10-Day Italy Self-Drive Road Trip With Itinerary from Naples traveling north to Viterbo, Florence, Perugia, and Rome

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Experience the freedom of the open road in Italy as you embark on an unforgettable 10-day road trip! This experience caters to every traveler, featuring destinations like Naples, Tivoli, Viterbo, Siena, Florence, Pisa, Perugia, and Rome.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Naples, 1 night in Viterbo, 2 nights in Florence, 1 night in Perugia, and 2 nights in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Naples, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.

As you hit the open road and drive through Naples, Tivoli, Viterbo, Siena, Florence, Pisa, Perugia, and Rome, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
piazza del Plebiscito
Castel Sant'ElmoChiesa del Gesù NuovoCappella SanseveroNaples National Archaeological Museum
Castel NuovoHadrian's Villa
piazza del CampoSiena CathedralBasilica of San DomenicoFortezza Medicea
Leaning Tower of PisaPiazza del Duomo, PisaPisa CathedralCentral MarketCathedral of Santa Maria del Fiore
piazza della SignoriaUffizi GalleryPonte Vecchiopiazzale Michelangelo

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Day 1

Day 1

  • Naples - Arrival day
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  • piazza del Plebiscito
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Say hello to Naples! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Naples for 2 nights before you continue your adventure!

Naples is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Piazza Del Plebiscito, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Naples. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Naples, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at L'Oca Nera Irish Pub, an excellent option for tonight's dining. Looking for something different? Mimì alla Ferrovia offers a tantalizing alternative with its diverse menu. And don’t miss Spuzzulè Winebar. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Naples.

Keep the evening going at Happening Cocktail Bar, a great choice for enjoying the after-dinner hours with a drink. You could also go to Shanti Art Musik Bar, which offers a similarly pleasant setting and great drinks. Another option is Gran Caffè Gambrinus, which provides an inviting environment for unwinding after a busy day out.

Raise a toast to the start of your 10-day road trip in Italy!

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Day 2

Day 2

  • Naples
  • More

Drive 8 km, 1 hour 32 min

  • Castel Sant'Elmo
  • Chiesa del Gesù Nuovo
  • Cappella Sansevero
  • Naples National Archaeological Museum
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Day 2 of your road trip will take you to the best attractions Naples has to offer. Cherish the 1 night you have left in Naples by discovering the best things there are to see and do in the city.

A blend of fun adventures, breathtaking views, and photo-friendly spots await you in Naples on today’s itinerary. First up is the locally renowned castle, Castel Sant'elmo. Afterward, continue to Chiesa Del Gesù Nuovo, a church every traveler should visit.

As you explore Naples’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Cappella Sansevero. This notable museum is an essential stop. Following that, head to Naples National Archaeological Museum, another must-visit site that will enhance your experience.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Naples's best restaurants.

Discover the culinary delights of Naples by securing a reservation at Veritas. Esteemed for its 1-star Guide Michelin recognition, this restaurant offers a remarkable selection of campanian and contemporary cuisine. For an alternative dining experience, try Il Comandante, renowned for its delicious creative and mediterranean dishes. This esteemed 1-star Michelin-recipient consistently impresses guests, making it a must-visit spot during your holiday. Craving more culinary excitement? Head to ARIA, a highly recommended local eatery celebrated for its mouthwatering contemporary and modern menu. With its 1-star Michelin recognition, it offers an unforgettable dining adventure.

Continue your evening by exploring the vibrant nightlife scene at Archivio Storico - Cocktail Bar & Wonderfood, a prime destination for a thrilling night out. Also, don’t forget to check out Archeobar, a bar that offers unique local touches. Likewise, Babette Pub provides an excellent alternative for a fun evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

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Day 3

Day 3

  • Naples
  • Viterbo
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Drive 318 km, 3 hours 42 min

  • Castel Nuovo
  • Hadrian's Villa
  • More

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Naples and Tivoli. When you’re not sightseeing, take time to relax at your selected hotel in Viterbo, where you’ll be staying for 1 night.

Immerse yourself in Naples’s rich culture with today's sightseeing itinerary. Start your journey at Castel Nuovo. This picture-perfect castle is sure to ignite your curiosity. Next, dive into the UNESCO world heritage-designated features of Hadrian's Villa, a must-visit archeological site in the city.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Viterbo. Viterbo offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Viterbo. Enjoy a satisfying meal that will recharge you for tonight's adventures.

With its reputation for pleasing customers, it’s a fantastic choice for tonight in Viterbo.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 4

Day 4

  • Viterbo
  • Florence
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Drive 251 km, 3 hours 47 min

  • piazza del Campo
  • Siena Cathedral
  • Basilica of San Domenico
  • Fortezza Medicea
  • More

Dive into day 4 of your remarkable road trip in Italy. Today you will explore Siena, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Florence. You’ll stay here for 2 nights.

Today’s agenda in Viterbo includes a public square, a church, and a monument. Piazza Del Campo is must-visit public square and a great starting point for the day. Next, continue your journey to Siena Cathedral, a well-known church, located just a leisurely stroll away. Next, head to Basilica Of San Domenico, a historic church, also available for your discovery today.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Experience a harmony of flavors at Enoteca Pinchiorri in Florence by securing a reservation in advance. Known for its 3-star Michelin status, Enoteca Pinchiorri offers a delightful variety of dishes highlighting its delicious italian contemporary menu. If you're seeking an alternative culinary experience, be sure to explore Santa Elisabetta, a highly recommended restaurant known for its enticing creative and mediterranean cuisine. This popular 2-star Michelin-awarded venue consistently exceeds expectations, ensuring a memorable holiday experience. Ready for another culinary adventure? Indulge your senses at Gucci Osteria da Massimo Bottura, a highly acclaimed restaurant celebrated for its exceptional italian contemporary and international menu.

Round off your dining experience by visiting Manifattura, a prime location for a drink. Alternatively, explore the distinctive characteristics of Se·sto On Arno Rooftop Bar, a bar catering to every mood and preference. Il Vinile likewise offers a unique atmosphere, perfect for a memorable night out.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 5

Day 5

  • Florence
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Drive 174 km, 2 hours 54 min

  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Pisa Cathedral
  • Central Market
  • Cathedral of Santa Maria del Fiore
  • More

Wake up to day 5 of your extraordinary road trip in Italy. With 1 night left in Florence, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Get ready for a day filled with family-friendly attractions, scenic views, and picturesque spots in the charming city of Florence. Your adventure starts at Leaning Tower Of Pisa, an iconic local hot spot. Another notable attraction to explore is Piazza Del Duomo, Pisa. This world-famous public square is known for its remarkable appeal.

After soaking in the highlights of these sights, take some time to wander Florence's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Pisa Cathedral. This UNESCO world heritage-designated church offers a fascinating experience that many visitors find memorable. Central Market is also worth visiting, along with Cathedral Of Santa Maria Del Fiore. These standout landmarks offer unique experiences that add to the day’s enjoyment.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Ditta Artigianale, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Trattoria Da Burde, another top spot with a mouthwatering menu. You might also want to secure a reservation at Casa Toscana. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

After enjoying a fulfilling meal, continue your evening at Bar 50 Rosso, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Bitter Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Archea Brewery provides an excellent environment for a relaxed and enjoyable evening.

Savor another day of unforgettable experiences in Italy!

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Day 6

Day 6

  • Florence
  • Perugia
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Drive 153 km, 2 hours 24 min

  • piazza della Signoria
  • Uffizi Gallery
  • Ponte Vecchio
  • piazzale Michelangelo
  • More

On day 6 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Florence. In the evening, you’ll end up in Perugia, where you will stay for 1 night.

Set out on a day brimming with fun adventures, romantic experiences, and scenic views. Start at the astonishing Piazza Della Signoria, a history-steeped public square in Florence. Next, go to Uffizi Gallery.

After visiting Piazza Della Signoria and Uffizi Gallery, have a stroll along Florence's streets and take in the local charm. Continue your sightseeing by heading to Ponte Vecchio. This visually striking historical landmark offers a unique experience. Piazzale Michelangelo is another noteworthy attraction worthwhile a visit.

At the end of the day, you will drive to Perugia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Perugia. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Ristorante Settimo Sigillo, a highly-rated dining destination in Perugia. If you're eager to try something different, consider Caffè Baglioni, another top spot with a tantalizing menu. You might also want to secure a reservation at Bar Pellas. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Perugia this evening.

To truly maximize your evening out, consider visiting Tommi Bar after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Valentina, another bar with an inviting ambiance. Similarly, Caffe Dal Perugino also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 7

Day 7

  • Perugia
  • Rome
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Drive 184 km, 3 hours

  • Vatican Museums
  • Saint Peter's Square
  • Sistine Chapel
  • St Peter's Basilica
  • More

Embark on another extraordinary experience on day 7 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Vatican City. At the end of the day, you will enjoy the comforts of a top-rated hotel in Rome, which will be your home away from home for 2 nights.

Begin your adventure at Vatican Museums. This is a timeless art museum you should not miss. Another must-see is Saint Peter's Square, an interesting square in Perugia.

When you’re ready for the next sight, head to Sistine Chapel. From there, take a leisurely stroll to St. Peter's Basilica, another of the city’s timeless attractions.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to an extraordinary dining experience at La Pergola, a 3-star Michelin restaurant offering an incredible mediterranean and contemporary menu. Alternatively, if your taste buds call for something different, Il Pagliaccio is one of the best restaurants for creative and innovative cuisine in Rome. This 2-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at Enoteca La Torre. As a top-rated establishment with 2 Michelin star, it is an ideal choice for mediterranean and creative cuisine in the city.

Following your dinner, dive into the local bar culture at La Botticella Of Poggi Giovanni. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Almalu Trastevere, the perfect place for those looking to experience the best of the nightlife. Similarly, Bar Viminale Di Pepi Maurilio provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Say good night to Rome and look forward to another great day of your road trip in Italy!

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Day 8

Day 8

  • Rome
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Drive 3 km, 42 min

  • Trevi Fountain
  • Pantheon
  • Piazza Navona
  • Trastevere
  • Via del Corso
  • More

On day 8 of your road trip, you will have an entire day to explore Rome. You’ll stay in Rome for 1 night and discover all the best things to see and do in the area.

One of the most iconic places you can visit today in Rome is Trastevere. Allow yourself some time to explore this neighborhood and discover its unique quirks. You'll also find many of the best sightseeing spots nearby. You can also explore Via del Corso, a street that offers a glimpse into local life and culture.

Rome is brimming with adventures. Today’s wonderful stops include a monument and a public square. Begin your sightseeing adventure at the wondrous Trevi Fountain and allow yourself time to explore. Just a short distance away you'll find your next stop, Pantheon, a heritage-rich monument that draws visitors from far and near.

Continue your journey to Piazza Navona, one of the city’s most globally renowned spots that you shouldn’t miss.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Don’t miss out on dining at RomAntica, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Coso Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Cap off your dinner by heading to Sant' Eustachio Caffè, ideal for a leisurely evening with a drink in hand. Yellowsquare Rome is another bar that offers an enjoyable setting. Similarly, Caffè Portofino is also a popular place to go on a night out, perfect for relaxing and socializing.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 9

Day 9

  • Rome
  • Naples
  • More

Drive 238 km, 3 hours 18 min

  • Roman Forum
  • Colosseum
  • Piazza di Spagna
  • More

Experience an unparalleled adventure on day 9 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Rome. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Naples. You will spend 1 night here for some well-deserved relaxation.

Today’s itinerary in Rome covers several incredible sights, including an archeological site and a public square. Start your adventure at Roman Forum. This wondrous archeological site is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the respected wonders of Colosseum, a must-see archeological site in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Piazza Di Spagna. This timeless public square offers an enriching experience. These sights offer a fulfilling end to a perfect day.

When you’re done exploring for the day, you’ll drive to your hotel in Naples. Check in and spend some time relaxing before you head out to tour the city.

As you explore more of Naples, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Dine in style at Opera Restaurant, a top recommendation for dinner tonight. Or, for a change of pace, Trattoria San Ferdinando boasts a menu that's sure to impress. Also, be sure to check out Anonymous Trattoria Gourmet. Known as a local hotspot, it’s a great choice for tonight in Naples.

Continue the enjoyment post-dinner at Gran Caffè Cimmino, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Flanagan's Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Bar Napoli. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Savor another day of unforgettable experiences in Italy!

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Day 10

Day 10

  • Naples - Departure day
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  • Ovo Castle
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Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Naples before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Ovo Castle, a history-steeped castle before you head out.

As your final day in Italy unfolds, enjoy a last-minute shopping spree in Naples's best shopping area, Vomero. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Italy. Browse through boutiques to find unique and stylish fashion pieces to take home. When you need a break, visit a cafe and relax with a cup of coffee or tea.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Naples.

You’ll then say farewell to Naples. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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