizar parkUrdaibai Biosphere ReserveVizcaya Bridge
Parque de Mataleñas

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Day 1

Day 1

  • Santander - Arrival day
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  • Llamas Park
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Say hello to Santander! Your exciting road trip through Spain is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Santander for 1 night before you continue your adventure!

Santander is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Llamas Park, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Santander. Check-in typically starts around 2 to 4 PM at hotels in Spain. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Santander, it's often a good idea to reserve a table in advance.

Dine in style at Restaurante la Mayor, a top recommendation for dinner tonight. Or, for a change of pace, Santa & Co boasts a menu that's sure to impress. Also, be sure to check out Marcello Restaurante. Known as a local hotspot, it’s a great choice for tonight in Santander.

Round off your dining experience by visiting Kings Pub, a prime location for a drink. Alternatively, explore the distinctive characteristics of Grog, a bar catering to every mood and preference. Hygge Cocktail likewise offers a unique atmosphere, perfect for a memorable night out.

Raise a toast to the start of your 4-day road trip in Spain!

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Day 2

Day 2

  • Santander
  • Bilbao
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Drive 109 km, 1 hour 47 min

  • Plaza Porticada
  • Mercado del Este
  • Botin Centre
  • Museo Marítimo del Cantábrico
  • Palacio de la Magdalena
  • More

Experience an unparalleled adventure on day 2 of your road trip in Spain. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Santander. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Bilbao. You will spend 1 night here for some well-deserved relaxation.

Today’s itinerary in Santander covers several incredible sights, including a public square, a market, an art gallery, a maritime museum, a palace and much more! Start your adventure at Plaza Porticada. This curiosity-inducing public square is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the historic wonders of Mercado Del Este, a must-see market in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Centro Botin. This locally renowned art gallery offers an enriching experience. For a change of pace, head to Museo Marítimo Del Cantábrico, where you can take in picture-perfect features. Conclude your self-guided sightseeing tour with a visit to Palacio De La Magdalena and Palacio De La Magdalena. These sights offer a fulfilling end to a perfect day.

When you’re done exploring for the day, you’ll drive to your hotel in Bilbao. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Bilbao. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Begin your culinary exploration in Bilbao by securing a reservation at Mina. This renowned restaurant holds 1 Michelin star and offers an exceptional menu of creative and seasonal cuisine. For another dining delight, visit Zortziko, celebrated for its delectable contemporary menu. This acclaimed 1-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Etxanobe Atelier, a top local spot known for its tantalizing creative menu. With a 1-star Michelin recognition, it guarantees an exceptional dining adventure.

Unwind after your meal by stepping into Boss Bilbao. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Stromboli Taberna offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Zuberoa Taberna, another top-rated bar in the area.

Take some time to reflect on your day and savor another beautiful night in Spain.

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Day 3

Day 3

  • Bilbao
  • Santander
  • More

Drive 187 km, 3 hours 17 min

  • Zubizuri
  • Guggenheim Museum
  • Doña Casilda Iturrizar park
  • Urdaibai Biosphere Reserve
  • Vizcaya Bridge
  • More

Embark on another extraordinary experience on day 3 of your road trip in Spain. Today, you will make 3 stops and experience some of the highlights of Bilbao, Sukarrieta, and Portugalete. At the end of the day, you will enjoy the comforts of a top-rated hotel in Santander, which will be your home away from home for 1 night.

Zubizuri is must-visit art installation and a great starting point for the day. Next, continue your journey to Guggenheim Museum, an astonishing museum building, located just a leisurely stroll away.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Bilbao. If you’re looking for more, Urdaibai Biosferaren Erreserba is also a well-known attraction that is worthwhile a visit. Lastly, don’t miss Vizcaya Bridge, a popular gem to see in the city.

At the end of the day, you will drive to Santander, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Santander's best restaurants.

Experience a taste of local culinary excellence while in Santander by securing a table at Cadelo. An esteemed Bib Gourmand restaurant, it features an exceptional modern menu. For an alternative taste experience, visit Umma, famous for its scrumptious modern dishes. This Bib Gourmand venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover Agua Salada, a local favorite celebrated for its exquisite contemporary and traditional cuisine in Santander. Located in the heart of the city, this Bib Gourmand-awardee is an ideal pick for contemporary and traditional cuisine lovers seeking top-notch culinary experiences.

Cap off your dinner by heading to Little Bobby, ideal for a leisurely evening with a drink in hand.

Relax and reminisce about your day in Spain and look forward to more memorable moments to come!

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Day 4

Day 4

  • Santander - Departure day
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  • Parque de Mataleñas
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Day 4 of your road trip in Spain is your departure day. This is your chance to catch a last glimpse of Santander before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Parque De Mataleñas. This often recommended park is a popular place to see in the city.

Make the most of your final day in Spain by visiting Santander’s iconic markets and shopping establishments in the buzzing El Corte Inglés. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Spain.

Before you conclude your road trip in Spain, drop by another restaurant for a last chance at a memorable dining experience in Santander.

You’ll then say farewell to Santander. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Spain!

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