6-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling south to Trikala

Day 2 of your road trip will take you to the best attractions Thessaloniki has to offer. Cherish the 2 nights you have left in Thessaloniki by discovering the best things there are to see and do in the city.

Don’t miss Tsimiski Street in Thessaloniki today, a must-see street that offers a glimpse into the city’s vibrant character. Take your time to explore its best features, and enjoy the convenience of nearby top-rated landmarks.

Today's adventure in Thessaloniki promises more breathtaking discoveries and enriching experiences! Begin at Heptapyrgion Of Thessaloniki. This culturally significant castle is a highlight of any visit in the city. Then, enjoy Atatürk Museum, another heritage-rich attraction that never fails to captivate visitors. Next, head over to Holy Church Of Saint Demetrius, Patron Saint Of Thessalonica, one of the city’s most up-and-coming attractions, known for its heritage-rich features.

If you’re looking for more, spend time soaking in the atmosphere of Aristotelous Square. This history-steeped public square is frequented by locals and tourists alike. To complete your memorable day, make sure to take a stroll around the area.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Greece is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Indulge in a memorable dining experience at one of Thessaloniki's most popular restaurants, and connect with friendly locals for an authentic adventure.

Make sure to reserve a table at Mamalouka, an iconic dining spot in Thessaloniki. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Clochard, a popular restaurant in Thessaloniki. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Sofi's House Restaurant, a hidden gem nestled in Thessaloniki. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

If you’re not ready to end the night just yet, Castra- All Day Terrace Bar offers a perfect venue to relax and savor a drink. Similarly, Barbaben - Bar/ba/ben is well-suited for those looking to unwind in a social setting. Apallou is another excellent spot to enjoy a nightcap after a delightful meal.

Savor another day of unforgettable experiences in Greece!

On day 3 of your road trip, you’ll start and end your day in Thessaloniki, where you'll stay for 1 night more.

Savor the day by visiting some of the best places to see in Thessaloniki, including a market, a public square, a monument, a waterfall and much more! Start your adventure at Kapani. This locally renowned market is a must-visit for travelers looking for a unique holiday experience. Make your way to Agias Sofias Square located in Thessaloniki for another exciting encounter.

Next, immerse yourself in the setting of Arch Of Galerius And Rotunda. Its standout features will captivate you. After the monument, continue your tour of the city with a visit to White Tower Of Thessaloniki. Visitors usually appreciate the picture-perfect features of this monument. Next up is Waterfalls Park, Edessa, a highly recommended waterfall.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Thessaloniki.

As you explore more of Thessaloniki, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Make sure to reserve a table at Enoches Bar, an iconic dining spot in Thessaloniki. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of O Loytros, a popular restaurant in Thessaloniki. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of rOOTS, a hidden gem nestled in Thessaloniki. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Explore the vibrant nightlife at Peiratis Cafe-bar after your meal, a hub for lively evenings and memorable moments. Or, head to In Rock Cafe Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Tribeca is perfect for those looking to extend their night with a touch of local flavor.

Savor another day of unforgettable experiences in Greece!

On day 4 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 2 destinations, Trikala and Kato Palaiokarya. When you’re not sightseeing, take time to relax at your selected hotel in Trikala, where you’ll be staying for 1 night.

Enjoy the perfect balance of relaxation and exploration in Thessaloniki today. One of the most frequently visited attractions included on the itinerary is Byzantine Castle Of Trikala. This enchanting castle will help you start your sightseeing on top. Then, take a leisurely stroll to Matsopoulos Park and learn what makes this instagrammable park unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the up-and-coming Stone Bridge And Waterfall Of Palaiokarya. After exploring the waterfall, head to Central Bridge. This underrated public square is a highlight in Thessaloniki. As your day continues, stop by Trikala City Center Square, known for its enchanting features.

When you’re done exploring for the day, you’ll drive to your hotel in Trikala. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Trikala. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Dine in style at ALVEO, a top recommendation for dinner tonight. Or, for a change of pace, Trikala Fortress boasts a menu that's sure to impress. Also, be sure to check out Palia Istoria. Known as a local hotspot, it’s a great choice for tonight in Trikala.

Keep the evening going at Soyita Art Cafe, a great choice for enjoying the after-dinner hours with a drink. You could also go to Factory Café, which offers a similarly pleasant setting and great drinks. Another option is The Love Shake, which provides an inviting environment for unwinding after a busy day out.

Relax and reminisce about your day in Greece and look forward to more memorable moments to come!

Dive into day 5 of your remarkable road trip in Greece. Today you will explore Kastraki, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Thessaloniki. You’ll stay here for 1 night.

Today's adventure in Trikala promises more breathtaking discoveries and enriching experiences! Begin at Meteora. This UNESCO world heritage-listed monastery is a highlight of any visit in the village. Then, enjoy Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour, another picture-perfect attraction that never fails to captivate visitors. Next, head over to Monastery Of Varlaam, one of the village’s most often recommended attractions, known for its historic features.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Thessaloniki. Thessaloniki offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Thessaloniki's best restaurants.

Treat yourself to a delicious dinner at Millet, an excellent option for tonight's dining. Looking for something different? Agora Ouzeri offers a tantalizing alternative with its diverse menu. And don’t miss Oinohoos. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Thessaloniki.

If you’re not ready to end the night just yet, Note Bar offers a perfect venue to relax and savor a drink. Similarly, Kafodeio Greek is well-suited for those looking to unwind in a social setting. Crowbar is another excellent spot to enjoy a nightcap after a delightful meal.

Raise your glass to another unforgettable day in Greece!