7-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki to Kalambaka, Ioannina, and Metsovo

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Photo of Saint Paul cathedral in Thessaloniki, Greece.
Photo of the White Tower in Thessaloniki, Greece.
Photo of Aristotelous Square at Thessaloniki city, Panoramic view.
Photo of Aristotelous square, the heart of Thessaloniki city, Greece.
Photo of beautiful Rotonda in Thessaloniki on a hot sunny summer day.
Photo of Agia Anna monastery guesthouses in Mount Athos, Thessaloniki.
Photo of aerial view of Thessaloniki alongisde an old fortification, Greece.
Photo of a narrow street in the old town of Thessaloniki, Greece.
Photo of aerial panoramic view of the main symbol of Thessaloniki city.
Photo of Byzantine fortress situated on the north-eastern corner of the acropolis of Thessaloniki in Greece.
Photo of tourist enjoys the view of Galerius Arch in Thessaloniki city in Greece.
Archaeoiogical Museum of Thessaloniki,Thessaloniki.
Aristotelous Square,Thessaloniki
View of the pier of Neoi Epivates suburb of Thessaloniki, Greece.
photo of panoramic aerial view of the city of Kalabaka near the famous monasteries on the tops of stone pillars in Meteora. The concept of tourist accommodation and real estate in Greece.
photo of beautiful landscape of monasteries and rocks of Meteora , Greece.
photo of The Great Monastery of Varlaam on the high rock in Meteora, Meteora monasteries, Greece Kalambaka. UNESCO World Heritage.
photo of sunset over monastery of Rousanou and Monastery of St. Nicholas Anapavsa in famous greek tourist destination Meteora in Greece on sunset with sun rays and lens flare.
photo of Holy Monastery of Saint Nicholas Anapafsas at Meteora, Trikala region, Greece, UNESCO World Heritage Site.
photo of Kalabaka or Kalambaka and Kalampaka city center. It is a town and municipality in the Trikala region in Greece.
photo of a church with a tall elegant bell tower on a hill in front of huge rocky mountains above a town, Kalambaka, Meteora, Greece.
photo of sunny summer day among the rocks of Kalambaka. Vineyard belonging to the rock monasteries of Meteora, Greece.
photo of The Assumption of Virgin Mary byzantine church of the 11th century, Kalambaka, Greece.
photo of City Kastraki (Kalambaka) with rocky mountains of Meteora, the landmark of six monasteries in Thessaly, Greece.
photo of The monastery Meteora, rocky monasteries complex in Greece near Kalabaka city. Holy Monastery of the Great Meteoron.
photo of Holy Trinity Monastery (Agia Trias) and Kalabaka town at night in Greece.
photo of Panoramic view of the Assumption of Virgin Mary byzantine church in Meteora, Kalambaka town in Greece, on a sunny summer day.
Photo of Plakidas Bridge in Ioannina in Greece by DanaTentis
Photo of Ioannina lake Pamvotida in Epirus Region, Greece.
Photo of Ioannina city and the lake Pamvotis located in Epirus, Greece.
Photo of Loannina lake in autumn season with platanus trees reflecter in the water, in greece
Photo of aerial view of Ioannina city in Greece.
Photo of the lake Pamvotis. Ioannina city, Greece.
Photo of Ioannina city old tranditional pedestrian street called Soutsou in greece.
Photo of autumn colors in Ioannina city ,Epirus, Greece.
Photo of famous ruins of Ali Pasha's palace and the Tower of Bohemond in the old byzantine castle of Ioannina, Greece.
Photo of aerial view of Ioannina city in Greece.
Photo of panoramic aerial view of the town and the Pamvotis lake, Ioannina in Greece.
Fethiye Mosque with the Tomb of Ali Pasha in the foreground, Ioannina, Greece
EPIRUS, GREECE. Politsa (or "Politsas") bridge over Arachthos river, Katsanochoria region, North Tzoumerka municipality, Ioannina prefecture.
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Explore the best of Greece on a 7-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Thessaloniki, Kastraki, Kalambaka, Perama, Ioannina, Anilio, Metsovo, and Vergina. This road trip itinerary in Greece seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 3 nights in Thessaloniki, 1 night in Kalambaka, 1 night in Ioannina, and 1 night in Metsovo. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable The Umbrellas Sculpture By Zogolopoulos, learn more about the unique Arch Of Galerius And Rotunda, and immerse yourself in the vibrant atmosphere of Ioannina Castle.

As you hit the open road and drive through Thessaloniki, Kastraki, Kalambaka, Perama, Ioannina, Anilio, Metsovo, and Vergina, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Ladadika
The Umbrellas by ZongolopoulosMuseum of Byzantine CivilizationArchaeological Museum of ThessalonikiWhite Tower of ThessalonikiAristotelous SquareTsimiski Street
The Great Meteoron Holy Monastery of the Transfiguration of the SaviourMonastery of VarlaamMain Observation Deck of MeteoraNatural History Museum of Meteora and Mushroom MuseumGreek Education Museum
Cave of PeramaSilversmithing MuseumIch Kale Acropolis of IoanninaIoannina CastleLitharitsia parkThe Clock Tower of Ioannina
Καταρράκτης ΑνήλιουΑβερώφειος ΚήποςMetsovo Folk Art Museum (Tossizza Mansion)Metsovo squareAveroff Art Gallery
Polycentric Museum of Aigai (Aegae) - Main BuildingMuseum of the Royal Tombs at Aigai (Aegae)Haliacmon Dam - Artificial Lake at Saint Barbara of Veria
Arch of Galerius

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Day 1

Day 1

  • Thessaloniki - Arrival day
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  • Ladadika
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Your road trip adventure in Greece begins as soon as you reach Thessaloniki and pick up your car. You’ll stay in Thessaloniki for 2 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Thessaloniki is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ladadika, a must-see neighborhood, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Thessaloniki. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at Kitchen Bar, a popular restaurant in Thessaloniki. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Thessaloniki at The Greek, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Phanós. It’s yet another ideal choice to enhance your time in Thessaloniki tonight.

Unwind after your meal by stepping into Beetle Bar. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Vogatsikou 3 offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Souel, another top-rated bar in the area.

Raise a toast to the start of your 7-day road trip in Greece!

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Day 2

Day 2

  • Thessaloniki
  • More

Drive 6 km, 59 min

  • The Umbrellas by Zongolopoulos
  • Museum of Byzantine Civilization
  • Archaeological Museum of Thessaloniki
  • White Tower of Thessaloniki
  • Aristotelous Square
  • Tsimiski Street
  • More

On day 2 of your road trip, you will have an entire day to explore Thessaloniki. You’ll stay in Thessaloniki for 1 night and discover all the best things to see and do in the area.

Tsimiski Street is one of the highlights of today. Take your time exploring this iconic street in Thessaloniki, which offers a perfect blend of history and culture. Plus, it's close to many must-see landmarks in the city.

Thessaloniki is brimming with adventures. Today’s wonderful stops include an art installation, a museum, a monument, a public square and much more! Begin your sightseeing adventure at the locally renowned The Umbrellas Sculpture By Zogolopoulos and allow yourself time to explore. Just a short distance away you'll find your next stop, Museum Of Byzantine Culture, a heritage-rich museum that draws visitors from far and near.

Continue your journey to Archaeological Museum Of Thessaloniki, one of the city’s most underrated spots that you shouldn’t miss. Another great site to visit is the spectacular White Tower Of Thessaloniki. When you're finished at the monument, Aristotelous Square awaits your visit. This public square is a romantic highlight on today's itinerary.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Greece is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Experience shopping bliss at Thessaloniki as you explore Tsimiski Street. Take a leisurely stroll through unique boutiques and shops, where local treasures are waiting to be found. Beyond shopping, Tsimiski Street offers more options, including unique attractions, key services, and vibrant events.

After a day of adventure, treat yourself to an exquisite dinner at one of Thessaloniki's best restaurants.

Enjoy a delicious meal at Mamalouka, a highly-rated dining destination in Thessaloniki. If you're eager to try something different, consider Clochard, another top spot with a tantalizing menu. You might also want to secure a reservation at Sofi's House Restaurant. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Thessaloniki this evening.

After enjoying a fulfilling meal, continue your evening at Castra- All Day Terrace Bar, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Barbaben - Bar/ba/ben offers a welcoming atmosphere for easing into the nightlife. Similarly, Apallou provides an excellent environment for a relaxed and enjoyable evening.

Raise your glass to another unforgettable day in Greece!

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Day 3

Day 3

  • Thessaloniki
  • Meteora
  • More

Drive 240 km, 3 hours 33 min

  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Monastery of Varlaam
  • Main Observation Deck of Meteora
  • Natural History Museum of Meteora and Mushroom Museum
  • Greek Education Museum
  • More

Experience an unparalleled adventure on day 3 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Kastraki and Kalambaka. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Kalambaka. You will spend 1 night here for some well-deserved relaxation.

Get ready to discover some of the most iconic wonders in Thessaloniki, including a monastery, an observation deck, and a museum. Start your day at Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour. This historic monastery is an often recommended place to see in Thessaloniki. Then, wander over to Monastery Of Varlaam. If picture-perfect sites excite you, this monastery will be right up your alley. Nearby, you’ll also find Main Observation Deck Of Meteora. This mesmerizing observation deck is a favorite among visitors.

Thessaloniki offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Natural History Museum Of Meteora And Mushroom Museum is a beloved spot in the village that will captivate you with its unique charm. When you’re done at the museum, don’t forget to check out the instagrammable Greek Education Museum. Take a moment to appreciate the fascinating details of this intriguing museum.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Kalambaka. Kalambaka offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Kalambaka. If you are looking to dine at a popular restaurant in the town, it's often a good idea to reserve a table in advance.

Take some time to reflect on your day and savor another beautiful night in Greece.

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Day 4

Day 4

  • Meteora
  • Ioannina
  • More

Drive 107 km, 2 hours 26 min

  • Cave of Perama
  • Silversmithing Museum
  • Ich Kale Acropolis of Ioannina
  • Ioannina Castle
  • Litharitsia park
  • The Clock Tower of Ioannina
  • More

On day 4 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 2 destinations, Perama and Ioannina. When you’re not sightseeing, take time to relax at your selected hotel in Ioannina, where you’ll be staying for 1 night.

Immerse yourself in Kalambaka’s rich culture with today's sightseeing itinerary. Start your journey at Cave Of Perama. This enchanting cave is sure to ignite your curiosity. Next, dive into the photogenic features of Silversmithing Museum Of Ioannina, a must-visit museum in the town.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Ic Kale Acropolis Of Ioannina, an intriguing archeological site. For a change of scene, check out Ioannina Castle, known for its romantic features. We also recommend visiting Litharitsia Park. This park is a must for anyone looking to experience the town to the fullest. Lastly, end your day with a visit to The Clock Tower Of Ioannina, yet another worthwhile attraction in Kalambaka.

When you’re done exploring for the day, you’ll drive to your hotel in Ioannina. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Ioannina's best restaurants.

Treat yourself to a delightful dinner at To Dodeka Cafe Bar, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Mustagogia? It's another excellent option with a diverse menu. Consider reserving a table at Accademia Del Panino as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Ioannina.

Continue your evening by exploring the vibrant nightlife scene at ⚜ V E D E M A ⚜, a prime destination for a thrilling night out. Also, don’t forget to check out Hogwarts Tales And Spirits, a bar that offers unique local touches. Likewise, Chevalier provides an excellent alternative for a fun evening.

Say good night to Ioannina and look forward to another great day of your road trip in Greece!

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Day 5

Day 5

  • Ioannina
  • Metsovo
  • More

Drive 56 km, 1 hour 15 min

  • Καταρράκτης Ανήλιου
  • Αβερώφειος Κήπος
  • Metsovo Folk Art Museum (Tossizza Mansion)
  • Metsovo square
  • Averoff Art Gallery
  • More

Dive into day 5 of your remarkable road trip in Greece. Today you will explore Anilio and Metsovo, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Metsovo. You’ll stay here for 1 night.

Today’s agenda in Ioannina includes a waterfall, a park, a museum, a public square, an art gallery and much more! Katarraktis Anilioy is must-visit waterfall and a great starting point for the day. Next, continue your journey to Averofeios Kipos, a frequently visited park, located just a leisurely stroll away. Next, head to Metsovo Folk Art Museum (tossizza Mansion), a historic museum, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Ioannina. When you're ready, let your sightseeing route take you to the underrated Metsovo Square. If you’re looking for more, Averoff Art Gallery is also an underrated attraction that is worthwhile a visit.

At the end of the day, you will drive to Metsovo, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Metsovo. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Make sure to reserve a table at Ta 5 FFFFF, an iconic dining spot in Metsovo. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Cafe Petrino, a popular restaurant in Metsovo. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Fame Metsovo, a hidden gem nestled in Metsovo. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Keep the excitement of the evening going by visiting a bar or two. Karma is an excellent place to start. You could also check out Krini Cafe Metsovo, offering a different kind of charm. A last recommendation for the day is Stul Cafe. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Celebrate another amazing day of your road trip adventure in Greece!

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Day 6

Day 6

  • Metsovo
  • Thessaloniki
  • More

Drive 236 km, 2 hours 41 min

  • Polycentric Museum of Aigai (Aegae) - Main Building
  • Museum of the Royal Tombs at Aigai (Aegae)
  • Haliacmon Dam - Artificial Lake at Saint Barbara of Veria
  • More

On day 6 of your road trip in Greece, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Vergina. In the evening, you’ll end up in Thessaloniki, where you will stay for 1 night.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Metsovo allows for both. Start by heading to Polycentric Museum Of Aigai (aegae) - Main Building. This underrated museum provides an insightful glimpse into the village's identity. Next, discover Museum Of The Royal Tombs At Aigai (aegae), a heritage-rich museum, promising a delightful encounter.

Continue your sightseeing with a visit to Haliacmon Dam - Artificial Lake At Saint Barbara Of Veria, a worthwhile lake.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Thessaloniki. Thessaloniki offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Thessaloniki, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a wonderful meal at Enoches Bar, a top-rated dining spot in Thessaloniki. If you're in the mood for something new, try O Loytros, another premier location with a delectable menu. You might also want to book a table at rOOTS. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Thessaloniki.

After enjoying a fulfilling meal, continue your evening at Peiratis Cafe-bar, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, In Rock Cafe Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Tribeca provides an excellent environment for a relaxed and enjoyable evening.

Raise your glass and celebrate another amazing day of your road trip in Greece!

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Day 7

Day 7

  • Thessaloniki - Departure day
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  • Arch of Galerius
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Day 7 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Arch Of Galerius And Rotunda, a standout monument before you head out.

Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones. Discover boutiques offering an array of stylish fashion choices.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

Savor the flavors at Millet, a top pick for dinner tonight. Alternatively, Agora Ouzeri beckons with its unique menu offerings.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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