6-Day Italy Self-Drive Road Trip With Itinerary from Pescara to Rome and Florence

At the end of the day, you'll drive back to Rome, where you'll stay for 1 night more.

Vatican Museums is must-visit art museum and a great starting point for the day. Next, continue your journey to Sistine Chapel, a top-rated chapel, located just a leisurely stroll away. Next, head to Trevi Fountain, a symbolic monument, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Rome. When you're ready, let your sightseeing route take you to the world-famous Piazza Di Spagna. If you’re looking for more, Spanish Steps is also an extraordinary attraction that is worthwhile a visit. Lastly, don’t miss Villa Borghese, a place of mesmerizing interest in the city.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a wonderful meal at RomAntica, a top-rated dining spot in Rome. If you're in the mood for something new, try Coso Ristorante, another premier location with a delectable menu. You might also want to book a table at DEROMA - Farine Romane. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.

After enjoying a fulfilling meal, continue your evening at Sant' Eustachio Caffè, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Yellowsquare Rome offers a welcoming atmosphere for easing into the nightlife. Similarly, Caffè Portofino provides an excellent environment for a relaxed and enjoyable evening.

Head back to your accommodation in Rome and get some rest in preparation for another magical day of your road trip in Italy!

On day 4 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Florence. In the evening, you’ll end up in Florence, where you will stay for 1 night.

Rome is home to plenty of attractions that offer fun adventures, photo-friendly spots, and historic treasures! Start at Basilica Of Santa Croce In Florence, a well-known church that is worthwhile a visit in the city. Nearby, you’ll find Uffizi Gallery, enchanting visitors with its instagrammable appeal. Continue your exploration at Ponte Vecchio. This historical landmark is one of the city’s most world-famous spots.

Enjoy the freedom of exploring Rome at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Piazza Della Repubblica. After exploring the public square, head to the widely recognized Cathedral Of Santa Maria Del Fiore. Lastly, wrap up today’s self-guided sightseeing tour with a visit to Piazza Della Signoria, a place of visually striking interest in Rome.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a wonderful meal at Ristorante Oliviero 1962, a top-rated dining spot in Florence. If you're in the mood for something new, try Di Poneta Novoli, another premier location with a delectable menu. You might also want to book a table at Caffe San Firenze. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

Explore the vibrant nightlife at Manifattura after your meal, a hub for lively evenings and memorable moments. Or, head to Se·sto On Arno Rooftop Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Il Vinile is perfect for those looking to extend their night with a touch of local flavor.

Raise your glass to another unforgettable day in Italy!

Embark on another extraordinary experience on day 5 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Siena. At the end of the day, you will enjoy the comforts of a top-rated hotel in Pescara, which will be your home away from home for 1 night.

Get ready for a day filled with fun adventures, scenic views, and photo-friendly spots in the charming city of Florence. Your adventure starts at Fortezza Medicea (siena), an intriguing local hot spot. Another notable attraction to explore is Basilica Of San Domenico. This intriguing church is known for its instagrammable appeal.

After soaking in the highlights of these sights, take some time to wander Florence's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Siena Cathedral. This visually striking church offers a fascinating experience that many visitors find memorable. Piazza Del Campo is also worth visiting.

At the end of the day, you will drive to Pescara, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Pescara. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Ciacco, a highly-rated dining destination in Pescara. If you're eager to try something different, consider Bar Sara, another top spot with a tantalizing menu. You might also want to secure a reservation at Ristorante Franco. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Pescara this evening.

After savoring a delicious meal, step into the vibrant nightlife at Bar Napoli, where the evening is just getting started. In the same way, Bar Supermarket offers a unique charm perfect for experiencing the local bar scene in Pescara. Post Bar is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Savor another day of unforgettable experiences in Italy!