6-Day Italy Self-Drive Road Trip With Itinerary from Pescara to Rome and Florence
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Explore the best of Italy on a 6-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Pescara, Rome, Florence, and Siena. This road trip itinerary in Italy seamlessly combines exploration with relaxation.
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Pescara, 2 nights in Rome, and 1 night in Florence. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Pescara, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of Vatican Museums.
As you hit the open road and drive through Pescara, Rome, Florence, and Siena, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
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Day 1
- Pescara - Arrival day
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- Ponte del Mare
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Welcome to Pescara, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 1 night immersing yourself in Pescara's charm before embarking on the next leg of your journey.
Pescara is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ponte Del Mare, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Find your way to your hotel in Pescara. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Pescara, it's often a good idea to reserve a table in advance.
Enjoy a lovely meal at Taverna 58, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Ristorante Carlo Ferraioli is another top choice with a popular menu. You could also check for a table at Sesamo Nero. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Pescara tonight.
Keep the excitement of the evening going by visiting a bar or two. Posa Caffè Pescara is an excellent place to start. You could also check out Bar Mixer, offering a different kind of charm. A last recommendation for the day is Temple Bar Irish Pub. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.
Raise a toast to the start of your 6-day road trip in Italy!
Day 2
- Pescara
- Rome
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Drive 212 km, 3 hours 7 min
- Colosseum
- Roman Forum
- Pantheon
- Piazza Navona
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On day 2 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Rome. In the evening, you’ll end up in Rome, where you will stay for 2 nights.
Pescara is home to plenty of attractions that offer family-friendly attractions, breathtaking views, and picturesque spots! Start at Colosseum, an iconic archeological site that is worthwhile a visit in the city. Nearby, you’ll find Roman Forum, enchanting visitors with its culturally significant appeal. Continue your exploration at Pantheon. This monument is one of the city’s most globally renowned spots.
Enjoy the freedom of exploring Pescara at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Piazza Navona.
When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Treat yourself to a wonderful meal at La Bottega Roma, a top-rated dining spot in Rome. If you're in the mood for something new, try Pasta In Corso, another premier location with a delectable menu. You might also want to book a table at Trattoria Vecchia Roma. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.
Following your dinner, dive into the local bar culture at La Botticella Of Poggi Giovanni. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Almalu Trastevere, the perfect place for those looking to experience the best of the nightlife. Similarly, Bar Viminale Di Pepi Maurilio provides excellent drinks and a great atmosphere, ensuring a memorable night out.
Say good night to Rome and look forward to another great day of your road trip in Italy!
Day 3
- Rome
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Drive 15 km, 1 hour 20 min
- Vatican Museums
- Sistine Chapel
- Trevi Fountain
- Piazza di Spagna
- Spanish Steps
- Villa Borghese
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Greet day 3 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Rome for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Vatican City and Rome.
Enjoy the perfect balance of relaxation and exploration in Rome today. One of the most world-famous attractions included on the itinerary is Vatican Museums.
Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the world-famous Trevi Fountain. After exploring the monument, head to Piazza Di Spagna. This world-famous public square is a highlight in Rome. As your day continues, stop by Spanish Steps, known for its enchanting features. Lastly, don’t forget to check out the impressive Villa Borghese. Enjoy exploring this incredible park at your own pace.
When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Savor the flavors at RomAntica, a top pick for dinner tonight. Alternatively, Coso Ristorante beckons with its unique menu offerings. Also, consider DEROMA - Farine Romane. With its consistent customer satisfaction, it’s an excellent option for dining in Rome tonight.
Continue your evening by exploring the vibrant nightlife scene at Sant' Eustachio Caffè, a prime destination for a thrilling night out. Also, don’t forget to check out Yellowsquare Rome, a bar that offers unique local touches. Likewise, Caffè Portofino provides an excellent alternative for a fun evening.
Head back to your accommodation in Rome and get some rest in preparation for another magical day of your road trip in Italy!
Day 4
- Rome
- Florence
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Drive 276 km, 3 hours 31 min
- Basilica of Santa Croce in Florence
- Uffizi Gallery
- Ponte Vecchio
- Piazza della Repubblica
- Cathedral of Santa Maria del Fiore
- piazza della Signoria
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Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Florence. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Florence. You will spend 1 night here for some well-deserved relaxation.
Prepare for a day full of fun adventures, picturesque spots, and historic treasures. When you’re ready, kick off your sightseeing adventure at Basilica Of Santa Croce In Florence. This interesting church is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Uffizi Gallery, one of the city’s best highlights.
Next, check out Ponte Vecchio, one of the most wondrous places to see in Rome. This historical landmark is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Piazza Della Repubblica. Wander around and soak in the romantic atmosphere this public square offers. Then, head to Cathedral Of Santa Maria Del Fiore, a top-rated church that adds another dimension to your day. Finally, visit the top-rated Piazza Della Signoria, the last of our attraction recommendations for today.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.
Enjoy a lovely dining experience at Ristorante Oliviero 1962, a popular restaurant in Florence. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Florence at Di Poneta Novoli, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Caffe San Firenze. It’s yet another ideal choice to enhance your time in Florence tonight.
Continue the enjoyment post-dinner at Manifattura, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Se·sto On Arno Rooftop Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Il Vinile. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.
Raise your glass to another unforgettable day in Italy!
Day 5
- Florence
- Pescara
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Drive 425 km, 5 hours 36 min
- Fortezza Medicea
- Basilica of San Domenico
- Siena Cathedral
- piazza del Campo
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On day 5 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Siena. When you’re not sightseeing, take time to relax at your selected hotel in Pescara, where you’ll be staying for 1 night.
Immerse yourself in Florence’s rich culture with today's sightseeing itinerary. Start your journey at Fortezza Medicea (siena). This standout monument is sure to ignite your curiosity. Next, dive into the stunning features of Basilica Of San Domenico, a must-visit church in the city.
In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Siena Cathedral, a popular church. For a change of scene, check out Piazza Del Campo, known for its visually striking features.
At the end of the day, you will drive to Pescara, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As dinnertime approaches, it's time to head out for a bite to eat in Pescara. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Dine in style at Ciacco, a top recommendation for dinner tonight. Or, for a change of pace, Bar Sara boasts a menu that's sure to impress. Also, be sure to check out Ristorante Franco. Known as a local hotspot, it’s a great choice for tonight in Pescara.
After your delicious meal, get a taste of the vibrant nightlife with a visit to Bar Napoli, known for its inviting atmosphere. Bar Supermarket is another great option if you’re looking for a place to get the night started. Similarly, Post Bar provides a great setting to enjoy the night away.
Head back to your accommodation in Pescara and get some rest in preparation for another magical day of your road trip in Italy!
Day 6
- Pescara - Departure day
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- Nature Reserve Pineta Dannunziana
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Day 6 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Pescara before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, we recommend visiting Nature Reserve Pineta Dannunziana, a stunning nature reserve before you head out.
Maximize your last day in Italy and go on a shopping spree in Pescara’s shopping center, the lively Centro Commerciale Pescara Porta Nuova. Browse for souvenirs to remind you of your wonderful journey in Italy.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Pescara.
You’ll then say farewell to Pescara. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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