12-Day Italy Self-Drive Road Trip With Itinerary from Pescara traveling west to Santa Maria degli Angeli, Florence, Siena, and Rome

On day 2 of your road trip, you will have an entire day to explore Pescara. You’ll stay in Pescara for 1 night and discover all the best things to see and do in the area.

Today’s route brings family-friendly attractions, photo-friendly spots, and sacred landmarks. The first attraction of today is Church Stella Maris. This beloved church is a photogenic place to see in Pescara. Continue your discovery at Nature Reserve Pineta Dannunziana, a romantic nature reserve with stories to tell.

As you stroll around Pescara, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Museo Delle Genti D'abruzzo. This underrated museum offers a respected encounter with Pescara. Next, make your way to Ponte Del Mare to add another highlight to your day. After that, visit Parco Giochi Paperopoli, an intriguing sightseeing destination that’s sure to impress. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Pescara.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Pescara's best restaurants.

Enjoy a lovely meal at Ciacco, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Bar Sara is another top choice with a popular menu. You could also check for a table at Ristorante Franco. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Pescara tonight.

After savoring a delicious meal, step into the vibrant nightlife at Bar Napoli, where the evening is just getting started. In the same way, Bar Supermarket offers a unique charm perfect for experiencing the local bar scene in Pescara. Post Bar is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Take some time to reflect on your day and savor another beautiful night in Italy.

Embark on another extraordinary experience on day 3 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Santa Maria degli Angeli. At the end of the day, you will enjoy the comforts of a top-rated hotel in Santa Maria degli Angeli, which will be your home away from home for 1 night.

Get ready for an exciting day in Pescara. Today’s sightseeing agenda includes a monastery, a church, a castle, a public square and much more! Begin your adventure at Eremo Delle Carceri. This is a worthwhile monastery you should not miss. Another must-see is Basilica Of Santa Maria Degli Angeli, a notable church in Pescara.

When you’re ready for the next sight, head to Basilica Of San Francesco D'assisi. From there, take a leisurely stroll to Rocca Maggiore, another of the town’s intriguing attractions. We recommend continuing your self-guided tour at Piazza Del Comune, a majestic place of interest in the town.

When you’re done exploring for the day, you’ll drive to your hotel in Santa Maria degli Angeli. Check in and spend some time relaxing before you head out to tour the town.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Santa Maria degli Angeli. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Cap off your dinner by heading to Bibenda Assisi Wine Tasting & Gourmet Food, Olive Oil And Chocolate Tastings, ideal for a leisurely evening with a drink in hand.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 4 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Florence. In the evening, you’ll end up in Florence, where you will stay for 2 nights.

Brace yourself for today’s incredible lineup of attractions in Santa Maria degli Angeli, featuring fun adventures, romantic experiences, and scenic views. Start at Piazzale Michelangelo, a famous observation deck in the city. Then, head to Basilica Of Santa Croce In Florence and soak in the ambiance of this standout church.

There are many interesting places to see in Santa Maria degli Angeli, and when you are ready for more, go to Ponte Vecchio. This is one of the city’s most timeless visually striking spots of interest. After exploring the historical landmark, visit the impressive Uffizi Gallery. Not far away, you'll also find Palazzo Vecchio. This palace is a grand highlight in Santa Maria degli Angeli. Before wrapping up your self-guided sightseeing tour, head to Piazza Della Signoria, an extraordinary public square in the city.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at Ristorante Oliviero 1962, a highly-rated dining destination in Florence. If you're eager to try something different, consider Di Poneta Novoli, another top spot with a tantalizing menu. You might also want to secure a reservation at Caffe San Firenze. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Florence this evening.

Extend your evening after a delightful meal by visiting Manifattura, which offers the perfect atmosphere for a night out. Moreover, Se·sto On Arno Rooftop Bar is another popular option for a drink or two. Likewise, Il Vinile also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

Day 5 offers a multitude of experiences. You will stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.

One of the most iconic places you can visit today in Florence is Oltrarno. Allow yourself some time to explore this neighborhood and discover its unique quirks. You'll also find many of the best sightseeing spots nearby.

Prepare for a day full of family-friendly attractions, romantic experiences, and scenic views. When you’re ready, kick off your sightseeing adventure at The Boboli Gardens. This captivating botanical garden is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Basilica Of San Lorenzo, one of the city’s best highlights.

Next, check out Central Market, one of the most popular places to see in Florence. This food market is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Galleria Dell'accademia. Wander around and soak in the eye-catching atmosphere this art gallery offers. Then, head to Cathedral Of Santa Maria Del Fiore, a top-rated church that adds another dimension to your day.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at Ditta Artigianale, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Trattoria Da Burde, another top spot with a mouthwatering menu. You might also want to secure a reservation at Casa Toscana. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

Explore the vibrant nightlife at Bar 50 Rosso after your meal, a hub for lively evenings and memorable moments. Or, head to Bitter Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Archea Brewery is perfect for those looking to extend their night with a touch of local flavor.

Raise your glass to another unforgettable day in Italy!

Dive into day 6 of your remarkable road trip in Italy. Today you will explore Siena, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Siena. You’ll stay here for 2 nights.

Today’s route brings fun adventures, scenic views, and photo-friendly spots. The first attraction of today is Fortezza Medicea (siena). This often recommended monument is a historic place to see in Florence. Continue your discovery at Basilica Of San Domenico, a historic church with stories to tell.

As you stroll around Florence, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Siena Cathedral. This interesting church offers a culturally significant encounter with Florence. Next, make your way to Pubblico Palace to add another highlight to your day. After that, visit Piazza Del Campo, a spectacular public square that’s sure to impress. If you’re up for more, end your self-guided sightseeing tour at Tower Of Mangia, a beloved monument in the city. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Florence.

At the end of the day, you will drive to Siena, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Siena. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Enoteca I Terzi, a top-rated dining destination in Siena. If you're in the mood to try something new, consider Ristorante Tar-Tufo, another top spot with a mouthwatering menu. You might also want to secure a reservation at Antica Trattoria Papei. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Siena this evening.

Continue your evening by exploring the vibrant nightlife scene at Meet Life Cafè, a prime destination for a thrilling night out. Also, don’t forget to check out Maudit Pub, a bar that offers unique local touches. Likewise, Bar Impero Siena provides an excellent alternative for a fun evening.

Raise your glass to another unforgettable day in Italy!

On day 7 of your road trip, you’ll start and end your day in Siena, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in San Gimignano. You still have 1 night left in Siena.

Get ready for a day filled with family-friendly attractions, breathtaking views, and photo-friendly spots in the charming village of Siena. Your adventure starts at Porta San Giovanni, a locally appreciated local hot spot. Another notable attraction to explore is Sangimignano1300. This beloved museum is known for its breathtaking appeal.

After soaking in the highlights of these sights, take some time to wander Siena's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Palazzo Comunale, Pinacoteca, Torre Grossa. This culturally significant museum offers a fascinating experience that many visitors find memorable. Piazza Del Duomo is also worth visiting, along with Parco Della Rocca. These standout landmarks offer unique experiences that add to the day’s enjoyment. End your day at Chiesa Di Sant'agostino. This locally appreciated church provides a fitting finale to your sightseeing.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Siena.

Indulge in a memorable dining experience at one of Siena's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a delicious dinner at Osteria Quattro Venti, an excellent option for tonight's dining. Looking for something different? Fischi per Fiaschi offers a tantalizing alternative with its diverse menu. And don’t miss Osteria da Divo. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Siena.

Keep the evening going at Charlie Mixology Bar Di Aldinucci Riccardo, a great choice for enjoying the after-dinner hours with a drink. You could also go to Bar Pinacoteca, which offers a similarly pleasant setting and great drinks. Another option is San Paolo Pub, which provides an inviting environment for unwinding after a busy day out.

Relax and recharge in preparation for another adventurous day in Italy!

On day 9 of your road trip, you’ll start and end your day in Rome, where you'll stay for 2 nights more.

Brace yourself for today’s incredible lineup of attractions in Rome, featuring family-friendly attractions, romantic experiences, and breathtaking views. Start at Vatican Museums, a world-famous art museum in the city.

After exploring the major basilica, visit the globally renowned Piazza Navona. Not far away, you'll also find Pantheon. This monument is an inviting highlight in Rome. Before wrapping up your self-guided sightseeing tour, head to Trevi Fountain, a world-famous monument in the city.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a delicious meal at RomAntica, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Coso Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Unwind after your meal by stepping into Sant' Eustachio Caffè. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Yellowsquare Rome offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Caffè Portofino, another top-rated bar in the area.

Take some time to reflect on your day and savor another beautiful night in Italy.

Day 10 of your road trip across Italy promises a magnificent time exploring Rome. You have 1 night left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

A visit to Via del Corso in Rome is a must on the agenda today. This street is full of hidden gems and character, perfect for a leisurely stroll. Plus, you’ll be close to some of the city’s most famous sights. Don’t forget to check out Via dei Condotti as well, a street that adds another layer to your exploration.

Today’s agenda in Rome includes a castle, a public square, and a park. Castel Sant'angelo is must-visit castle and a great starting point for the day. Next, continue your journey to Piazza Di Spagna, an iconic public square, located just a leisurely stroll away. Next, head to Spanish Steps, a romantic public square, also available for your discovery today.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Make sure to reserve a table at Hotel de Russie, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of La Taverna Italiana, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of The Parrot Bar, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

To truly maximize your evening out, consider visiting The Apartment Bar Roma after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Hotel Hassler Roma, another bar with an inviting ambiance.

Savor another day of unforgettable experiences in Italy!

Experience an unparalleled adventure on day 11 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Orvieto. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Pescara. You will spend 1 night here for some well-deserved relaxation.

Today’s itinerary in Rome covers several incredible sights, including a monument, a church, a museum, a cave system, a cave and much more! Start your adventure at Well Of St. Patrick. This notable monument is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the history-steeped wonders of Orvieto Cathedral, a must-see church in the village.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Museo Dell'opera Del Duomo. This curiosity-inducing museum offers an enriching experience. For a change of pace, head to Orvieto Underground, where you can take in photogenic features. Conclude your self-guided sightseeing tour with a visit to Torre Del Moro Orvieto and Pozzo Della Cava. These sights offer a fulfilling end to a perfect day.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Pescara. Pescara offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Pescara's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a delightful dinner at MuuLab. Cucina e Distillati, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try La Taverna Antica? It's another excellent option with a diverse menu. Consider reserving a table at Ristorante La griglia dell'Orso as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Pescara.

Let the evening flow smoothly from dinner to drinks at Enoteca Visaggio Cocktails And Wine, a top-rated bar in the area. For other recommendations, Giro' Loungebar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Caffè Ideale offers a memorable night with diverse drink options and excellent service.

Say good night to Pescara and look forward to another great day of your road trip in Italy!