One-Week Italy Self-Drive Road Trip With Itinerary from Pescara traveling west to Rome, Florence, and Santa Maria degli Angeli

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Explore the best of Italy on a 8-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Pescara, Rome, Florence, Pisa, Siena, Santa Maria degli Angeli, and Gubbio. This road trip itinerary in Italy seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Pescara, 2 nights in Rome, 2 nights in Florence, and 1 night in Santa Maria degli Angeli. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Pescara, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.

As you hit the open road and drive through Pescara, Rome, Florence, Pisa, Siena, Santa Maria degli Angeli, and Gubbio, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Locomotiva FS 740351
ColosseumRoman ForumPantheonSpanish StepsPiazza di SpagnaTrevi Fountain
Vatican MuseumsSistine ChapelSt Peter's BasilicaPiazza NavonaTrastevereVia del Corso
Basilica of Santa Croce in FlorenceUffizi GalleryPonte VecchioPiazza della RepubblicaCathedral of Santa Maria del Fiorepiazza della Signoria
Piazza del Duomo, PisaLeaning Tower of PisaThe Boboli Gardenspiazzale MichelangeloOltrarno
Fortezza MediceaSiena Cathedralpiazza del CampoPorta PispiniBasilica of San Francesco d'AssisiPiazza del Comune
Basilica of Sant'Ubaldo, GubbioFunivia Colle ElettoPalazzo dei ConsoliChiesa di San FrancescoGola Del Bottaccione Gubbio
Parrocchia Spirito Santo

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Day 1

Day 1

  • Pescara - Arrival day
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  • Locomotiva FS 740351
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Your road trip adventure in Italy begins as soon as you reach Pescara and pick up your car. You’ll stay in Pescara for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Pescara is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Locomotiva Fs 740.351, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Pescara. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Pescara, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Taverna 58, an iconic dining spot in Pescara. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante Carlo Ferraioli, a popular restaurant in Pescara. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Sesamo Nero, a hidden gem nestled in Pescara. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After savoring a delicious meal, step into the vibrant nightlife at Posa Caffè Pescara, where the evening is just getting started. In the same way, Bar Mixer offers a unique charm perfect for experiencing the local bar scene in Pescara. Temple Bar Irish Pub is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise a toast to the start of your 8-day road trip in Italy!

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Day 2

Day 2

  • Pescara
  • Rome
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Drive 214 km, 3 hours 27 min

  • Colosseum
  • Roman Forum
  • Pantheon
  • Spanish Steps
  • Piazza di Spagna
  • Trevi Fountain
  • More

On day 2 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Rome. In the evening, you’ll end up in Rome, where you will stay for 2 nights.

Today’s agenda in Pescara includes an archeological site, a monument, and a public square. Colosseum is must-visit archeological site and a great starting point for the day. Next, continue your journey to Roman Forum, a wondrous archeological site, located just a leisurely stroll away. Next, head to Pantheon, a heritage-rich monument, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Pescara. When you're ready, let your sightseeing route take you to the extraordinary Spanish Steps. If you’re looking for more, Piazza Di Spagna is also a timeless attraction that is worthwhile a visit. Lastly, don’t miss Trevi Fountain, a place of detailed interest in the city.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Don’t miss out on dining at La Bottega Roma, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Pasta In Corso, another top spot with a mouthwatering menu. You might also want to secure a reservation at Trattoria Vecchia Roma. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Continue your evening by exploring the vibrant nightlife scene at La Botticella Of Poggi Giovanni, a prime destination for a thrilling night out. Also, don’t forget to check out Almalu Trastevere, a bar that offers unique local touches. Likewise, Bar Viminale Di Pepi Maurilio provides an excellent alternative for a fun evening.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

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Day 3

Day 3

  • Rome
  • More

Drive 8 km, 55 min

  • Vatican Museums
  • Sistine Chapel
  • St Peter's Basilica
  • Piazza Navona
  • Trastevere
  • Via del Corso
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Greet day 3 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Rome for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Vatican City and Rome.

Don’t miss Trastevere in Vatican City today, a must-see neighborhood that offers a glimpse into the city’s vibrant character. Take your time to explore its best features, and enjoy the convenience of nearby top-rated landmarks. While you’re in the area, consider visiting Via del Corso, another street that adds to the charm of Vatican City.

Get ready for a day filled with fun adventures, romantic experiences, and scenic views in the charming city of Rome. Your adventure starts at Vatican Museums, a wondrous local hot spot. Another notable attraction to explore is Sistine Chapel.

After soaking in the highlights of these sights, take some time to wander Rome's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to St. Peter's Basilica. Piazza Navona is also worth visiting.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delightful dinner at RomAntica, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Coso Ristorante? It's another excellent option with a diverse menu. Consider reserving a table at DEROMA - Farine Romane as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

Round off your dining experience by visiting Sant' Eustachio Caffè, a prime location for a drink. Alternatively, explore the distinctive characteristics of Yellowsquare Rome, a bar catering to every mood and preference. Caffè Portofino likewise offers a unique atmosphere, perfect for a memorable night out.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

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Day 4

Day 4

  • Rome
  • Florence
  • More

Drive 276 km, 3 hours 31 min

  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • Piazza della Repubblica
  • Cathedral of Santa Maria del Fiore
  • piazza della Signoria
  • More

Embark on another extraordinary experience on day 4 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Florence. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 2 nights.

Brace yourself for today’s incredible lineup of attractions in Rome, featuring fun adventures, picturesque spots, and historic treasures. Start at Basilica Of Santa Croce In Florence, a notable church in the city. Then, head to Uffizi Gallery and soak in the ambiance of this romantic art gallery.

There are many interesting places to see in Rome, and when you are ready for more, go to Ponte Vecchio. This is one of the city’s most globally renowned enchanting spots of interest. After exploring the historical landmark, visit the notable Piazza Della Repubblica. Not far away, you'll also find Cathedral Of Santa Maria Del Fiore. This church is a romantic highlight in Rome. Before wrapping up your self-guided sightseeing tour, head to Piazza Della Signoria, a widely recognized public square in the city.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Savor the flavors at Ristorante Oliviero 1962, a top pick for dinner tonight. Alternatively, Di Poneta Novoli beckons with its unique menu offerings. Also, consider Caffe San Firenze. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.

If you’re not ready to end the night just yet, Manifattura offers a perfect venue to relax and savor a drink. Similarly, Se·sto On Arno Rooftop Bar is well-suited for those looking to unwind in a social setting. Il Vinile is another excellent spot to enjoy a nightcap after a delightful meal.

Raise your glass to another unforgettable day in Italy!

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Day 5

Day 5

  • Florence
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Drive 177 km, 2 hours 54 min

  • Piazza del Duomo, Pisa
  • Leaning Tower of Pisa
  • The Boboli Gardens
  • piazzale Michelangelo
  • Oltrarno
  • More

On day 5 of your road trip, you’ll start and end your day in Florence, where you'll stay for 1 night more.

A visit to Oltrarno in Pisa is a must on the agenda today. This neighborhood is full of hidden gems and character, perfect for a leisurely stroll. Plus, you’ll be close to some of the city’s most famous sights.

Brace yourself for today’s incredible lineup of attractions in Florence, featuring family-friendly attractions, breathtaking views, and photo-friendly spots. Start at Piazza Del Duomo, Pisa, a timeless public square in the city. Then, head to Leaning Tower Of Pisa and soak in the ambiance of this UNESCO world heritage-listed monument.

There are many interesting places to see in Florence, and when you are ready for more, go to The Boboli Gardens. This is one of the city’s most well-known romantic spots of interest. After exploring the botanical garden, visit the extraordinary Piazzale Michelangelo.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Make sure to reserve a table at Ditta Artigianale, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Trattoria Da Burde, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Casa Toscana, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a fulfilling meal, continue your evening at Bar 50 Rosso, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Bitter Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Archea Brewery provides an excellent environment for a relaxed and enjoyable evening.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 6

Day 6

  • Florence
  • Assisi
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Drive 200 km, 3 hours 36 min

  • Fortezza Medicea
  • Siena Cathedral
  • piazza del Campo
  • Porta Pispini
  • Basilica of San Francesco d'Assisi
  • Piazza del Comune
  • More

On day 6 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Siena and Santa Maria degli Angeli. When you’re not sightseeing, take time to relax at your selected hotel in Santa Maria degli Angeli, where you’ll be staying for 1 night.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Florence allows for both. Start by heading to Fortezza Medicea (siena). This increasingly popular monument provides an insightful glimpse into the city's identity. Next, discover Siena Cathedral, an enchanting church, promising a delightful encounter.

Continue your sightseeing with a visit to Piazza Del Campo, a widely recognized public square. When you’re done, don’t forget to make a stop at the underrated Porta Pispini. Not far away from the historical landmark, you will find the visually striking Piazza Del Comune, perfect for a quick visit. Round off your day at Basilica Of San Francesco D'assisi, another gem in Florence with picture-perfect features to discover.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Santa Maria degli Angeli. Santa Maria degli Angeli offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Santa Maria degli Angeli. If you are looking to dine at a popular restaurant in the town, it's often a good idea to reserve a table in advance.

With its reputation for pleasing customers, it’s a fantastic choice for tonight in Santa Maria degli Angeli.

Extend your evening after a delightful meal by visiting Bibenda Assisi Wine Tasting & Gourmet Food, Olive Oil And Chocolate Tastings, which offers the perfect atmosphere for a night out.

Head back to your accommodation in Santa Maria degli Angeli and get some rest in preparation for another magical day of your road trip in Italy!

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Day 7

Day 7

  • Assisi
  • Pescara
  • More

Drive 318 km, 5 hours 19 min

  • Basilica of Sant'Ubaldo, Gubbio
  • Funivia Colle Eletto
  • Palazzo dei Consoli
  • Chiesa di San Francesco
  • Gola Del Bottaccione Gubbio
  • More

Experience an unparalleled adventure on day 7 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Gubbio. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Pescara. You will spend 1 night here for some well-deserved relaxation.

Today's adventure in Santa Maria degli Angeli promises more breathtaking discoveries and enriching experiences! Begin at Basilica Of Sant'ubaldo, Gubbio. This awe-inspiring church is a highlight of any visit in the town. Then, enjoy Funivia Colle Eletto, another breathtaking attraction that never fails to captivate visitors. Next, head over to Palazzo Dei Consoli, one of the town’s most up-and-coming attractions, known for its respected features.

If you’re looking for more, spend time soaking in the atmosphere of Chiesa Di San Francesco. This photogenic church is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Gola Del Bottaccione, an up-and-coming canyon, and take a stroll around the area.

When you’re done exploring for the day, you’ll drive to your hotel in Pescara. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Pescara. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Dine in style at Ciacco, a top recommendation for dinner tonight. Or, for a change of pace, Bar Sara boasts a menu that's sure to impress. Also, be sure to check out Ristorante Franco. Known as a local hotspot, it’s a great choice for tonight in Pescara.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Bar Napoli, a well-loved spot among locals and tourists. Or, head to Bar Supermarket. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Post Bar, another top-rated place in the area.

Say good night to Pescara and look forward to another great day of your road trip in Italy!

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Day 8

Day 8

  • Pescara - Departure day
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  • Parrocchia Spirito Santo
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Day 8 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Pescara before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Parrocchia Spirito Santo. This beloved church is a popular place to see in the city.

As your final day in Italy unfolds, enjoy a last-minute shopping spree in Pescara's best shopping area, Centro Commerciale Pescara Porta Nuova. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Italy.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Pescara.

If you're in the mood to try something new, consider La Taverna Antica, another top spot with a mouthwatering menu.

You’ll then say farewell to Pescara. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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