6-Day Spain Self-Drive Road Trip With Itinerary from Santander traveling south to Valladolid and Bilbao

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Explore the best of Spain on a 6-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Santander, Cueto, Valladolid, Segovia, Burgos Province, Portugalete, Bilbao, Villaescusa, and Rionansa. This road trip itinerary in Spain seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Spain takes you through some of the best places to see in the country. You will spend 2 nights in Santander, 2 nights in Valladolid, and 1 night in Bilbao. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Spain. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Santander, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Spain on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Spain. Aqueduct Of Segovia and Guggenheim Museum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Alcázar Of Segovia, learn more about the unique Cabarceno Natural Park, and immerse yourself in the vibrant atmosphere of Burgos Cathedral.

As you hit the open road and drive through Santander, Cueto, Valladolid, Segovia, Burgos Province, Portugalete, Bilbao, Villaescusa, and Rionansa, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Spain. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Spain.

Throughout your road trip in Spain, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Spain.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Spain fill up quickly, so book your spot early. Select a date and start planning your road trip in Spain today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Plaza Porticada
Botin CentreMuseo Marítimo del CantábricoPalacio de la MagdalenaCentro de Arte Faro Cabo Mayor
Aqueduct of SegoviaSegovia CathedralAlcázar of SegoviaParque Campo Grande
Puente de Santa MaríaArco de Santa MaríaBurgos CathedralVizcaya Bridge
Federiko Moiua enparantzaPuppyGuggenheim MuseumCabarceno Natural ParkCueva El Soplao
Llamas Park

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Day 1

Day 1

  • Santander - Arrival day
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  • Plaza Porticada
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Welcome to Santander, the perfect starting point for your road trip in Spain! Pick up your rental car and let the adventure begin. You will spend 1 night immersing yourself in Santander's charm before embarking on the next leg of your journey.

Santander is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Plaza Porticada, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Santander. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Spain. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Santander, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Restaurante la Mayor, a top-rated dining destination in Santander. If you're in the mood to try something new, consider Santa & Co, another top spot with a mouthwatering menu. You might also want to secure a reservation at Marcello Restaurante. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Santander this evening.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Kings Pub, known for its inviting atmosphere. Grog is another great option if you’re looking for a place to get the night started. Similarly, Hygge Cocktail provides a great setting to enjoy the night away.

Raise a toast to the start of your 6-day road trip in Spain!

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Day 2

Day 2

  • Santander
  • Valladolid
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Drive 259 km, 3 hours 8 min

  • Botin Centre
  • Museo Marítimo del Cantábrico
  • Palacio de la Magdalena
  • Centro de Arte Faro Cabo Mayor
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On day 2 of your exciting self-drive vacation in Spain, you’ll soak in the magnificence of 2 destinations, Santander and Cueto. When you’re not sightseeing, take time to relax at your selected hotel in Valladolid, where you’ll be staying for 2 nights.

Immerse yourself in Santander’s rich culture with today's sightseeing itinerary. Start your journey at Centro Botin. This eye-catching art gallery is sure to ignite your curiosity. Next, dive into the gorgeous features of Museo Marítimo Del Cantábrico, a must-visit maritime museum in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Palacio De La Magdalena, a captivating palace. For a change of scene, check out Centro De Arte Faro Cabo Mayor, known for its visually striking features.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Valladolid. Valladolid offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Valladolid. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a memorable dining experience in Valladolid by booking a table at Llantén, renowned as a Bib Gourmand restaurant presenting an exceptional traditional menu. For a different culinary experience in Valladolid, Alquimia - Laboratorio shines as one of the top destinations, known for its delicious creative and modern cuisine. This 1-star Michelin-awardee earns consistently high praises from previous guests, making it a must-visit addition to your holiday experience. If you're looking for an alternative, Trigo is known as a top local spot for its delicious modern cuisine in Valladolid. This 1-star Michelin awardee is a highly recommended choice for an unforgettable meal.

If you’re not ready to end the night just yet, Bar Panoramix offers a perfect venue to relax and savor a drink. Similarly, Bar Esgueva is well-suited for those looking to unwind in a social setting. Largo Adiós is another excellent spot to enjoy a nightcap after a delightful meal.

Raise your glass to another unforgettable day in Spain!

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Day 3

Day 3

  • Valladolid
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Drive 232 km, 3 hours 4 min

  • Aqueduct of Segovia
  • Segovia Cathedral
  • Alcázar of Segovia
  • Parque Campo Grande
  • More

On day 3 of your road trip, you’ll start and end your day in Valladolid, where you'll stay for 1 night more.

Get ready for an exciting day in Valladolid. Today’s sightseeing agenda includes a monument, a church, a castle, a park and much more! Begin your adventure at Aqueduct Of Segovia. This is an iconic monument you should not miss. Another must-see is Segovia Cathedral, a popular church in Valladolid.

When you’re ready for the next sight, head to Alcázar Of Segovia. From there, take a leisurely stroll to Parque Campo Grande, another of the city’s popular attractions.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Valladolid.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Valladolid. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a lovely dining experience at Sercotel Valladolid, a popular restaurant in Valladolid. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Valladolid at Café & copas Murmullo, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated ATYPIKAL. It’s yet another ideal choice to enhance your time in Valladolid tonight.

Explore the vibrant nightlife at The Lost Child Cocktail's Bar after your meal, a hub for lively evenings and memorable moments. Or, head to Café Bar Alborada for a great selection of flavorful drinks and a charming setting. Furthermore, Monasterio is perfect for those looking to extend their night with a touch of local flavor.

Raise your glass to another unforgettable day in Spain!

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Day 4

Day 4

  • Valladolid
  • Bilbao
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Drive 311 km, 3 hours 46 min

  • Puente de Santa María
  • Arco de Santa María
  • Burgos Cathedral
  • Vizcaya Bridge
  • More

Embark on another extraordinary experience on day 4 of your road trip in Spain. Today, you will make 2 stops and experience some of the highlights of Burgos Province and Portugalete. At the end of the day, you will enjoy the comforts of a top-rated hotel in Bilbao, which will be your home away from home for 1 night.

Today, you'll explore some of the most beautiful places in Valladolid, including a monument and a church. Start your day with a visit to Puente De Santa María. This underrated monument is a must-visit in the city. When you’re ready for your next discovery, continue to Arco De Santa María, which may be one of the most picture-perfect places you will experience today.

One of the best things about exploring Valladolid on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Burgos Cathedral, a popular church in the city. If you’re up for more discoveries, don’t forget to reserve some time for Vizcaya Bridge.

When you’re done exploring for the day, you’ll drive to your hotel in Bilbao. Check in and spend some time relaxing before you head out to tour the city.

Indulge in a memorable dining experience at one of Bilbao's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to an extraordinary dining experience at Mina, a 1-star Michelin restaurant offering an incredible creative and seasonal menu. Alternatively, if your taste buds call for something different, Zortziko is one of the best restaurants for contemporary cuisine in Bilbao. This 1-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at Etxanobe Atelier. As a top-rated establishment with 1 Michelin star, it is an ideal choice for creative cuisine in the city.

Keep the excitement of the evening going by visiting a bar or two. Boss Bilbao is an excellent place to start. You could also check out Stromboli Taberna, offering a different kind of charm. A last recommendation for the day is Zuberoa Taberna. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Head back to your accommodation in Bilbao and get some rest in preparation for another magical day of your road trip in Spain!

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Day 5

Day 5

  • Bilbao
  • Santander
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Drive 234 km, 3 hours 18 min

  • Federiko Moiua enparantza
  • Puppy
  • Guggenheim Museum
  • Cabarceno Natural Park
  • Cueva El Soplao
  • More

On day 5 of your road trip in Spain, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Bilbao, Villaescusa, and Rionansa. In the evening, you’ll end up in Santander, where you will stay for 1 night.

Start your adventure at Federico Moyúa Enparantza. This locally appreciated point of interest is a must-visit for travelers looking for a unique holiday experience. Make your way to Puppy located in Bilbao for an enchanting atmosphere.

Next, immerse yourself in the setting of Guggenheim Museum. After the museum building, continue your tour of the city with a visit to Cabarceno Natural Park. This safari park has a peaceful appeal. For a change of pace, head to Cueva El Soplao. As one of the most notable attractions in Bilbao, this sightseeing destination is an excellent place to end your self-guided tour.

At the end of the day, you will drive to Santander, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Santander's best restaurants.

Experience a harmony of flavors at Cadelo in Santander by securing a reservation in advance. Known for its Bib Gourmand status, Cadelo offers a delightful variety of dishes highlighting its delicious modern menu. If you're seeking an alternative culinary experience, be sure to explore Umma, a highly recommended restaurant known for its enticing modern cuisine. This popular Bib Gourmand-awarded venue consistently exceeds expectations, ensuring a memorable holiday experience. Ready for another culinary adventure? Indulge your senses at Agua Salada, a highly acclaimed restaurant celebrated for its exceptional contemporary and traditional menu.

Explore the vibrant nightlife at Little Bobby after your meal, a hub for lively evenings and memorable moments.

Raise your glass and celebrate another amazing day of your road trip in Spain!

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Day 6

Day 6

  • Santander - Departure day
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  • Llamas Park
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Day 6 of your road trip in Spain is your departure day. This is your chance to catch a last glimpse of Santander before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Llamas Park, an enchanting park before you head out.

Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in Spain, drop by another restaurant for a last chance at a memorable dining experience in Santander.

If you're in the mood to try something new, consider El Sol, another top spot with a mouthwatering menu.

You’ll then say farewell to Santander. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Spain!

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