10-Day Italy Self-Drive Road Trip With Itinerary from Venice to Florence, Lucca, San Gimignano, and Rome
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Explore the best of Italy on a 10-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Venice, Murano, Florence, Pisa, Lucca, Riomaggiore, Manarola, Corniglia, Levanto, Siena, San Gimignano, Rome, and Santa Maria degli Angeli. This road trip itinerary in Italy seamlessly combines exploration with relaxation.
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Venice, 1 night in Florence, 2 nights in Lucca, 1 night in San Gimignano, and 2 nights in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Venice, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of Piazza San Marco.
As you hit the open road and drive through Venice, Murano, Florence, Pisa, Lucca, Riomaggiore, Manarola, Corniglia, Levanto, Siena, San Gimignano, Rome, and Santa Maria degli Angeli, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
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Day 1
- Venice - Arrival day
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- Rialto Bridge
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Say hello to Venice! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Venice for 2 nights before you continue your adventure!
Venice is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Rialto Bridge, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Find your way to your hotel in Venice. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Venice, it's often a good idea to reserve a table in advance.
Make sure to reserve a table at Bauer Hotel, an iconic dining spot in Venice. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of L'Osteria Le Guglie, a popular restaurant in Venice. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Corner Pub, a hidden gem nestled in Venice. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Al Parlamento, a well-loved spot among locals and tourists. Or, head to The Caffe Rosso. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Adagio, another top-rated place in the area.
Raise a toast to the start of your 10-day road trip in Italy!
Day 2
- Venice
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Drive 14 km, 34 min
- Piazza San Marco
- St Mark's Campanile
- St Mark's Basilica
- Doge's Palace
- Bridge of Sighs
- Murano
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Greet day 2 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Venice for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Venice and Murano.
Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Venice allows for both. Start by heading to Piazza San Marco. This iconic public square provides an insightful glimpse into the city's identity. Next, discover St Mark's Campanile, a romantic monument, promising a delightful encounter.
Continue your sightseeing with a visit to St Mark's Basilica, an interesting church. When you’re done, don’t forget to make a stop at the interesting Doge's Palace. Not far away from the palace, you will find the history-steeped Murano, perfect for a quick visit. Round off your day at Bridge Of Sighs, another gem in Venice with UNESCO world heritage-listed features to discover.
When you’re done exploring for the day, you’ll return to Venice and your accommodation.
After a day of adventure, treat yourself to an exquisite dinner at one of Venice's best restaurants.
Enjoy a delicious meal at Generator Venice, a highly-rated dining destination in Venice. If you're eager to try something different, consider Nevodi, another top spot with a tantalizing menu. You might also want to secure a reservation at Ristorante La Piazza. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Venice this evening.
After enjoying a fulfilling meal, continue your evening at Il Mercante, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, The Irish Pub Venezia offers a welcoming atmosphere for easing into the nightlife. Similarly, Ai Stagneri provides an excellent environment for a relaxed and enjoyable evening.
Relax and recharge in preparation for another adventurous day in Italy!
Day 3
- Venice
- Florence
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Drive 263 km, 3 hours 20 min
- Ponte Vecchio
- Uffizi Gallery
- Basilica of Santa Croce in Florence
- Hercules and Cacus
- piazza della Signoria
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On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Florence. When you’re not sightseeing, take time to relax at your selected hotel in Florence, where you’ll be staying for 1 night.
Immerse yourself in Venice’s rich culture with today's sightseeing itinerary. Start your journey at Ponte Vecchio. This history-steeped historical landmark is sure to ignite your curiosity. Next, dive into the romantic features of Uffizi Gallery, a must-visit art gallery in the city.
In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Basilica Of Santa Croce In Florence, a popular church. We also recommend visiting Piazza Della Signoria. This public square is a must for anyone looking to experience the city to the fullest.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.
Treat yourself to a wonderful meal at Ristorante Oliviero 1962, a top-rated dining spot in Florence. If you're in the mood for something new, try Di Poneta Novoli, another premier location with a delectable menu. You might also want to book a table at Caffe San Firenze. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.
Continue the enjoyment post-dinner at Manifattura, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Se·sto On Arno Rooftop Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Il Vinile. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.
Get a good night's sleep and look forward to another great day on the road in Italy!
Day 4
- Florence
- Lucca
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Drive 109 km, 2 hours 13 min
- Cathedral of Santa Maria del Fiore
- Galleria dell'Accademia
- Piazza del Duomo, Pisa
- Leaning Tower of Pisa
- Walls of Lucca
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Embark on another extraordinary experience on day 4 of your road trip in Italy. Today, you will make 3 stops and experience some of the highlights of Florence, Pisa, and Lucca. At the end of the day, you will enjoy the comforts of a top-rated hotel in Lucca, which will be your home away from home for 2 nights.
Bring your curiosity for today’s adventure around Florence. Some of the city’s most loved attractions await! Cathedral Of Santa Maria Del Fiore is the perfect place to start. This church is one of the most spectacular places to visit in Florence. Next, head to Galleria Dell'accademia, a popular art gallery, known for its heritage-rich features.
In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Piazza Del Duomo, Pisa. This historic public square is a highly recommended experience. Nearby, you'll also find Leaning Tower Of Pisa and Mura Di Lucca. Visit these for an interesting touch to your journey.
At the end of the day, you will drive to Lucca, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Lucca. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Savor the flavors at Gli Orti di Via Elisa, a top pick for dinner tonight. Alternatively, Bar Caffè Ristretto beckons with its unique menu offerings. Also, consider Ristorante Schiaffino. With its consistent customer satisfaction, it’s an excellent option for dining in Lucca tonight.
Extend your evening after a delightful meal by visiting Lebowski - Cocktail Bar, which offers the perfect atmosphere for a night out. Moreover, Blend is another popular option for a drink or two. Likewise, Franklin'33 also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.
Head back to your accommodation in Lucca and get some rest in preparation for another magical day of your road trip in Italy!
Day 5
- Lucca
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Drive 226 km, 4 hours 24 min
- Riomaggiore
- Manarola Overlook Viewpoint
- Cinque Terre National Park
- Saint Andrew's Church
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On day 5 of your road trip, you’ll start and end your day in Lucca, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Riomaggiore, Manarola, Corniglia, and Levanto. You still have 1 night left in Lucca.
Start your adventure at Riomaggiore. This locally appreciated point of interest is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the romantic wonders of Manarola Overlook Viewpoint, a must-see observation deck in the village.
Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Cinque Terre National Park. This captivating national park offers an enriching experience. For a change of pace, head to Saint Andrew's Church, where you can take in standout features. These sights offer a fulfilling end to a perfect day.
When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Lucca.
As dinnertime approaches, it's time to head out for a bite to eat in Lucca. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Enjoy a lovely dining experience at Osteria Nova, a popular restaurant in Lucca. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Lucca at La Bottega di Anna e Leo, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Ristorante Per 21. It’s yet another ideal choice to enhance your time in Lucca tonight.
Continue the enjoyment post-dinner at La Tana Del Boia, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Vinarkia Della Pavona - Cocktail Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Magellano. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.
As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.
Day 6
- Lucca
- San Gimignano
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Drive 185 km, 2 hours 46 min
- Siena Cathedral
- Pinacoteca Nazionale
- piazza del Campo
- Tower of Mangia
- Parco della Rocca
- Piazza del Duomo, San Gimignano
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Dive into day 6 of your remarkable road trip in Italy. Today you will explore Siena and San Gimignano, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in San Gimignano. You’ll stay here for 1 night.
Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Lucca allows for both. Start by heading to Siena Cathedral. This interesting church provides an insightful glimpse into the city's identity. Next, discover Pinacoteca Nazionale, a heritage-rich art gallery, promising a delightful encounter.
Continue your sightseeing with a visit to Piazza Del Campo, a famous public square. When you’re done, don’t forget to make a stop at the often recommended Tower Of Mangia. Not far away from the monument, you will find the romantic Piazza Del Duomo, perfect for a quick visit. Round off your day at Parco Della Rocca, another gem in Lucca with visually striking features to discover.
When you’re done exploring for the day, you’ll drive to your hotel in San Gimignano. Check in and spend some time relaxing before you head out to tour the village.
As dinnertime approaches, it's time to head out for a bite to eat in San Gimignano. If you are looking to dine at a popular restaurant in the village, it's often a good idea to reserve a table in advance.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 7
- San Gimignano
- Rome
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Drive 281 km, 4 hours 9 min
- Castel Sant'Angelo
- Piazza Navona
- Pantheon
- Trevi Fountain
- Piazza di Spagna
- Basilica di Santa Maria Maggiore
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On day 7 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Rome. In the evening, you’ll end up in Rome, where you will stay for 2 nights.
Get ready for a day filled with fun adventures, romantic experiences, and breathtaking views in the charming city of San Gimignano. Your adventure starts at Castel Sant'angelo, an astonishing local hot spot. Another notable attraction to explore is Piazza Navona. This iconic public square is known for its history-steeped appeal.
After soaking in the highlights of these sights, take some time to wander San Gimignano's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Pantheon. This heritage-rich monument offers a fascinating experience that many visitors find memorable. Trevi Fountain is also worth visiting, along with Piazza Di Spagna. These standout landmarks offer unique experiences that add to the day’s enjoyment. End your day at Basilica Di Santa Maria Maggiore. This captivating church provides a fitting finale to your sightseeing.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.
Treat yourself to a delicious dinner at La Bottega Roma, an excellent option for tonight's dining. Looking for something different? Pasta In Corso offers a tantalizing alternative with its diverse menu. And don’t miss Trattoria Vecchia Roma. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Rome.
After savoring a delicious meal, step into the vibrant nightlife at La Botticella Of Poggi Giovanni, where the evening is just getting started. In the same way, Almalu Trastevere offers a unique charm perfect for experiencing the local bar scene in Rome. Bar Viminale Di Pepi Maurilio is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.
Savor another day of unforgettable experiences in Italy!
Day 8
- Rome
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Drive 16 km, 1 hour 15 min
- St Peter's Basilica
- Colosseum
- Roman Forum
- Capitoline Hill
- Altare della Patria
- Archbasilica of St. John Lateran
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Wake up to day 8 of your extraordinary road trip in Italy. With 1 night left in Rome, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!
Start by visiting St. Peter's Basilica, a prime spot to begin your journey. Next on your list is Colosseum, another must-visit landmark and iconic archeological site renowned for its UNESCO world heritage-designated features.
While exploring and sightseeing, take time to savor the culture of Rome by sampling some local delicacies. When you’re ready for more sightseeing, head to Roman Forum. This UNESCO world heritage-listed archeological site is an essential place to visit for anyone looking for the full Rome experience. We also recommend visiting Capitoline Hill, a notable public square. Nearby, you'll also find Altare Della Patria, ready to add charm to your journey. End your self-guided sightseeing tour with a stop at Archbasilica Of St. John Lateran and wrap up your day with its monumental appeal.
When you’re done exploring for the day, you’ll return to Rome and your accommodation.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Enjoy a delicious meal at RomAntica, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Coso Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.
If you’re not ready to end the night just yet, Sant' Eustachio Caffè offers a perfect venue to relax and savor a drink. Similarly, Yellowsquare Rome is well-suited for those looking to unwind in a social setting. Caffè Portofino is another excellent spot to enjoy a nightcap after a delightful meal.
Raise your glass and celebrate another amazing day of your road trip in Italy!
Day 9
- Rome
- Venice
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Drive 608 km, 7 hours 21 min
- Piazza del Comune
- Portico of Monte Frumentario
- Basilica of San Francesco d'Assisi
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Experience an unparalleled adventure on day 9 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Santa Maria degli Angeli. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Venice. You will spend 1 night here for some well-deserved relaxation.
Get ready for an exciting day in Rome. Today’s sightseeing agenda includes a public square, a historical landmark, and a church. Begin your adventure at Piazza Del Comune. This is an up-and-coming public square you should not miss. Another must-see is Portico Of Monte Frumentario, an up-and-coming historical landmark in Rome.
When you’re ready for the next sight, head to Basilica Of San Francesco D'assisi.
At the end of the day, you will drive to Venice, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Make sure to reserve a table at Osteria Alla Staffa, an iconic dining spot in Venice. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bistrot de Venise, a popular restaurant in Venice. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Corte Sconta, a hidden gem nestled in Venice. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
Continue your lively evening at Dolce Vita Venezia, a perfect place for winding down or revving up the night, depending on which mood you’re in. Tarnowska's American Bar is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Bar All'angolo ensures a night out tailored to your taste.
Say good night to Venice and look forward to another great day of your road trip in Italy!
Day 10
- Venice - Departure day
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- Palazzo Contarini del Bovolo
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Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Venice before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, begin at Palazzo Contarini Del Bovolo. This notable palace is a popular place to see in the city.
Make the most of your final day in Italy by visiting Venice’s iconic markets and shopping establishments in the buzzing Calle Larga XXII Marzo. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Italy. Elevate your style with pieces from high-end retail stores.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Venice.
If you're eager to try something different, consider Trattoria Al Gazzettino, another top spot with a tantalizing menu.
You’ll then say farewell to Venice. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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