5-Day the Czech Republic Self-Drive Road Trip With Itinerary from Prague to Plzeň and surrounding area

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Photo of famous Charles Bridge over the Vltava river in Prague, Czech Republic.
Photo of tourist dressed in the old town square of Prague, Czech Republic.
Photo of aerial view of old town Square in Prague, Czech Republic.
Photo of architecture and landmark of Prague, Czech Republic.
Photo of gulls over Prague chimes and Tynsky cathedral at summer day, Czech Republic.
Photo of scenic view of the old town pier architecture and Charles Bridge over Vltava river in Prague, Czech Republic.
Photo of Prague beautiful panoramic sunny aerial drone view above Prague Old Town, Czech Republic.
Photo of Prague Old Town Square Czech Republic, sunrise city skyline at Astronomical Clock Tower.
Photo of woman enjoys the elevated view over the city of Prague, Czech Republic, on a sunny autumn day.
Photo of Prague street, Czech Republic.
Photo of Prague, Czech Republic. Charles Bridge and Old Town Tower at sunrise.
Aerial landscape of czech town of Pilsen with old historical houses in fall day
St. Bartholomew's Cathedral in the main square of Plzen with a fountain on the foreground against blue sky and clouds sunny day. Czech Republic, Pilsen. Famous landmark in Czech Republic, Bohemia.
Museum and Gallery of the Northern Pilsen Region at Marianska Tynice. Baroque Church of the Annunciation and the Cistercian Provost Office built in the 18th century. Tynec, CZ.
PILSEN, CZECH REPUBLIC -Pilsner Urquell Brewery main gate at sunset.
The Great Synagogue in Plzen, the largest synagogue in the Czech Republic.
Josef Kajetán Tyl Theatre (Czech: Divadlo Josefa Kajetána Tyla) is a main theatre in Plzeň, Czech Republic.
Josef Kajetán Tyl Theatre (Czech: Divadlo Josefa Kajetána Tyla) is a main theatre in Plzeň, Czech Republic.
The Black Tower (old water tower) in Pilsen, Czech Republic
Pilsen, Czech Republic - Pilsner Urquell Brewery from 1839, Pilsen town is known as the birthplace of the Pilsener beer style
Town Hall in Renaissance style in Plzen, Czech Republic
Aerial view of rivers confluence Radbuza and Mze in Pilsen city, Czech republic, European union. Cityscape from above.
Night Shot Reconstructed Wilson's Bridge in Pilsen in The Czech Republic above Radbuza
District Court of Plzeň-City District, Czech Republic
Beautiful cityscape of Pilsen, Czech Republic with dominant Water Tower, Vodarenska vez in Czech, photographed from park by Mlynska Strouha. Plzen city, Bohemia, Czechia. Tourist destination.
Domazlice historical city center and old town square with white tower,church and medieval gates,Chodsko region,Pilsen,Czech republic,night panorama cityscape view
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Experience the freedom of the open road in the Czech Republic as you embark on an unforgettable 5-day road trip! This experience caters to every traveler, featuring destinations like Prague, Plzeň, and Karlštejn.

This perfectly planned road trip itinerary in the Czech Republic takes you through some of the best places to see in the country. You will spend 3 nights in Prague and 1 night in Plzeň. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Prague, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Prague Castle and Charles Bridge are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Old Town Square, learn more about the unique St. Vitus Cathedral, and immerse yourself in the vibrant atmosphere of Prague Astronomical Clock.

As you hit the open road and drive through Prague, Plzeň, and Karlštejn, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Franz Kafka - Rotating Head
VyšehradDancing HouseSt. Vitus CathedralPrague CastleMalá Strana
Old Town SquarePrague Astronomical ClockPrague Zoo
Cathedral of St. BartholomewPlzeň ZooKarlštejn Castle
Charles Bridge

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Day 1

Day 1

  • Prague - Arrival day
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  • Franz Kafka - Rotating Head
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Your road trip adventure in the Czech Republic begins as soon as you reach Prague and pick up your car. You’ll stay in Prague for 2 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Prague is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Franz Kafka - Rotating Head By David Cerny, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Prague. Check-in typically starts around 2 to 4 PM at hotels in the Czech Republic. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at U Tellerů, an iconic dining spot in Prague. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Restaurace U Bansethů, a popular restaurant in Prague. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Eska Restaurant and Bakery, a hidden gem nestled in Prague. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Anonymous Shrink's Office stands out as an excellent choice for a post-dinner cocktail. Alternatively, Bar No. 7 - Prague offers an ideal atmosphere to enjoy the pleasures of the night. Kontakt Bar is also a great option that provides a perfect setting for a relaxing evening.

Raise a toast to the start of your 5-day road trip in the Czech Republic!

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Day 2

Day 2

  • Prague
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Drive 15 km, 46 min

  • Vyšehrad
  • Dancing House
  • St. Vitus Cathedral
  • Prague Castle
  • Malá Strana
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On day 2 of your road trip, you will have an entire day to explore Prague. You’ll stay in Prague for 1 night and discover all the best things to see and do in the area.

Set aside time today to explore Malá Strana, a standout neighborhood that reflects the essence of the city. While you're there, you'll also be within reach of some of the city's top landmarks, making it easy to maximize your day.

Today’s agenda in Prague includes a castle, an art installation, and a church. Vyšehrad is must-visit castle and a great starting point for the day. Next, continue your journey to Dancing House, a spectacular art installation, located just a leisurely stroll away. Next, head to St. Vitus Cathedral, a culturally significant church, also available for your discovery today.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. The Czech Republic is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Prague. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at Brasileiro Restaurant, a top-rated dining spot in Prague. If you're in the mood for something new, try Restaurant Meat Beer, another premier location with a delectable menu. You might also want to book a table at Restaurace Století. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Prague.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Bowla Bar stands out as an excellent choice for a post-dinner cocktail. Alternatively, The Saints offers an ideal atmosphere to enjoy the pleasures of the night. Beergeek Bar is also a great option that provides a perfect setting for a relaxing evening.

Relax and reminisce about your day in the Czech Republic and look forward to more memorable moments to come!

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Day 3

Day 3

  • Prague
  • Plzeň-City District
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Drive 103 km, 1 hour 34 min

  • Old Town Square
  • Prague Astronomical Clock
  • Prague Zoo
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Experience an unparalleled adventure on day 3 of your road trip in the Czech Republic. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Prague. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Plzeň. You will spend 1 night here for some well-deserved relaxation.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Prague allows for both. Start by heading to Old Town Square. This world-famous public square provides an insightful glimpse into the city's identity. Next, discover Prague Astronomical Clock, an UNESCO world heritage-designated historical landmark, promising a delightful encounter.

Continue your sightseeing with a visit to Prague Zoo, a widely recognized zoo.

At the end of the day, you will drive to Plzeň, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Plzeň, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a delicious meal at Raven Pub City, a top-rated dining destination in Plzeň. If you're in the mood to try something new, consider Restaurace & Hotel U Salzmannů, another top spot with a mouthwatering menu. You might also want to secure a reservation at Pláž OSTENDE BOLEVÁK. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Plzeň this evening.

After your meal, keep the night alive at a bar like Francis - Beer Café, known for its lively atmosphere. My Friends Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Beer Bar Pioneer offers an excellent atmosphere for those looking to amp up the evening.

Relax and recharge in preparation for another adventurous day in the Czech Republic!

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Day 4

Day 4

  • Plzeň-City District
  • Prague
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Drive 117 km, 1 hour 58 min

  • Cathedral of St. Bartholomew
  • Plzeň Zoo
  • Karlštejn Castle
  • More

Dive into day 4 of your remarkable road trip in the Czech Republic. Today you will explore Plzeň and Karlštejn, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Prague. You’ll stay here for 1 night.

Get ready for an exciting day in Plzeň. Today’s sightseeing agenda includes a church, a zoo, and a castle. Begin your adventure at Cathedral Of St. Bartholomew. This is a worthwhile church you should not miss. Another must-see is Dinopark Plzeň, a notable zoo in Plzeň.

When you’re ready for the next sight, head to Karlštejn Castle.

When you’re done exploring for the day, you’ll drive to your hotel in Prague. Check in and spend some time relaxing before you head out to tour the city.

Indulge in a memorable dining experience at one of Prague's most popular restaurants, and connect with friendly locals for an authentic adventure.

Don’t miss out on dining at BeBop Bar, a top-rated dining destination in Prague. If you're in the mood to try something new, consider Café restaurant Palanda, another top spot with a mouthwatering menu. You might also want to secure a reservation at Restaurace Tiskárna. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Prague this evening.

If you’re not ready to end the night just yet, Uhříněveský Bar offers a perfect venue to relax and savor a drink. Similarly, Boothill Bar is well-suited for those looking to unwind in a social setting. Manesova Bar And Books is another excellent spot to enjoy a nightcap after a delightful meal.

Savor another day of unforgettable experiences in the Czech Republic!

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Day 5

Day 5

  • Prague - Departure day
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  • Charles Bridge
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Day 5 of your road trip in the Czech Republic is your departure day. This is your chance to catch a last glimpse of Prague before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Charles Bridge. This globally renowned historical landmark is a popular place to see in the city.

Maximize your last day in the Czech Republic and go on a shopping spree in Prague’s shopping center, the lively Wenceslas Square. Browse for souvenirs to remind you of your wonderful journey in the Czech Republic.

Before you conclude your road trip in the Czech Republic, drop by another restaurant for a last chance at a memorable dining experience in Prague.

If you're in the mood to try something new, consider U Fleků, another top spot with a mouthwatering menu.

You’ll then say farewell to Prague. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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