6-Day Italy Self-Drive Road Trip With Itinerary from Brindisi to Sorrento and Rome

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Ostuni white town skyline at sunset, Brindisi, Apulia southern Italy. Europe.
Ostuni white town skyline at sunset, Brindisi, Apulia southern Italy. Europe.
A sidewalk cafe with covered patio at the seaside promenade and boardwalk in the city of Brindisi, Italy, in the Puglia region.
Alfonsino castle, located at the entrance to the port of the Italian town of Brindisi, is an interesting example of defensive architecture.
Empty streets and closed shops and cafes on a summer morning on the main street, Corso Umberto, through the town center of the coastal city of Brindisi, Italy.
Photo of Brindisi harbour.
Morning as tourists begin to explore the Brindisi Duomo Cathedral and Bell tower in the Piazza Duomo in Brindisi, Italy, part of the southern Puglia region.
military monument seen from the harbor of Brindisi
photo of view of Panoramic view of Brindisi. Puglia. Italy.
photo of view of Brindisi, Italy.
photo of view of Barletta, Brindisi, Italy.
photo of view of Seafront. Brindisi. Puglia. Italy.
photo of view of Panoramic view of Ostuni white town, Brindisi, Puglia (Apulia), Italy,
photo of view of Piazza Duomo with Brindisi Cathedral near Archiological museum, Brindisi, Italy.
Aerial view of Sorrento city, amalfi coast, Italy
Morning view of Amalfi cityscape on coast line of mediterranean sea, Italy
People swimming in crystal clear blue waters on a hidden beach. Bird View of a beautiful golf called Regina Giovanna in Sorrento, Italy
View of the sea and the beaches of Sorrento, Italy.
Panoramic view of Sorrento, the Amalfi Coast, Italy
The beaches and the sea of Meta di Sorrento small village near Sorrento in Italy.
Photo of Marina Di Puolo beautiful beach In Sorrento, Italy.
Photo of Colorful view over the beach at Amalfi, Italy.
Photo of beach chairs and umbrella on a breakwater in Sorrento, Italy.
Photo of beautiful beachside in Sorrento Peninsula, the front of the Isle of Capri, Italy.
Photo of Sorrento beautiful beach in Italy with view of the jetties lined with beach huts and sun shades by the sea.
Photo of view from Sorrento, Italy at dusk from a flower draped terrace.
Colosseum, Rome, Italy.
Photo of piazza de spagna in Rome, Italy.
Photo of Fountain di Trevi in Rome, Italy.
Bridge Il Tevere a Ponte Vittorio Emanuele II in Rome, Italy.
Hadrian Mausoleum, Rome, Italy.
 Vatican dome of San Pietro and Sant Angelo Bridge, over Tiber river in Rome, Italy.
panoramic view of Rome and St. Peter's Basilica, Italy.
View of Pantheon in the morning, Rome, Italy.
Rome, Italy. Stunning twilight view of Forum ancient ruins, seen from Capitoline hill with Colosseum in background.
Aerial view of forum romanum and surrounding areas of historical centre of italian capital rome.
Cozy old street in Trastevere in Rome, Italy. Trastevere is rione of Rome, on the west bank of the Tiber in Rome, Lazio, Italy. Architecture and landmark of Rome.
Aerial panorama of St. Peter's Square in Vatican with Rome in the background. Italy.
photo of view of Illuminated Fontana Di Trevi, Trevi Fountain at Dusk, Rome, Italy.
photo of view of Spanish Step, Rome, Italy.
photo of view of Museum Luasanne, Rome, Italy.
photo of view Roma Wall of Lugo, Rome, Italy.
photo of view of Roman Bridge Cordoba, Rome, Italy.
photo of view of Roman ruins in Rome, Forum, Rome, Italy.
photo of view of Roman Bridge of Cordoba, Rome, Italy.
photo of view of The Iconic, the legendary Coliseum of Rome, Italy.
photo of view of Rome, Italy: The Roman Forum, Latin: Forum Romanum, Italian: Foro Romano, Rome, Italy.
photo of view of Trevi Fountain (Fontana di Trevi) in Rome, Italy. Trevi is most famous fountain of Rome. Architecture and landmark of Rome, Postcard of Rome, Italy.
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Escape the ordinary with this exciting 6-day road trip through Italy. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Brindisi, 1 night in Sorrento, and 1 night in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Brindisi, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Pantheon are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Piazza Navona, learn more about the unique Amalfi Coast, and immerse yourself in the vibrant atmosphere of Spanish Steps.

As you hit the open road and drive through Brindisi, Matera, Alberobello, Positano, Amalfi, Ravello, Sorrento, Pompei, Ottaviano, and Rome, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Swabian Castle of Brindisi
Sassi di MateraCasa Grotta del CasalnuovoTrulli di Alberobello PugliaColonne Romane
Chiesa di Santa Maria AssuntaAmalfi CoastVilla Rufolo
Archaeological Park of PompeiiMount VesuviusPiazza Navona
PantheonTrevi FountainSpanish Steps
Palazzo Granafei Nervegna (Brindisi)

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Day 1

Day 1

  • Brindisi - Arrival day
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  • Swabian Castle of Brindisi
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Welcome to Brindisi, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 2 nights immersing yourself in Brindisi's charm before embarking on the next leg of your journey.

Brindisi is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Swabian Castle Of Brindisi, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Brindisi. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brindisi, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Bracerie Escosazio, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Penny is another top choice with a popular menu. You could also check for a table at Piadineria. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Brindisi tonight.

Keep the evening going at Peddy Bar. Pasticceria. Gelateria. Happyhour. Prodotti Celiaci. Slot Machines. Scommesse, a great choice for enjoying the after-dinner hours with a drink. You could also go to Eden Cafè, which offers a similarly pleasant setting and great drinks.

Raise a toast to the start of your 6-day road trip in Italy!

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Day 2

Day 2

  • Brindisi
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Drive 305 km, 4 hours 25 min

  • Sassi di Matera
  • Casa Grotta del Casalnuovo
  • Trulli di Alberobello Puglia
  • Colonne Romane
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Greet day 2 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Brindisi for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Matera, Alberobello, and Brindisi.

A blend of family-friendly attractions, romantic experiences, and scenic views await you in Brindisi on today’s itinerary. First up is the well-known archeological site, Sassi Di Matera. Afterward, continue to Casa Grotta Del Casalnuovo, a cave every traveler should visit.

As you explore Brindisi’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Trulli Di Alberobello Puglia. This notable historical landmark is an essential stop. Following that, head to End Of The Via Appia Antica, another must-visit site that will enhance your experience.

When you’re done exploring for the day, you’ll return to Brindisi and your accommodation.

Indulge in a memorable dining experience at one of Brindisi's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a delicious meal at Betty - Gelateria Cafe Ristorante Pizzeria a Brindisi, a top-rated dining destination in Brindisi. If you're in the mood to try something new, consider Bento, another top spot with a mouthwatering menu. You might also want to secure a reservation at Cozza Nera. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Brindisi this evening.

Continue your evening by exploring the vibrant nightlife scene at Altair Cafè, a prime destination for a thrilling night out.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

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Day 3

Day 3

  • Brindisi
  • Sorrento
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Drive 475 km, 7 hours 22 min

  • Chiesa di Santa Maria Assunta
  • Amalfi Coast
  • Villa Rufolo
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On day 3 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Positano, Amalfi, and Ravello. In the evening, you’ll end up in Sorrento, where you will stay for 1 night.

Start your day with a visit to Chiesa Di Santa Maria Assunta. This locally appreciated church is a must-visit in the village.

One of the best things about exploring Brindisi on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Villa Rufolo, a captivating historical landmark in the village.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Sorrento. Sorrento offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Sorrento. If you are looking to dine at a popular restaurant in the town, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Frankie's Pizza Bar Sorrento Brunch & Vegan, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Bougainvillea? It's another excellent option with a diverse menu. Consider reserving a table at Banana Split as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Sorrento.

Extend your evening after a delightful meal by visiting Leone Rosso Café, which offers the perfect atmosphere for a night out. Moreover, Hotel Antiche Mura Sorrento is another popular option for a drink or two.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 4

Day 4

  • Sorrento
  • Rome
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Drive 293 km, 4 hours 35 min

  • Archaeological Park of Pompeii
  • Mount Vesuvius
  • Piazza Navona
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Embark on another extraordinary experience on day 4 of your road trip in Italy. Today, you will make 3 stops and experience some of the highlights of Pompei, Ottaviano, and Rome. At the end of the day, you will enjoy the comforts of a top-rated hotel in Rome, which will be your home away from home for 1 night.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Sorrento allows for both. Start by heading to Archaeological Park Of Pompeii. This well-known archeological site provides an insightful glimpse into the town's identity. Next, discover Mount Vesuvius, a picturesque volcano, promising a delightful encounter.

Continue your sightseeing with a visit to Piazza Navona, a timeless public square.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Treat yourself to a delicious dinner at La Bottega Roma, an excellent option for tonight's dining. Looking for something different? Pasta In Corso offers a tantalizing alternative with its diverse menu. And don’t miss Trattoria Vecchia Roma. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Rome.

Following your dinner, dive into the local bar culture at La Botticella Of Poggi Giovanni. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Almalu Trastevere, the perfect place for those looking to experience the best of the nightlife. Similarly, Bar Viminale Di Pepi Maurilio provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

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Day 5

Day 5

  • Rome
  • Brindisi
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Drive 623 km, 6 hours 40 min

  • Pantheon
  • Trevi Fountain
  • Spanish Steps
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On day 5 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Rome. When you’re not sightseeing, take time to relax at your selected hotel in Brindisi, where you’ll be staying for 1 night.

Savor the day by visiting some of the best places to see in Rome, including a monument and a public square. Start your adventure at Pantheon. This timeless monument is a must-visit for travelers looking for a unique holiday experience. Make your way to Trevi Fountain located in Rome for another exciting encounter.

Next, immerse yourself in the setting of Spanish Steps. Its culturally significant features will captivate you.

At the end of the day, you will drive to Brindisi, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Brindisi. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely meal at Rendez-Vous Cafè Bistrot, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Pizzeria La Nassa is another top choice with a popular menu. You could also check for a table at Birreria 64. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Brindisi tonight.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 6

Day 6

  • Brindisi - Departure day
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  • Palazzo Granafei Nervegna (Brindisi)
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Day 6 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Brindisi before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Palazzo Granafei Nervegna (brindisi), a history-steeped palace before you head out.

Maximize your last day in Italy and go on a shopping spree in Brindisi’s shopping center. Browse for souvenirs to remind you of your wonderful journey in Italy.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Brindisi.

Enjoy a lovely meal at Supermercato Famila, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Break24 is another top choice with a popular menu.

You’ll then say farewell to Brindisi. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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