7-Day Italy Self-Drive Road Trip With Itinerary from Brindisi to Matera, Naples, Rome, and Santa Maria degli Angeli
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Experience the freedom of the open road in Italy as you embark on an unforgettable 7-day road trip! This experience caters to every traveler, featuring destinations like Brindisi, Matera, Naples, Pompei, Rome, Santa Maria degli Angeli, and Alberobello.
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Brindisi, 1 night in Matera, 1 night in Naples, 1 night in Rome, and 1 night in Santa Maria degli Angeli. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Brindisi, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.
As you hit the open road and drive through Brindisi, Matera, Naples, Pompei, Rome, Santa Maria degli Angeli, and Alberobello, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
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Day 1
- Brindisi - Arrival day
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- Lungomare Regina Margherita
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Say hello to Brindisi! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Brindisi for 1 night before you continue your adventure!
Brindisi is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Amici Dei Musei Brindisi, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Brindisi. Make yourself at home and enjoy some downtime before heading out again.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brindisi, it's often a good idea to reserve a table in advance.
Enjoy a delicious meal at Bracerie Escosazio, a highly-rated dining destination in Brindisi. If you're eager to try something different, consider Penny, another top spot with a tantalizing menu. You might also want to secure a reservation at Piadineria. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Brindisi this evening.
Following your dinner, dive into the local bar culture at Peddy Bar. Pasticceria. Gelateria. Happyhour. Prodotti Celiaci. Slot Machines. Scommesse. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Eden Cafè, the perfect place for those looking to experience the best of the nightlife. Similarly, Altair Cafè provides excellent drinks and a great atmosphere, ensuring a memorable night out.
Raise a toast to the start of your 7-day road trip in Italy!
Day 2
- Brindisi
- Matera
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Drive 156 km, 2 hours 25 min
- Belvedere di Piazza Giovanni Pascoli
- Sassi di Matera
- Casa Noha
- Cattedrale di Maria Santissima della Bruna e Sant'Eustachio
- Church of Saint Peter 'Barisano'
- Palombaro lungo
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Experience an unparalleled adventure on day 2 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Matera. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Matera. You will spend 1 night here for some well-deserved relaxation.
Get ready for a day filled with family-friendly attractions, romantic experiences, and breathtaking views in the charming city of Brindisi. Your adventure starts at Belvedere Di Piazza Giovanni Pascoli, a frequently visited local hot spot. Another notable attraction to explore is Sassi Di Matera. This captivating archeological site is known for its enchanting appeal.
After soaking in the highlights of these sights, take some time to wander Brindisi's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Casa Noha. This eye-catching museum offers a fascinating experience that many visitors find memorable. Cattedrale Di Maria Santissima Della Bruna E Sant'eustachio is also worth visiting, along with Church Of Saint Peter 'barisano'. These standout landmarks offer unique experiences that add to the day’s enjoyment. End your day at Palombaro Lungo. This underrated cave system provides a fitting finale to your sightseeing.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Matera. Matera offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
After a day of adventure, treat yourself to an exquisite dinner at one of Matera's best restaurants.
Enjoy a delicious meal at Ristorante Le Bubbole, a top-rated dining destination in Matera. If you're in the mood to try something new, consider Baccanti, another top spot with a mouthwatering menu.
Head back to your accommodation in Matera and get some rest in preparation for another magical day of your road trip in Italy!
Day 3
- Matera
- Naples
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Drive 311 km, 4 hours 12 min
- Naples National Archaeological Museum
- piazza del Plebiscito
- Archaeological Park of Pompeii
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On day 3 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Naples and Pompei. In the evening, you’ll end up in Naples, where you will stay for 1 night.
Matera is home to plenty of attractions that offer fun adventures, picturesque spots, and history-rich sites! Start at Naples National Archaeological Museum, an interesting museum that is worthwhile a visit in the city. Nearby, you’ll find Piazza Del Plebiscito, enchanting visitors with its visually striking appeal. Continue your exploration at Archaeological Park Of Pompeii. This archeological site is one of the city’s most locally renowned spots.
When you’re done exploring for the day, you’ll drive to your hotel in Naples. Check in and spend some time relaxing before you head out to tour the city.
As dinnertime approaches, it's time to head out for a bite to eat in Naples. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Make sure to reserve a table at L'Oca Nera Irish Pub, an iconic dining spot in Naples. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Mimì alla Ferrovia, a popular restaurant in Naples. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Spuzzulè Winebar, a hidden gem nestled in Naples. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
If you’re not ready to end the night just yet, Happening Cocktail Bar offers a perfect venue to relax and savor a drink. Similarly, Shanti Art Musik Bar is well-suited for those looking to unwind in a social setting. Gran Caffè Gambrinus is another excellent spot to enjoy a nightcap after a delightful meal.
Raise your glass and celebrate another amazing day of your road trip in Italy!
Day 4
- Naples
- Rome
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Drive 237 km, 3 hours 7 min
- Colosseum
- Roman Forum
- St Peter's Basilica
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Dive into day 4 of your remarkable road trip in Italy. Today you will explore Rome and Vatican City, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Rome. You’ll stay here for 1 night.
Start your adventure at Colosseum. This world-famous archeological site is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the breathtaking wonders of Roman Forum, a must-see archeological site in the city.
Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to St. Peter's Basilica. This wondrous major basilica offers an enriching experience. These sights offer a fulfilling end to a perfect day.
At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Enjoy a delicious meal at La Bottega Roma, a highly-rated dining destination in Rome. If you're eager to try something different, consider Pasta In Corso, another top spot with a tantalizing menu. You might also want to secure a reservation at Trattoria Vecchia Roma. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.
Following your dinner, dive into the local bar culture at La Botticella Of Poggi Giovanni. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Almalu Trastevere, the perfect place for those looking to experience the best of the nightlife. Similarly, Bar Viminale Di Pepi Maurilio provides excellent drinks and a great atmosphere, ensuring a memorable night out.
Raise your glass to another unforgettable day in Italy!
Day 5
- Rome
- Assisi
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Drive 189 km, 3 hours 19 min
- Circus Maximus
- Piazza Navona
- Pantheon
- Trevi Fountain
- Spanish Steps
- Villa Borghese
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Embark on another extraordinary experience on day 5 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Rome. At the end of the day, you will enjoy the comforts of a top-rated hotel in Santa Maria degli Angeli, which will be your home away from home for 1 night.
Today's adventure in Rome promises more breathtaking discoveries and enriching experiences! Begin at Circus Maximus. This picture-perfect archeological site is a highlight of any visit in the city. Then, enjoy Piazza Navona, another history-steeped attraction that never fails to captivate visitors. Next, head over to Pantheon, one of the city’s most iconic attractions, known for its monumental features.
If you’re looking for more, spend time soaking in the atmosphere of Trevi Fountain. This enchanting monument is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Spanish Steps, an astonishing public square, and take a stroll around the area. If you want to extend your self-guided sightseeing tour, go check out Villa Borghese before you head back to your hotel.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Santa Maria degli Angeli. Santa Maria degli Angeli offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Santa Maria degli Angeli. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Let the evening flow smoothly from dinner to drinks at Bibenda Assisi Wine Tasting & Gourmet Food, Olive Oil And Chocolate Tastings, a top-rated bar in the area.
Celebrate another amazing day of your road trip adventure in Italy!
Day 6
- Assisi
- Brindisi
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Drive 676 km, 7 hours 18 min
- Church of Santa Maria sopra Minerva in Assisi
- Chiesa Nuova di San Francesco Convertito
- Trulli di Alberobello Puglia
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On day 6 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Santa Maria degli Angeli and Alberobello. When you’re not sightseeing, take time to relax at your selected hotel in Brindisi, where you’ll be staying for 1 night.
Get ready for an exciting day in Santa Maria degli Angeli. Today’s sightseeing agenda includes a church and a historical landmark. Begin your adventure at Church Of Santa Maria Sopra Minerva In Assisi. This is a curiosity-inducing church you should not miss. Another must-see is Chiesa Nuova Di San Francesco Convertito, an intriguing church in Santa Maria degli Angeli.
When you’re ready for the next sight, head to Trulli Di Alberobello Puglia.
When you’re done exploring for the day, you’ll drive to your hotel in Brindisi. Check in and spend some time relaxing before you head out to tour the city.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Brindisi. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Treat yourself to a delightful dinner at Betty - Gelateria Cafe Ristorante Pizzeria a Brindisi, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Bento? It's another excellent option with a diverse menu. Consider reserving a table at Cozza Nera as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Brindisi.
Relax and recharge in preparation for another adventurous day in Italy!
Day 7
- Brindisi - Departure day
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- Saint Pietro of Schiavoni Archeologica Area
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Day 7 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Brindisi before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, begin at Saint Pietro Of Schiavoni Archeologica Area. This curiosity-inducing archeological site is a popular place to see in the city.
Maximize your last day in Italy and go on a shopping spree in Brindisi’s shopping center. Browse for souvenirs to remind you of your wonderful journey in Italy.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Brindisi.
Treat yourself to a delightful dinner at Rendez-Vous Cafè Bistrot, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Pizzeria La Nassa? It's another excellent option with a diverse menu.
You’ll then say farewell to Brindisi. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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