4-Day Greece Self-Drive Road Trip With Itinerary from Ioannina to Thessaloniki

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Photo of Ioannina lake Pamvotida in Epirus Region, Greece.
Photo of Ioannina city and the lake Pamvotis located in Epirus, Greece.
Photo of Loannina lake in autumn season with platanus trees reflecter in the water, in greece
Photo of aerial view of Ioannina city in Greece.
Photo of the lake Pamvotis. Ioannina city, Greece.
Photo of Ioannina city old tranditional pedestrian street called Soutsou in greece.
Photo of autumn colors in Ioannina city ,Epirus, Greece.
Photo of famous ruins of Ali Pasha's palace and the Tower of Bohemond in the old byzantine castle of Ioannina, Greece.
Photo of aerial view of Ioannina city in Greece.
Photo of panoramic aerial view of the town and the Pamvotis lake, Ioannina in Greece.
Fethiye Mosque with the Tomb of Ali Pasha in the foreground, Ioannina, Greece
EPIRUS, GREECE. Politsa (or "Politsas") bridge over Arachthos river, Katsanochoria region, North Tzoumerka municipality, Ioannina prefecture.
Photo of bird's eye view to the promenade of Thessaloniki.
Photo of Saint Paul cathedral in Thessaloniki, Greece.
Photo of the White Tower in Thessaloniki, Greece.
Photo of Aristotelous Square at Thessaloniki city, Panoramic view.
Photo of Aristotelous square, the heart of Thessaloniki city, Greece.
Photo of beautiful Rotonda in Thessaloniki on a hot sunny summer day.
Photo of Agia Anna monastery guesthouses in Mount Athos, Thessaloniki.
Photo of aerial view of Thessaloniki alongisde an old fortification, Greece.
Photo of a narrow street in the old town of Thessaloniki, Greece.
Photo of aerial panoramic view of the main symbol of Thessaloniki city.
Photo of Byzantine fortress situated on the north-eastern corner of the acropolis of Thessaloniki in Greece.
Photo of tourist enjoys the view of Galerius Arch in Thessaloniki city in Greece.
Archaeoiogical Museum of Thessaloniki,Thessaloniki.
Aristotelous Square,Thessaloniki
View of the pier of Neoi Epivates suburb of Thessaloniki, Greece.
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Experience the freedom of the open road in Greece as you embark on an unforgettable 4-day road trip! This experience caters to every traveler, featuring destinations like Ioannina, Perama, Thessaloniki, Kastraki, and Kalambaka.

This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 2 nights in Ioannina and 1 night in Thessaloniki. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Ioannina, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Arch Of Galerius And Rotunda, learn more about the unique Ioannina Castle, and immerse yourself in the vibrant atmosphere of Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour.

As you hit the open road and drive through Ioannina, Perama, Thessaloniki, Kastraki, and Kalambaka, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Ioannina Castle
Cave of PeramaWhite Tower of ThessalonikiArch of GaleriusAristotelous Square
The Great Meteoron Holy Monastery of the Transfiguration of the SaviourMonastery of VarlaamMain Observation Deck of MeteoraNatural History Museum of Meteora and Mushroom Museum
Ich Kale Acropolis of Ioannina

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Day 1

Day 1

  • Ioannina - Arrival day
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  • Ioannina Castle
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Welcome to Ioannina, the perfect starting point for your road trip in Greece! Pick up your rental car and let the adventure begin. You will spend 1 night immersing yourself in Ioannina's charm before embarking on the next leg of your journey.

Ioannina is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ioannina Castle, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Ioannina. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Ioannina, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at To Dodeka Cafe Bar, an iconic dining spot in Ioannina. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Mustagogia, a popular restaurant in Ioannina. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Accademia Del Panino, a hidden gem nestled in Ioannina. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at ⚜ V E D E M A ⚜, a well-loved spot among locals and tourists. Or, head to Hogwarts Tales And Spirits. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Chevalier, another top-rated place in the area.

Raise a toast to the start of your 4-day road trip in Greece!

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Day 2

Day 2

  • Ioannina
  • Thessaloniki
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Drive 263 km, 3 hours 41 min

  • Cave of Perama
  • White Tower of Thessaloniki
  • Arch of Galerius
  • Aristotelous Square
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Embark on another extraordinary experience on day 2 of your road trip in Greece. Today, you will make 2 stops and experience some of the highlights of Perama and Thessaloniki. At the end of the day, you will enjoy the comforts of a top-rated hotel in Thessaloniki, which will be your home away from home for 1 night.

Today's adventure in Ioannina promises more breathtaking discoveries and enriching experiences! Begin at Cave Of Perama. This picturesque cave is a highlight of any visit in the town. Then, enjoy White Tower Of Thessaloniki, another culturally significant attraction that never fails to captivate visitors. Next, head over to Arch Of Galerius And Rotunda, one of the town’s most captivating attractions, known for its instagrammable features.

If you’re looking for more, spend time soaking in the atmosphere of Aristotelous Square. This romantic public square is frequented by locals and tourists alike. To complete your memorable day, make sure to take a stroll around the area.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Thessaloniki. Thessaloniki offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Thessaloniki's best restaurants.

Dine in style at Kitchen Bar, a top recommendation for dinner tonight. Or, for a change of pace, The Greek boasts a menu that's sure to impress. Also, be sure to check out Phanós. Known as a local hotspot, it’s a great choice for tonight in Thessaloniki.

Round off your dining experience by visiting Beetle Bar, a prime location for a drink. Alternatively, explore the distinctive characteristics of Vogatsikou 3, a bar catering to every mood and preference. Souel likewise offers a unique atmosphere, perfect for a memorable night out.

Savor another day of unforgettable experiences in Greece!

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Day 3

Day 3

  • Thessaloniki
  • Ioannina
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Drive 345 km, 5 hours 4 min

  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Monastery of Varlaam
  • Main Observation Deck of Meteora
  • Natural History Museum of Meteora and Mushroom Museum
  • More

On day 3 of your road trip in Greece, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Kastraki and Kalambaka. In the evening, you’ll end up in Ioannina, where you will stay for 1 night.

Today’s agenda in Thessaloniki includes a monastery, an observation deck, and a museum. Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour is must-visit monastery and a great starting point for the day. Next, continue your journey to Monastery Of Varlaam, a locally appreciated monastery, located just a leisurely stroll away. Next, head to Main Observation Deck Of Meteora, an eye-catching observation deck, also available for your discovery today.

When you’re done exploring for the day, you’ll drive to your hotel in Ioannina. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Ioannina. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Spitaki me thea, a highly-rated dining destination in Ioannina. If you're eager to try something different, consider Frontzoy Politeia - Frontzu Politia Restaurant, another top spot with a tantalizing menu. You might also want to secure a reservation at Papi Cafe Bistro. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Ioannina this evening.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Scala stands out as an excellent choice for a post-dinner cocktail. Alternatively, Route 66 Bar offers an ideal atmosphere to enjoy the pleasures of the night. Palia Agora is also a great option that provides a perfect setting for a relaxing evening.

Relax and reminisce about your day in Greece and look forward to more memorable moments to come!

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Day 4

Day 4

  • Ioannina - Departure day
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  • Ich Kale Acropolis of Ioannina
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Day 4 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Ioannina before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Ic Kale Acropolis Of Ioannina. This beloved archeological site is a popular place to see in the city.

On your last day in Greece, take time to indulge in shopping at Ioannina’s popular marketplace, Epirus Street. Look for keepsakes or souvenirs to remind you of your trip. Browse boutiques to find unique and stylish fashion pieces. Wrap up your shopping with a drink and some pastries at a cozy cafe.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Ioannina.

Treat yourself to a delicious dinner at PRESVEIA Restaurant Meze, an excellent option for tonight's dining. Looking for something different? Frontzu Politia - Hotel offers a tantalizing alternative with its diverse menu. And don’t miss Equus.

You’ll then say farewell to Ioannina. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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