7-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki to Kalambaka, Ioannina, and Metsovo

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Escape the ordinary with this exciting 7-day road trip through Greece. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 3 nights in Thessaloniki, 1 night in Kalambaka, 1 night in Ioannina, and 1 night in Metsovo. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable The Umbrellas Sculpture By Zogolopoulos, learn more about the unique Arch Of Galerius And Rotunda, and immerse yourself in the vibrant atmosphere of Ioannina Castle.

As you hit the open road and drive through Thessaloniki, Kastraki, Kalambaka, Perama, Ioannina, Anilio, Metsovo, and Vergina, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Ladadika
The Umbrellas by ZongolopoulosMuseum of Byzantine CivilizationArchaeological Museum of ThessalonikiWhite Tower of ThessalonikiAristotelous SquareTsimiski Street
The Great Meteoron Holy Monastery of the Transfiguration of the SaviourMonastery of VarlaamMain Observation Deck of MeteoraNatural History Museum of Meteora and Mushroom MuseumGreek Education Museum
Cave of PeramaSilversmithing MuseumIch Kale Acropolis of IoanninaIoannina CastleLitharitsia parkThe Clock Tower of Ioannina
Καταρράκτης ΑνήλιουΑβερώφειος ΚήποςMetsovo Folk Art Museum (Tossizza Mansion)Metsovo squareAveroff Art Gallery
Polycentric Museum of Aigai (Aegae) - Main BuildingMuseum of the Royal Tombs at Aigai (Aegae)Haliacmon Dam - Artificial Lake at Saint Barbara of Veria
Arch of Galerius

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Day 1

Day 1

  • Thessaloniki - Arrival day
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  • Ladadika
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Your road trip adventure in Greece begins as soon as you reach Thessaloniki and pick up your car. You’ll stay in Thessaloniki for 2 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Thessaloniki is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ladadika, a must-see neighborhood, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Thessaloniki. Check-in typically starts around 2 to 4 PM at hotels in Greece. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Dine in style at Kitchen Bar, a top recommendation for dinner tonight. Or, for a change of pace, The Greek boasts a menu that's sure to impress. Also, be sure to check out Phanós. Known as a local hotspot, it’s a great choice for tonight in Thessaloniki.

Keep the evening going at Beetle Bar, a great choice for enjoying the after-dinner hours with a drink. You could also go to Vogatsikou 3, which offers a similarly pleasant setting and great drinks. Another option is Souel, which provides an inviting environment for unwinding after a busy day out.

Raise a toast to the start of your 7-day road trip in Greece!

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Day 2

Day 2

  • Thessaloniki
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Drive 6 km, 59 min

  • The Umbrellas by Zongolopoulos
  • Museum of Byzantine Civilization
  • Archaeological Museum of Thessaloniki
  • White Tower of Thessaloniki
  • Aristotelous Square
  • Tsimiski Street
  • More

Day 2 of your road trip will take you to the best attractions Thessaloniki has to offer. Cherish the 1 night you have left in Thessaloniki by discovering the best things there are to see and do in the city.

At the top of the list of things to do today is to explore Tsimiski Street, a street that captures the true essence of Thessaloniki. Take your time to uncover its best sides and enjoy its proximity to many of the area’s best attractions.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Thessaloniki allows for both. Start by heading to The Umbrellas Sculpture By Zogolopoulos. This popular art installation provides an insightful glimpse into the city's identity. Next, discover Museum Of Byzantine Culture, a history-steeped museum, promising a delightful encounter.

Continue your sightseeing with a visit to Archaeological Museum Of Thessaloniki, a locally appreciated museum. When you’re done, don’t forget to make a stop at the spectacular White Tower Of Thessaloniki. Round off your day at Aristotelous Square, another gem in Thessaloniki with standout features to discover.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Greece is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Thessaloniki. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely dining experience at Mamalouka, a popular restaurant in Thessaloniki. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Thessaloniki at Clochard, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Sofi's House Restaurant. It’s yet another ideal choice to enhance your time in Thessaloniki tonight.

Explore the vibrant nightlife at Castra- All Day Terrace Bar after your meal, a hub for lively evenings and memorable moments. Or, head to Barbaben - Bar/ba/ben for a great selection of flavorful drinks and a charming setting. Furthermore, Apallou is perfect for those looking to extend their night with a touch of local flavor.

Get a good night's sleep and look forward to another great day on the road in Greece!

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Day 3

Day 3

  • Thessaloniki
  • Meteora
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Drive 240 km, 3 hours 33 min

  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Monastery of Varlaam
  • Main Observation Deck of Meteora
  • Natural History Museum of Meteora and Mushroom Museum
  • Greek Education Museum
  • More

Embark on another extraordinary experience on day 3 of your road trip in Greece. Today, you will make 2 stops and experience some of the highlights of Kastraki and Kalambaka. At the end of the day, you will enjoy the comforts of a top-rated hotel in Kalambaka, which will be your home away from home for 1 night.

Today, you'll explore some of the most beautiful places in Thessaloniki, including a monastery, an observation deck, and a museum. Start your day with a visit to Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour. This underrated monastery is a must-visit in the village. When you’re ready for your next discovery, continue to Monastery Of Varlaam, which may be one of the most UNESCO world heritage-designated places you will experience today.

One of the best things about exploring Thessaloniki on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Main Observation Deck Of Meteora, a curiosity-inducing observation deck in the village. If you’re up for more discoveries, don’t forget to reserve some time for Natural History Museum Of Meteora And Mushroom Museum and Greek Education Museum.

When you’re done exploring for the day, you’ll drive to your hotel in Kalambaka. Check in and spend some time relaxing before you head out to tour the town.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Kalambaka. Enjoy a satisfying meal that will recharge you for tonight's adventures.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Greece.

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Day 4

Day 4

  • Meteora
  • Ioannina
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Drive 107 km, 2 hours 26 min

  • Cave of Perama
  • Silversmithing Museum
  • Ich Kale Acropolis of Ioannina
  • Ioannina Castle
  • Litharitsia park
  • The Clock Tower of Ioannina
  • More

On day 4 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 2 destinations, Perama and Ioannina. When you’re not sightseeing, take time to relax at your selected hotel in Ioannina, where you’ll be staying for 1 night.

Immerse yourself in Kalambaka’s rich culture with today's sightseeing itinerary. Start your journey at Cave Of Perama. This picturesque cave is sure to ignite your curiosity. Next, dive into the eye-catching features of Silversmithing Museum Of Ioannina, a must-visit museum in the town.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Ic Kale Acropolis Of Ioannina, an often recommended archeological site. For a change of scene, check out Ioannina Castle, known for its awe-inspiring features. We also recommend visiting Litharitsia Park. This park is a must for anyone looking to experience the town to the fullest. Lastly, end your day with a visit to The Clock Tower Of Ioannina, yet another intriguing attraction in Kalambaka.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Ioannina. Ioannina offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Ioannina's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a delightful dinner at To Dodeka Cafe Bar, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Mustagogia? It's another excellent option with a diverse menu. Consider reserving a table at Accademia Del Panino as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Ioannina.

Keep the excitement of the evening going by visiting a bar or two. ⚜ V E D E M A ⚜ is an excellent place to start. You could also check out Hogwarts Tales And Spirits, offering a different kind of charm. A last recommendation for the day is Chevalier. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Take some time to reflect on your day and savor another beautiful night in Greece.

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Day 5

Day 5

  • Ioannina
  • Metsovo
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Drive 56 km, 1 hour 15 min

  • Καταρράκτης Ανήλιου
  • Αβερώφειος Κήπος
  • Metsovo Folk Art Museum (Tossizza Mansion)
  • Metsovo square
  • Averoff Art Gallery
  • More

Experience an unparalleled adventure on day 5 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Anilio and Metsovo. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Metsovo. You will spend 1 night here for some well-deserved relaxation.

Discover a day packed with family-friendly attractions, romantic experiences, and natural wonders in Ioannina. Begin your sightseeing with Katarraktis Anilioy. This curiosity-inducing waterfall is one of the top attractions in the village. Proceed to Averofeios Kipos, another must-visit attraction.

As you wander through the inviting streets of Ioannina, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Metsovo Folk Art Museum (tossizza Mansion). This beloved museum is a traveler-favorite. Not far away, you’ll find Metsovo Square, another key site on your sightseeing itinerary. Averoff Art Gallery is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.

At the end of the day, you will drive to Metsovo, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Metsovo's best restaurants.

Savor the flavors at Ta 5 FFFFF, a top pick for dinner tonight. Alternatively, Cafe Petrino beckons with its unique menu offerings. Also, consider Fame Metsovo. With its consistent customer satisfaction, it’s an excellent option for dining in Metsovo tonight.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Karma, a well-loved spot among locals and tourists. Or, head to Krini Cafe Metsovo. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Stul Cafe, another top-rated place in the area.

Get a good night's sleep and look forward to another great day on the road in Greece!

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Day 6

Day 6

  • Metsovo
  • Thessaloniki
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Drive 236 km, 2 hours 41 min

  • Polycentric Museum of Aigai (Aegae) - Main Building
  • Museum of the Royal Tombs at Aigai (Aegae)
  • Haliacmon Dam - Artificial Lake at Saint Barbara of Veria
  • More

Dive into day 6 of your remarkable road trip in Greece. Today you will explore Vergina, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Thessaloniki. You’ll stay here for 1 night.

Today’s well-planned self-sightseeing route offers several family-friendly attractions, picturesque spots, and historic treasures. Whether you decide to explore Metsovo on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Polycentric Museum Of Aigai (aegae) - Main Building is the first of them. Spend some time admiring this history-steeped museum before continuing your journey. Museum Of The Royal Tombs At Aigai (aegae) is your next stop. This frequently visited museum is one of the best-rated sights in Metsovo.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Haliacmon Dam - Artificial Lake At Saint Barbara Of Veria. This romantic lake is a sight to behold.

When you’re done exploring for the day, you’ll drive to your hotel in Thessaloniki. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Thessaloniki. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at Enoches Bar, a top-rated dining spot in Thessaloniki. If you're in the mood for something new, try O Loytros, another premier location with a delectable menu. You might also want to book a table at rOOTS. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Thessaloniki.

Extend your evening after a delightful meal by visiting Peiratis Cafe-bar, which offers the perfect atmosphere for a night out. Moreover, In Rock Cafe Bar is another popular option for a drink or two. Likewise, Tribeca also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Relax and reminisce about your day in Greece and look forward to more memorable moments to come!

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Day 7

Day 7

  • Thessaloniki - Departure day
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  • Arch of Galerius
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Day 7 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Arch Of Galerius And Rotunda, a heritage-rich monument before you head out.

As your final day in Greece unfolds, enjoy a last-minute shopping spree in Thessaloniki's best shopping area, Modiano Market. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Greece.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

If you're eager to try something different, consider Agora Ouzeri, another top spot with a tantalizing menu.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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