10-Day Greece Self-Drive Road Trip With Itinerary from Ioannina traveling south to Patras, Athens, Chalkida, and Larissa

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Experience the freedom of the open road in Greece as you embark on an unforgettable 10-day road trip! This experience caters to every traveler, featuring destinations like Ioannina, Perama, Neo Bizani, Patras, Antirio, Mesolongi, Kallithea, Athens, Mykines, Chalkida, Thermopyles, Larissa, Trikala, and Kastraki.

This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 2 nights in Ioannina, 1 night in Patras, 4 nights in Athens, 1 night in Chalkida, and 1 night in Larissa. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Ioannina, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. Acropolis Of Athens and Parthenon are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Acropolis Museum, learn more about the unique Stavros Niarchos Foundation Cultural Center, and immerse yourself in the vibrant atmosphere of Meteora.

As you hit the open road and drive through Ioannina, Perama, Neo Bizani, Patras, Antirio, Mesolongi, Kallithea, Athens, Mykines, Chalkida, Thermopyles, Larissa, Trikala, and Kastraki, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Ioannina Castle
The Clock Tower of IoanninaLitharitsia parkIch Kale Acropolis of IoanninaCave of PeramaVrellis Greek History Museum (Wax Museum)
Rion-Antirion BridgeGarden of HeroesWater SquareStavros Niarchos Foundation Cultural CenterStavros Niarchos Park
Archeological Museum of MycenaeMycenaeTreasury of Atreus" or "Tomb of Agamemnon
Temple of Olympian ZeusAcropolis MuseumOdeon of Herodes AtticusAcropolis of AthensParthenon
Philopappos HillMonastiraki SquareAncient Agora of AthensAdrianou StreetMonastiraki

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Day 1

Day 1

  • Ioannina - Arrival day
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  • Ioannina Castle
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Your road trip adventure in Greece begins as soon as you reach Ioannina and pick up your car. You’ll stay in Ioannina for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Ioannina is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ioannina Castle, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Ioannina. Check-in typically starts around 2 to 4 PM at hotels in Greece. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Ioannina, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at To Dodeka Cafe Bar, an iconic dining spot in Ioannina. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Mustagogia, a popular restaurant in Ioannina. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Accademia Del Panino, a hidden gem nestled in Ioannina. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Round off your dining experience by visiting ⚜ V E D E M A ⚜, a prime location for a drink. Alternatively, explore the distinctive characteristics of Hogwarts Tales And Spirits, a bar catering to every mood and preference. Chevalier likewise offers a unique atmosphere, perfect for a memorable night out.

Raise a toast to the start of your 10-day road trip in Greece!

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Day 2

Day 2

  • Ioannina
  • Patras
  • More

Drive 235 km, 3 hours 24 min

  • The Clock Tower of Ioannina
  • Litharitsia park
  • Ich Kale Acropolis of Ioannina
  • Cave of Perama
  • Vrellis Greek History Museum (Wax Museum)
  • More

On day 2 of your road trip in Greece, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Ioannina, Perama, and Neo Bizani. In the evening, you’ll end up in Patras, where you will stay for 1 night.

Today's adventure in Ioannina promises more breathtaking discoveries and enriching experiences! Begin at The Clock Tower Of Ioannina. This culturally significant monument is a highlight of any visit in the city. Then, enjoy Litharitsia Park, another history-steeped attraction that never fails to captivate visitors. Next, head over to Ic Kale Acropolis Of Ioannina, one of the city’s most underrated attractions, known for its respected features.

If you’re looking for more, spend time soaking in the atmosphere of Cave Of Perama. This enchanting cave is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Moyseio Ellinikis Istorias Payloy Vrelli, an intriguing museum, and take a stroll around the area.

At the end of the day, you will drive to Patras, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Patras. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Tag, an iconic dining spot in Patras. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bianco, a popular restaurant in Patras. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Carousello, a hidden gem nestled in Patras. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Keep the evening going at Sofita, a great choice for enjoying the after-dinner hours with a drink. You could also go to Charama Therino, which offers a similarly pleasant setting and great drinks. Another option is Notos, which provides an inviting environment for unwinding after a busy day out.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Greece.

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Day 3

Day 3

  • Patras
  • Athens
  • More

Drive 301 km, 4 hours 1 min

  • Rion-Antirion Bridge
  • Garden of Heroes
  • Water Square
  • Stavros Niarchos Foundation Cultural Center
  • Stavros Niarchos Park
  • More

Embark on another extraordinary experience on day 3 of your road trip in Greece. Today, you will make 3 stops and experience some of the highlights of Antirio, Mesolongi, and Kallithea. At the end of the day, you will enjoy the comforts of a top-rated hotel in Athens, which will be your home away from home for 4 nights.

Start your adventure at Charilaos Trikoupis Rio - Antirrio Bridge. This intriguing monument is a must-visit for travelers looking for a unique holiday experience. Make your way to Garden Of Heroes located in Patras for another exciting encounter.

Next, immerse yourself in the setting of Water Square. After the park, continue your tour of the village with a visit to Stavros Niarchos Foundation Cultural Center. Visitors usually appreciate the stunning features of this cultural center. Next up is Stavros Niarchos Park, a highly recommended park.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Athens. Athens offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Athens, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Prepare for an extraordinary culinary adventure in Athens by booking a table at Hytra, a 1-star Michelin restaurant that boasts an exceptional modern menu. For a different flavor experience, head to Spondi, renowned for its delectable french dishes. This 1-star Michelin restaurant consistently wows guests, making it a memorable stop during your holiday. Looking for another option? Visit The Zillers, a local gem known for its delightful contemporary and greek cuisine in Athens. Nestled in the city's heart, this 1-star Michelin restaurant is a perfect choice for discerning restaurant-goers seeking a new experience.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Mayros Gatos stands out as an excellent choice for a post-dinner cocktail. Alternatively, Kuko's The Bar offers an ideal atmosphere to enjoy the pleasures of the night. Revolt Street Bar is also a great option that provides a perfect setting for a relaxing evening.

Head back to your accommodation in Athens and get some rest in preparation for another magical day of your road trip in Greece!

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Day 4

Day 4

  • Athens
  • More

Drive 237 km, 3 hours 22 min

  • Archeological Museum of Mycenae
  • Mycenae
  • Treasury of Atreus" or "Tomb of Agamemnon
  • More

On day 4 of your road trip, you’ll start and end your day in Athens, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Mykines. You still have 3 nights left in Athens.

Get ready for a day filled with fun adventures, scenic views, and picturesque spots in the charming village of Athens. Your adventure starts at Archeological Museum Of Mycenae, an underrated local hot spot. Another notable attraction to explore is Mycenae. This popular archeological site is known for its respected appeal.

After soaking in the highlights of these sights, take some time to wander Athens's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to "treasury Of Atreus" Or "tomb Of Agamemnon". This symbolic archeological site offers a fascinating experience that many visitors find memorable.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Athens.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Athens. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at Harvest Coffee & Wine, a highly-rated dining destination in Athens. If you're eager to try something different, consider 42 Barstronomy Athens, another top spot with a tantalizing menu. You might also want to secure a reservation at O Babas. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Athens this evening.

After your meal, keep the night alive at a bar like Tiki Bar Athens, known for its lively atmosphere. Brettos is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Luxus Bar Bistro offers an excellent atmosphere for those looking to amp up the evening.

Head back to your accommodation in Athens and get some rest in preparation for another magical day of your road trip in Greece!

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Day 5

Day 5

  • Athens
  • More

Drive 6 km, 45 min

  • Temple of Olympian Zeus
  • Acropolis Museum
  • Odeon of Herodes Atticus
  • Acropolis of Athens
  • Parthenon
  • More

On day 5 of your road trip, you will have an entire day to explore Athens. You’ll stay in Athens for 2 nights and discover all the best things to see and do in the area.

Prepare for a day full of family-friendly attractions, scenic views, and photo-friendly spots. When you’re ready, kick off your sightseeing adventure at Temple Of Olympian Zeus. This captivating archeological site is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Acropolis Museum, one of the city’s best highlights.

Next, check out Odeon Of Herodes Atticus, one of the most captivating places to see in Athens. This archeological site is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Acropolis Of Athens. Wander around and soak in the UNESCO world heritage-listed atmosphere this archeological site offers. Then, head to Parthenon, a top-rated archeological site that adds another dimension to your day.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Greece is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Athens, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a lovely dining experience at Cookoovaya, a popular restaurant in Athens. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Athens at Karamanlidika, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Estiatorio Auli. It’s yet another ideal choice to enhance your time in Athens tonight.

After your meal, keep the night alive at a bar like Kazu Cafe-bar, known for its lively atmosphere. Upupa Epops - The Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Gazarte offers an excellent atmosphere for those looking to amp up the evening.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Greece.

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Day 6

Day 6

  • Athens
  • More

Drive 7 km, 46 min

  • Philopappos Hill
  • Monastiraki Square
  • Ancient Agora of Athens
  • Adrianou Street
  • Monastiraki
  • More

Day 6 offers a multitude of experiences. You will stay in Athens for 1 night more, offering you enough time to explore at a relaxed pace.

A visit to Adrianou Street in Athens is a must on the agenda today. This street is full of hidden gems and character, perfect for a leisurely stroll. Plus, you’ll be close to some of the city’s most famous sights. Don’t forget to check out Monastiraki as well, a neighborhood that adds another layer to your exploration.

Bring your curiosity for today’s adventure around Athens. Some of the city’s most loved attractions await! Philopappos Hill is the perfect place to start. This park is one of the most popular places to visit in Athens. Next, head to Monastiraki Square 6, a captivating public square, known for its instagrammable features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Ancient Agora Of Athens. This breathtaking archeological site is a highly recommended experience. Visit these for an interesting touch to your journey.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Greece is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Athens's best restaurants.

Have a fantastic dining experience at Beer Tales, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Oinomageireio Epirus (est.1898) offers an enticing alternative with its varied menu. Additionally, To Kafeneio is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Athens.

To truly maximize your evening out, consider visiting Ipitou The Bar after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Lot 51, another bar with an inviting ambiance. Similarly, Klōstḗrion also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Get a good night's sleep and look forward to another great day on the road in Greece!

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Day 7

Day 7

  • Athens
  • Chalkida
  • More

Drive 87 km, 1 hour 35 min

  • National Archaeological Museum of Athens
  • Athens National Garden
  • Technopolis City of Athens
  • More

On day 7 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 1 destination, Athens. When you’re not sightseeing, take time to relax at your selected hotel in Chalkida, where you’ll be staying for 1 night.

Bring your curiosity for today’s adventure around Athens. Some of the city’s most loved attractions await! National Archaeological Museum Of Athens is the perfect place to start. This museum is one of the most popular places to visit in Athens. Next, head to National Garden Of Athens, a popular botanical garden, known for its serene features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Technopolis City Of Athens. This photogenic cultural center is a highly recommended experience. Visit these for an interesting touch to your journey.

When you’re done exploring for the day, you’ll drive to your hotel in Chalkida. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Chalkida. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a wonderful meal at Stavento, a top-rated dining spot in Chalkida. If you're in the mood for something new, try 25 DRAMIA, another premier location with a delectable menu. You might also want to book a table at Psistaria Apostoloy. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Chalkida.

Following your dinner, dive into the local bar culture at Boheme Cafe Bar. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Galatiko Chorio, the perfect place for those looking to experience the best of the nightlife. Similarly, Euan provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Relax and recharge in preparation for another adventurous day in Greece!

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Day 8

Day 8

  • Chalkida
  • Larissa
  • More

Drive 301 km, 3 hours 34 min

  • Waterfront of Chalkida
  • Karababa Castle
  • Memorial of Leonidas and 300 Spartans
  • More

Dive into day 8 of your remarkable road trip in Greece. Today you will explore Chalkida and Thermopyles, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Larissa. You’ll stay here for 1 night.

Brace yourself for today’s incredible lineup of attractions in Chalkida, featuring fun adventures, romantic experiences, and scenic views. Start at Chalkida's Seaside, a curiosity-inducing boardwalk in the city. Then, head to Karababa Castle and soak in the ambiance of this history-steeped castle.

There are many interesting places to see in Chalkida, and when you are ready for more, go to Memorial To Leonidas And 300 Spartans. This is one of the city’s most frequently visited picture-perfect spots of interest.

At the end of the day, you will drive to Larissa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Larissa's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a lovely dining experience at Nonna Rossa, a popular restaurant in Larissa. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Larissa at Vosporos | Restaurant • Bar, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated THE ALLEY. It’s yet another ideal choice to enhance your time in Larissa tonight.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Sherlock Easy Bar, a well-loved spot among locals and tourists. Or, head to Kiou. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Wisedog, another top-rated place in the area.

Take some time to reflect on your day and savor another beautiful night in Greece.

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Day 9

Day 9

  • Larissa
  • Ioannina
  • More

Drive 199 km, 4 hours 20 min

  • Trikala City Center Square
  • Matsopoulos Park
  • Meteora
  • Monastery of Varlaam
  • More

Experience an unparalleled adventure on day 9 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Trikala and Kastraki. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Ioannina. You will spend 1 night here for some well-deserved relaxation.

Discover a day packed with family-friendly attractions, romantic experiences, and breathtaking views in Larissa. Begin your sightseeing with Trikala City Center Square. This worthwhile public square is one of the top attractions in the city. Proceed to Matsopoulos Park, another must-visit attraction.

As you wander through the inviting streets of Larissa, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Meteora. This locally renowned monastery is a traveler-favorite. Not far away, you’ll find Monastery Of Varlaam, another key site on your sightseeing itinerary.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Ioannina. Ioannina offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Ioannina. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a lovely meal at Spitaki me thea, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Frontzoy Politeia - Frontzu Politia Restaurant is another top choice with a popular menu. You could also check for a table at Papi Cafe Bistro. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Ioannina tonight.

Continue your evening by exploring the vibrant nightlife scene at Scala, a prime destination for a thrilling night out. Also, don’t forget to check out Route 66 Bar, a bar that offers unique local touches. Likewise, Palia Agora provides an excellent alternative for a fun evening.

Celebrate another amazing day of your road trip adventure in Greece!

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Day 10

Day 10

  • Ioannina - Departure day
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  • Kaloutsiani Mosque
  • More

Day 10 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Ioannina before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Kaloutsiani Mosque. This worthwhile mosque is a popular place to see in the city.

On your last day in Greece, take time to indulge in shopping at Ioannina’s popular marketplace, Epirus Street. Look for keepsakes or souvenirs to remind you of your trip. Browse boutiques to find unique and stylish fashion pieces. Wrap up your shopping with a drink and some pastries at a cozy cafe.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Ioannina.

Have a fantastic dining experience at PRESVEIA Restaurant Meze, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Frontzu Politia - Hotel offers an enticing alternative with its varied menu.

You’ll then say farewell to Ioannina. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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