14-Day Italy Self-Drive Road Trip With Itinerary from Genoa to La Spezia, Florence, Siena, Rome, and Naples

On day 2 of your road trip, you will have an entire day to explore Genoa. You’ll stay in Genoa for 1 night and discover all the best things to see and do in the area.

Prepare for a day full of fun adventures, romantic experiences, and breathtaking views. When you’re ready, kick off your sightseeing adventure at Porto Antico. This captivating public square is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Aquarium Of Genoa, one of the city’s best highlights.

Next, check out Chiesa Di San Pietro In Banchi, one of the most locally appreciated places to see in Genoa. This church is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Genoa Cathedral. Wander around and soak in the photogenic atmosphere this church offers. Then, head to Palazzo Podestà, a top-rated palace that adds another dimension to your day. Finally, visit the underrated Via Garibaldi, the last of our attraction recommendations for today.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Genoa. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Zeffirino, a top-rated dining destination in Genoa. If you're in the mood to try something new, consider Trattoria Vegia Zena, another top spot with a mouthwatering menu. You might also want to secure a reservation at Trattoria delle Grazie. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Genoa this evening.

Get a good night's sleep and look forward to another great day on the road in Italy!

Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Corniglia and Manarola. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in La Spezia. You will spend 2 nights here for some well-deserved relaxation.

Set out on a day brimming with fun adventures, romantic experiences, and natural wonders. Start at the frequently visited Sentiero Azzurro, a serene hiking area in Genoa. Next, go to Cinque Terre National Park.

After visiting Sentiero Azzurro and Cinque Terre National Park, have a stroll along Genoa's streets and take in the local charm. Continue your sightseeing by heading to Manarola Overlook Viewpoint. This eye-catching observation deck offers a unique experience.

When you’re done exploring for the day, you’ll drive to your hotel in La Spezia. Check in and spend some time relaxing before you head out to tour the city.

Indulge in a memorable dining experience at one of La Spezia's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a delicious meal at The Colombaio Park, a top-rated dining destination in La Spezia.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

At the end of the day, you'll drive back to La Spezia, where you'll stay for 1 night more.

Start your day at Nostra Signora Di Montenero. This history-steeped church is a beloved place to see in La Spezia. Then, wander over to Riomaggiore. Nearby, you’ll also find Castle Of Riomaggiore. This enchanting castle is a favorite among visitors.

When you’re done exploring for the day, you’ll return to La Spezia and your accommodation.

As you explore more of La Spezia, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

With its reputation for pleasing customers, it’s a fantastic choice for tonight in La Spezia.

Celebrate another amazing day of your road trip adventure in Italy!

On day 5 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Florence. In the evening, you’ll end up in Florence, where you will stay for 2 nights.

Today’s agenda in La Spezia includes a museum, a palace, an art gallery, a historical landmark, a public square and much more! Bargello National Museum is must-visit museum and a great starting point for the day. Next, continue your journey to Palazzo Vecchio, a captivating palace, located just a leisurely stroll away. Next, head to Uffizi Gallery, a romantic art gallery, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for La Spezia. When you're ready, let your sightseeing route take you to the world-famous Ponte Vecchio. If you’re looking for more, Piazza Della Signoria is also a top-rated attraction that is worthwhile a visit.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a lovely meal at Ristorante Oliviero 1962, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Di Poneta Novoli is another top choice with a popular menu. You could also check for a table at Caffe San Firenze. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Florence tonight.

Keep the evening going at Manifattura, a great choice for enjoying the after-dinner hours with a drink. You could also go to Se·sto On Arno Rooftop Bar, which offers a similarly pleasant setting and great drinks. Another option is Il Vinile, which provides an inviting environment for unwinding after a busy day out.

Raise your glass to another unforgettable day in Italy!

Day 6 offers a multitude of experiences. You will stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.

Discover a day packed with family-friendly attractions, picturesque spots, and history-rich sites in Florence. Begin your sightseeing with David. This notable statue is one of the top attractions in the city. Proceed to Galleria Dell'accademia, another must-visit attraction.

As you wander through the inviting streets of Florence, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Cathedral Of Santa Maria Del Fiore. This extraordinary church is a traveler-favorite. Not far away, you’ll find Basilica Of Santa Croce In Florence, another key site on your sightseeing itinerary. Piazzale Michelangelo is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Dine in style at Ditta Artigianale, a top recommendation for dinner tonight. Or, for a change of pace, Trattoria Da Burde boasts a menu that's sure to impress. Also, be sure to check out Casa Toscana. Known as a local hotspot, it’s a great choice for tonight in Florence.

After your meal, keep the night alive at a bar like Bar 50 Rosso, known for its lively atmosphere. Bitter Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Archea Brewery offers an excellent atmosphere for those looking to amp up the evening.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Dive into day 7 of your remarkable road trip in Italy. Today you will explore Siena, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Siena. You’ll stay here for 1 night.

Prepare for a day full of fun adventures, scenic views, and photo-friendly spots. When you’re ready, kick off your sightseeing adventure at Basilica Of San Domenico. This beloved church is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Siena Cathedral, one of the city’s best highlights.

Next, check out Pubblico Palace, one of the most intriguing places to see in Florence. This palace is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Piazza Del Campo. Wander around and soak in the romantic atmosphere this public square offers. Then, head to Tower Of Mangia, a top-rated monument that adds another dimension to your day.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Siena. Siena offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Siena's best restaurants.

Treat yourself to a delightful dinner at Enoteca I Terzi, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Ristorante Tar-Tufo? It's another excellent option with a diverse menu. Consider reserving a table at Antica Trattoria Papei as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Siena.

To truly maximize your evening out, consider visiting Meet Life Cafè after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Maudit Pub, another bar with an inviting ambiance. Similarly, Bar Impero Siena also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Relax and recharge in preparation for another adventurous day in Italy!

Embark on another extraordinary experience on day 8 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Rome. At the end of the day, you will enjoy the comforts of a top-rated hotel in Rome, which will be your home away from home for 3 nights.

Siena is brimming with adventures. Today’s wonderful stops include a castle, a public square, and a monument. Begin your sightseeing adventure at the astonishing Castel Sant'angelo and allow yourself time to explore. Just a short distance away you'll find your next stop, Spanish Steps, a romantic public square that draws visitors from far and near.

Continue your journey to Piazza Di Spagna, one of the city’s most timeless spots that you shouldn’t miss. Another great site to visit is the timeless Trevi Fountain. When you're finished at the monument, Pantheon awaits your visit. This monument is a heritage-rich highlight on today's itinerary.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Make sure to reserve a table at La Bottega Roma, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Pasta In Corso, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Trattoria Vecchia Roma, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your meal, keep the night alive at a bar like La Botticella Of Poggi Giovanni, known for its lively atmosphere. Almalu Trastevere is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Bar Viminale Di Pepi Maurilio offers an excellent atmosphere for those looking to amp up the evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

On day 9 of your road trip in Italy, you’ll start and end your day in Rome, but spend the day exploring what’s beyond the city. Since you will return to Rome for 2 nights more, there’s no need to rush. Experience Vatican City and Rome to the fullest today with this curated day itinerary!

A top thing to do today is to explore Trastevere, a must-see neighborhood in Vatican City. It's the perfect starting point for touring the top attractions in the area.

Begin your adventure at Vatican Museums. This is a timeless art museum you should not miss. Another must-see is Sistine Chapel, a top-rated chapel in Rome.

When you’re ready for the next sight, head to St. Peter's Basilica. From there, take a leisurely stroll to Campo De' Fiori, another of the city’s widely recognized attractions. We recommend continuing your self-guided tour at Piazza Navona, an enchanting place of interest in the city.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at RomAntica, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Coso Ristorante, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of DEROMA - Farine Romane, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your meal, keep the night alive at a bar like Sant' Eustachio Caffè, known for its lively atmosphere. Yellowsquare Rome is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Caffè Portofino offers an excellent atmosphere for those looking to amp up the evening.

Raise your glass to another unforgettable day in Italy!

Day 10 of your road trip will take you to the best attractions Rome has to offer. Cherish the 1 night you have left in Rome by discovering the best things there are to see and do in the city.

Today’s well-planned self-sightseeing route offers several family-friendly attractions, scenic views, and picturesque spots. Whether you decide to explore Rome on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Colosseum is the first of them. Spend some time admiring this UNESCO world heritage-listed archeological site before continuing your journey. Arch Of Constantine is your next stop. This underrated monument is one of the best-rated sights in Rome.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Roman Forum. This UNESCO world heritage-designated archeological site is a sight to behold. To round off your sightseeing experience, visit Capitoline Hill and Capitoline Museums. If time allows, end your day with Altare Della Patria, a remarkable monument that offers a memorable conclusion to your exploration.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Make sure to reserve a table at Hotel de Russie, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of La Taverna Italiana, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of The Parrot Bar, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Round off your dining experience by visiting The Apartment Bar Roma, a prime location for a drink. Alternatively, explore the distinctive characteristics of Hotel Hassler Roma, a bar catering to every mood and preference.

Celebrate another amazing day of your road trip adventure in Italy!

On day 11 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Naples. When you’re not sightseeing, take time to relax at your selected hotel in Naples, where you’ll be staying for 2 nights.

Today’s itinerary in Rome covers several incredible sights, including a castle, a museum, and a street. Start your adventure at Castel Sant'elmo. This captivating castle is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the history-steeped wonders of Naples National Archaeological Museum, a must-see museum in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Cappella Sansevero. This well-known museum offers an enriching experience. For a change of pace, head to Spaccanapoli, where you can take in history-steeped features. These sights offer a fulfilling end to a perfect day.

At the end of the day, you will drive to Naples, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Naples, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a wonderful meal at L'Oca Nera Irish Pub, a top-rated dining spot in Naples. If you're in the mood for something new, try Mimì alla Ferrovia, another premier location with a delectable menu. You might also want to book a table at Spuzzulè Winebar. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Naples.

Cap off your dinner by heading to Happening Cocktail Bar, ideal for a leisurely evening with a drink in hand. Shanti Art Musik Bar is another bar that offers an enjoyable setting. Similarly, Gran Caffè Gambrinus is also a popular place to go on a night out, perfect for relaxing and socializing.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Wake up to day 12 of your extraordinary road trip in Italy. With 1 night left in Naples, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Today's adventure in Naples promises more breathtaking discoveries and enriching experiences! Begin at Archaeological Park Of Pompeii. This historic archeological site is a highlight of any visit in the town. Then, enjoy Archaeological Park Of Herculaneum, another picture-perfect attraction that never fails to captivate visitors. Next, head over to Mount Vesuvius, one of the town’s most increasingly popular attractions, known for its history-steeped features.

When you’re done exploring for the day, you’ll return to Naples and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Naples. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at Antica Pizzeria Di Matteo, a highly-rated dining destination in Naples. If you're eager to try something different, consider Mercure Napoli Centro Angioino, another top spot with a tantalizing menu. You might also want to secure a reservation at La Lazzara Trattoria e Pizzeria. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Naples this evening.

Extend your evening after a delightful meal by visiting Archivio Storico - Cocktail Bar & Wonderfood, which offers the perfect atmosphere for a night out. Moreover, Archeobar is another popular option for a drink or two. Likewise, Babette Pub also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Head back to your accommodation in Naples and get some rest in preparation for another magical day of your road trip in Italy!

Experience an unparalleled adventure on day 13 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Pisa. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Genoa. You will spend 1 night here for some well-deserved relaxation.

Naples is home to plenty of attractions that offer family-friendly attractions, breathtaking views, and photo-friendly spots! Start at Leaning Tower Of Pisa, a globally renowned monument that is worthwhile a visit in the city. Nearby, you’ll find Museo Dell'opera Del Duomo, enchanting visitors with its photogenic appeal. Continue your exploration at Porta Nuova. This monument is one of the city’s most worthwhile spots.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Genoa. Genoa offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Genoa. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at Osteria Sant'Ilario, a popular restaurant in Genoa. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Genoa at La Cialtroneria, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Manhattan Bar. It’s yet another ideal choice to enhance your time in Genoa tonight.

Savor another day of unforgettable experiences in Italy!