10-Day Italy Self-Drive Road Trip With Itinerary from Venice traveling south to Florence, Rome, and Siena

Day 2 of your road trip across Italy promises a magnificent time exploring Venice. You have 1 night left in Venice. Take the opportunity to experience more of the best attractions and activities in the city.

Venice is brimming with adventures. Today’s wonderful stops include an art gallery, an opera house, a public square, a church, a palace, a monument and much more! Begin your sightseeing adventure at the captivating Peggy Guggenheim Collection and allow yourself time to explore. Just a short distance away you'll find your next stop, Teatro La Fenice, a historic opera house that draws visitors from far and near.

Continue your journey to Piazza San Marco, one of the city’s most iconic spots that you shouldn’t miss. Another great site to visit is the captivating St Mark's Basilica. When you're finished at the church, Doge's Palace awaits your visit. This palace is an UNESCO world heritage-listed highlight on today's itinerary. Last up is a monument - the notable Bridge Of Sighs.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Indulge in a memorable dining experience at one of Venice's most popular restaurants, and connect with friendly locals for an authentic adventure.

Don’t miss out on dining at Generator Venice, a top-rated dining destination in Venice. If you're in the mood to try something new, consider Nevodi, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante La Piazza. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Venice this evening.

Keep the evening going at Il Mercante, a great choice for enjoying the after-dinner hours with a drink. You could also go to The Irish Pub Venezia, which offers a similarly pleasant setting and great drinks. Another option is Ai Stagneri, which provides an inviting environment for unwinding after a busy day out.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Florence. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Florence. You will spend 2 nights here for some well-deserved relaxation.

Today, you'll explore some of the most beautiful places in Venice, including a church, an art gallery, a historical landmark, a public square, a palace and much more! Start your day with a visit to Basilica Of Santa Croce In Florence. This popular church is a must-visit in the city. When you’re ready for your next discovery, continue to Uffizi Gallery, which may be one of the most picture-perfect places you will experience today.

One of the best things about exploring Venice on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Ponte Vecchio, a timeless historical landmark in the city. If you’re up for more discoveries, don’t forget to reserve some time for Loggia Dei Lanzi and Palazzo Vecchio. End your day with a visit to Piazza Della Signoria, a famous public square that’s sure to leave a lasting impression.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Enjoy a delicious meal at Ristorante Oliviero 1962, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Di Poneta Novoli, another top spot with a mouthwatering menu. You might also want to secure a reservation at Caffe San Firenze. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

Explore the vibrant nightlife at Manifattura after your meal, a hub for lively evenings and memorable moments. Or, head to Se·sto On Arno Rooftop Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Il Vinile is perfect for those looking to extend their night with a touch of local flavor.

Head back to your accommodation in Florence and get some rest in preparation for another magical day of your road trip in Italy!

Greet day 4 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Florence for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Florence and Pisa.

Florence is brimming with adventures. Today’s wonderful stops include an art gallery, a museum, a church, a monument, a public square and much more! Begin your sightseeing adventure at the well-known Galleria Dell'accademia and allow yourself time to explore. Just a short distance away you'll find your next stop, Museo Dell'opera Del Duomo, a culturally significant museum that draws visitors from far and near.

Continue your journey to Florence Baptistery, one of the city’s most curiosity-inducing spots that you shouldn’t miss. Another great site to visit is the globally renowned Leaning Tower Of Pisa. When you're finished at the monument, Piazza Del Duomo, Pisa awaits your visit. This public square is a grand highlight on today's itinerary. Last up is a church - the frequently visited Battistero Di San Giovanni.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at Ditta Artigianale, an excellent option for tonight's dining. Looking for something different? Trattoria Da Burde offers a tantalizing alternative with its diverse menu. And don’t miss Casa Toscana. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Florence.

Explore the vibrant nightlife at Bar 50 Rosso after your meal, a hub for lively evenings and memorable moments. Or, head to Bitter Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Archea Brewery is perfect for those looking to extend their night with a touch of local flavor.

Celebrate another amazing day of your road trip adventure in Italy!

On day 5 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Orvieto and Rome. In the evening, you’ll end up in Rome, where you will stay for 3 nights.

Start by visiting Orvieto Cathedral, a prime spot to begin your journey. This romantic church is sure to impress. Next on your list is Spanish Steps, another must-visit landmark and spectacular public square renowned for its culturally significant features.

While exploring and sightseeing, take time to savor the culture of Florence by sampling some local delicacies. When you’re ready for more sightseeing, head to Piazza Di Spagna. This enchanting public square is an essential place to visit for anyone looking for the full Florence experience. We also recommend visiting Trevi Fountain, a globally renowned monument. Nearby, you'll also find Pantheon, ready to add charm to your journey. End your self-guided sightseeing tour with a stop at Circus Maximus and wrap up your day with its breathtaking appeal.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Dine in style at La Bottega Roma, a top recommendation for dinner tonight. Or, for a change of pace, Pasta In Corso boasts a menu that's sure to impress. Also, be sure to check out Trattoria Vecchia Roma. Known as a local hotspot, it’s a great choice for tonight in Rome.

Continue your lively evening at La Botticella Of Poggi Giovanni, a perfect place for winding down or revving up the night, depending on which mood you’re in. Almalu Trastevere is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Bar Viminale Di Pepi Maurilio ensures a night out tailored to your taste.

Relax and recharge in preparation for another adventurous day in Italy!

Day 6 of your road trip will take you to the best attractions Rome has to offer. Cherish the 2 nights you have left in Rome by discovering the best things there are to see and do in the city.

Today’s itinerary in Rome covers several incredible sights, including an archeological site, a monument, a public square, a castle and much more! Start your adventure at Colosseum. This iconic archeological site is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the historic wonders of Roman Forum, a must-see archeological site in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Altare Della Patria. This popular monument offers an enriching experience. For a change of pace, head to Campo De' Fiori, where you can take in romantic features. Conclude your self-guided sightseeing tour with a visit to Piazza Navona and Castel Sant'angelo. These sights offer a fulfilling end to a perfect day.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a wonderful meal at RomAntica, a top-rated dining spot in Rome. If you're in the mood for something new, try Coso Ristorante, another premier location with a delectable menu. You might also want to book a table at DEROMA - Farine Romane. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.

Continue your evening by exploring the vibrant nightlife scene at Sant' Eustachio Caffè, a prime destination for a thrilling night out. Also, don’t forget to check out Yellowsquare Rome, a bar that offers unique local touches. Likewise, Caffè Portofino provides an excellent alternative for a fun evening.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 7 of your road trip in Italy, you’ll start and end your day in Rome, but spend the day exploring what’s beyond the city. Since you will return to Rome for 1 night more, there’s no need to rush. Experience Vatican City and Rome to the fullest today with this curated day itinerary!

A top thing to do today is to explore Trastevere, a must-see neighborhood in Vatican City. It's the perfect starting point for touring the top attractions in the area.

Rome is home to plenty of attractions that offer family-friendly attractions, romantic experiences, and scenic views! Start at St. Peter's Basilica, a wondrous major basilica that is worthwhile a visit in the city. Continue your exploration at Saint Peter's Square. This square is one of the city’s most interesting spots.

Enjoy the freedom of exploring Rome at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Vatican Museums. After exploring the art museum, head to the top-rated Piazza Del Popolo.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Enjoy a lovely meal at Hotel de Russie, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, La Taverna Italiana is another top choice with a popular menu. You could also check for a table at The Parrot Bar. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Rome tonight.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at The Apartment Bar Roma, a well-loved spot among locals and tourists. Or, head to Hotel Hassler Roma. This bar boasts a welcoming environment that is perfect for winding down.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

Dive into day 8 of your remarkable road trip in Italy. Today you will explore Siena, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Siena. You’ll stay here for 1 night.

Enjoy the perfect balance of relaxation and exploration in Rome today. One of the most locally appreciated attractions included on the itinerary is Porta Camollia, Siena. This breathtaking monument will help you start your sightseeing on top. Then, take a leisurely stroll to Basilica Of San Domenico and learn what makes this stunning church unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the captivating Siena Cathedral. After exploring the church, head to Pubblico Palace. This intriguing palace is a highlight in Rome. As your day continues, stop by Piazza Del Campo, known for its UNESCO world heritage-designated features. Lastly, don’t forget to check out the underrated Tower Of Mangia. Enjoy exploring this incredible monument at your own pace.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Siena. Siena offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Siena, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Make sure to reserve a table at Enoteca I Terzi, an iconic dining spot in Siena. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante Tar-Tufo, a popular restaurant in Siena. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Antica Trattoria Papei, a hidden gem nestled in Siena. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Extend your evening after a delightful meal by visiting Meet Life Cafè, which offers the perfect atmosphere for a night out. Moreover, Maudit Pub is another popular option for a drink or two. Likewise, Bar Impero Siena also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Say good night to Siena and look forward to another great day of your road trip in Italy!

On day 9 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Bologna. When you’re not sightseeing, take time to relax at your selected hotel in Venice, where you’ll be staying for 1 night.

Brace yourself for today’s incredible lineup of attractions in Siena, featuring family-friendly attractions, romantic experiences, and photo-friendly spots. Start at Palazzo Pallavicini, a frequently visited palace in the city. Then, head to Chiesa Del Santissimo Salvatore and soak in the ambiance of this photogenic church.

There are many interesting places to see in Siena, and when you are ready for more, go to Piazza Maggiore. This is one of the city’s most extraordinary visually striking spots of interest. After exploring the public square, visit the notable Two Towers. Not far away, you'll also find Bologna Cathedral. This church is a breathtaking highlight in Siena. Before wrapping up your self-guided sightseeing tour, head to Fountain Of Neptune, Bologna, a worthwhile monument in the city.

At the end of the day, you will drive to Venice, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Venice's most popular restaurants, and connect with friendly locals for an authentic adventure.

Savor the flavors at Osteria Alla Staffa, a top pick for dinner tonight. Alternatively, Bistrot de Venise beckons with its unique menu offerings. Also, consider Corte Sconta. With its consistent customer satisfaction, it’s an excellent option for dining in Venice tonight.

After your meal, keep the night alive at a bar like Dolce Vita Venezia, known for its lively atmosphere. Tarnowska's American Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Bar All'angolo offers an excellent atmosphere for those looking to amp up the evening.

Raise your glass to another unforgettable day in Italy!