One-Week Italy Self-Drive Road Trip With Itinerary from Perugia traveling south to Rome

Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Santa Maria degli Angeli. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Rome. You will spend 4 nights here for some well-deserved relaxation.

Today, you'll explore some of the most beautiful places in Perugia, including a church and a public square. Start your day with a visit to Basilica Of San Francesco D'assisi. This notable church is a must-visit in the town. When you’re ready for your next discovery, continue to Piazza Del Comune, which may be one of the most romantic places you will experience today.

One of the best things about exploring Perugia on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Cathedral Of San Rufino, an underrated church in the town. If you’re up for more discoveries, don’t forget to reserve some time for Basilica Di Santa Chiara.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy an outstanding dining experience at La Pergola, a 3-star Michelin restaurant offering an exceptional mediterranean and contemporary menu. Alternatively, if you're in the mood for something different, consider the nearby 2-star Michelin-awardee, Il Pagliaccio, known for its delicious creative and innovative cuisine. Another highly-recommended place to eat in Rome is Enoteca La Torre, a renowned restaurant with a 2-star Guide Michelin recognition and a delicious mediterranean and creative menu.

Continue your evening by exploring the vibrant nightlife scene at La Botticella Of Poggi Giovanni, a prime destination for a thrilling night out. Also, don’t forget to check out Almalu Trastevere, a bar that offers unique local touches. Likewise, Bar Viminale Di Pepi Maurilio provides an excellent alternative for a fun evening.

Relax and recharge in preparation for another adventurous day in Italy!

On day 4 of your road trip, you’ll start and end your day in Rome, where you'll stay for 3 nights more.

Make sure to visit Trastevere, a popular neighborhood in Vatican City. Spend some time wandering around the area and soak in its distinctive charm. You’ll also discover that several of the city’s must-see attractions are just around the corner.

When you’re ready, kick off your sightseeing adventure at Vatican Museums. This globally renowned art museum is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Sistine Chapel, one of the city’s best highlights.

Next, check out St. Peter's Basilica, one of the most globally renowned places to see in Rome. This major basilica is a favorite among locals and travelers alike.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Make sure to reserve a table at RomAntica, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Coso Ristorante, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of DEROMA - Farine Romane, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your meal, keep the night alive at a bar like Sant' Eustachio Caffè, known for its lively atmosphere. Yellowsquare Rome is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Caffè Portofino offers an excellent atmosphere for those looking to amp up the evening.

Savor another day of unforgettable experiences in Italy!

Day 6 offers a multitude of experiences. You will stay in Rome for 1 night more, offering you enough time to explore at a relaxed pace.

Via del Corso is a fantastic place you can explore today in Rome. This street is a testament to the city’s character, and it's easy to spend hours just walking around and admiring the surroundings. Soak in the Rome-way-of-life and visit all the nearby sights. You should also check out Via dei Condotti, a street offering more opportunities to enjoy the city’s vibrant atmosphere and landmarks.

Get ready for a day filled with fun adventures, romantic experiences, and scenic views in the charming city of Rome. Your adventure starts at Piazza Del Popolo, a famous local hot spot. Another notable attraction to explore is Piazza Di Spagna. This iconic public square is known for its romantic appeal.

After soaking in the highlights of these sights, take some time to wander Rome's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Trevi Fountain. This enchanting monument offers a fascinating experience that many visitors find memorable.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at Sofitel Roma Villa Borghese, a top-rated dining spot in Rome. If you're in the mood for something new, try Centro, another premier location with a delectable menu. You might also want to book a table at Ristorante Tema. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.

Get a good night's sleep and look forward to another great day on the road in Italy!

On day 7 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Orvieto. When you’re not sightseeing, take time to relax at your selected hotel in Perugia, where you’ll be staying for 1 night.

Get ready for an exciting day in Rome. Today’s sightseeing agenda includes a church, a cave system, and a monument. Begin your adventure at Orvieto Cathedral. This is an interesting church you should not miss. Another must-see is Orvieto Underground, an increasingly popular cave system in Rome.

When you’re ready for the next sight, head to Well Of St. Patrick.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Perugia. Perugia offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Perugia. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Perugia Plaza Hotel, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Elfo Pub Perugia? It's another excellent option with a diverse menu. Consider reserving a table at Sangallo Palace Hotel as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Perugia.

If you’re not ready to end the night just yet, Il Birrino offers a perfect venue to relax and savor a drink. Similarly, Quei Bravi Ragazzi is well-suited for those looking to unwind in a social setting. Lo Chalet - Lounge Bar is another excellent spot to enjoy a nightcap after a delightful meal.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!