6-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki to Kalambaka and Ioannina

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Experience the freedom of the open road in Greece as you embark on an unforgettable 6-day road trip! This experience caters to every traveler, featuring destinations like Thessaloniki, Kastraki, Kalambaka, Ioannina, Anilio, and Metsovo.

This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 3 nights in Thessaloniki, 1 night in Kalambaka, and 1 night in Ioannina. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable The Umbrellas Sculpture By Zogolopoulos, learn more about the unique Arch Of Galerius And Rotunda, and immerse yourself in the vibrant atmosphere of Ioannina Castle.

As you hit the open road and drive through Thessaloniki, Kastraki, Kalambaka, Ioannina, Anilio, and Metsovo, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Ladadika
The Umbrellas by ZongolopoulosArchaeological Museum of ThessalonikiWhite Tower of ThessalonikiAgias Sofias SquareAristotelous SquareTsimiski Street
The Great Meteoron Holy Monastery of the Transfiguration of the SaviourMonastery of VarlaamMain Observation Deck of MeteoraNatural History Museum of Meteora and Mushroom MuseumGreek Education Museum
Silversmithing MuseumIch Kale Acropolis of IoanninaMuseum "Arslan Pasha"Ioannina CastleLitharitsia parkThe Clock Tower of Ioannina
Καταρράκτης ΑνήλιουAveroff Art GalleryMetsovo squareMetsovo Folk Art Museum (Tossizza Mansion)Αβερώφειος Κήπος
Arch of Galerius

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Day 1

Day 1

  • Thessaloniki - Arrival day
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  • Ladadika
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Welcome to Thessaloniki, the perfect starting point for your road trip in Greece! Pick up your rental car and let the adventure begin. You will spend 2 nights immersing yourself in Thessaloniki's charm before embarking on the next leg of your journey.

Thessaloniki is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ladadika, a must-see neighborhood, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Thessaloniki. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at Kitchen Bar, a popular restaurant in Thessaloniki. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Thessaloniki at The Greek, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Phanós. It’s yet another ideal choice to enhance your time in Thessaloniki tonight.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Beetle Bar stands out as an excellent choice for a post-dinner cocktail. Alternatively, Vogatsikou 3 offers an ideal atmosphere to enjoy the pleasures of the night. Souel is also a great option that provides a perfect setting for a relaxing evening.

Raise a toast to the start of your 6-day road trip in Greece!

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Day 2

Day 2

  • Thessaloniki
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Drive 6 km, 1 hour 4 min

  • The Umbrellas by Zongolopoulos
  • Archaeological Museum of Thessaloniki
  • White Tower of Thessaloniki
  • Agias Sofias Square
  • Aristotelous Square
  • Tsimiski Street
  • More

Day 2 of your road trip will take you to the best attractions Thessaloniki has to offer. Cherish the 1 night you have left in Thessaloniki by discovering the best things there are to see and do in the city.

Don’t miss Tsimiski Street in Thessaloniki today, a must-see street that offers a glimpse into the city’s vibrant character. Take your time to explore its best features, and enjoy the convenience of nearby top-rated landmarks.

Thessaloniki is brimming with adventures. Today’s wonderful stops include an art installation, a museum, a monument, a public square and much more! Begin your sightseeing adventure at the interesting The Umbrellas Sculpture By Zogolopoulos and allow yourself time to explore. Just a short distance away you'll find your next stop, Archaeological Museum Of Thessaloniki, a history-steeped museum that draws visitors from far and near.

Continue your journey to White Tower Of Thessaloniki, one of the city’s most extraordinary spots that you shouldn’t miss. Another great site to visit is the captivating Agias Sofias Square. When you're finished at the public square, Aristotelous Square awaits your visit. This public square is an enchanting highlight on today's itinerary.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Greece is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Visit Tsimiski Street in Thessaloniki for an unforgettable shopping experience. Browse unique boutiques and stores, each offering delightful surprises. Find unique souvenirs or items to take home. After shopping, explore what Tsimiski Street has to offer, including attractions, essential services, and vibrant community activities.

As you explore more of Thessaloniki, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a lovely dining experience at Mamalouka, a popular restaurant in Thessaloniki. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Thessaloniki at Clochard, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Sofi's House Restaurant. It’s yet another ideal choice to enhance your time in Thessaloniki tonight.

Continue your evening by exploring the vibrant nightlife scene at Castra- All Day Terrace Bar, a prime destination for a thrilling night out. Also, don’t forget to check out Barbaben - Bar/ba/ben, a bar that offers unique local touches. Likewise, Apallou provides an excellent alternative for a fun evening.

Head back to your accommodation in Thessaloniki and get some rest in preparation for another magical day of your road trip in Greece!

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Day 3

Day 3

  • Thessaloniki
  • Meteora
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Drive 240 km, 3 hours 33 min

  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Monastery of Varlaam
  • Main Observation Deck of Meteora
  • Natural History Museum of Meteora and Mushroom Museum
  • Greek Education Museum
  • More

On day 3 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 2 destinations, Kastraki and Kalambaka. When you’re not sightseeing, take time to relax at your selected hotel in Kalambaka, where you’ll be staying for 1 night.

Get ready to discover some of the most iconic wonders in Thessaloniki, including a monastery, an observation deck, and a museum. Start your day at Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour. This breathtaking monastery is a locally appreciated place to see in Thessaloniki. Then, wander over to Monastery Of Varlaam. If UNESCO world heritage-listed sites excite you, this monastery will be right up your alley. Nearby, you’ll also find Main Observation Deck Of Meteora. This eye-catching observation deck is a favorite among visitors.

Thessaloniki offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Natural History Museum Of Meteora And Mushroom Museum is an increasingly popular spot in the village that will captivate you with its unique charm. When you’re done at the museum, don’t forget to check out the eye-catching Greek Education Museum. Take a moment to appreciate the fascinating details of this increasingly popular museum.

At the end of the day, you will drive to Kalambaka, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Kalambaka's best restaurants.

Say good night to Kalambaka and look forward to another great day of your road trip in Greece!

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Day 4

Day 4

  • Meteora
  • Ioannina
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Drive 106 km, 2 hours 26 min

  • Silversmithing Museum
  • Ich Kale Acropolis of Ioannina
  • Museum "Arslan Pasha"
  • Ioannina Castle
  • Litharitsia park
  • The Clock Tower of Ioannina
  • More

On day 4 of your road trip in Greece, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Ioannina. In the evening, you’ll end up in Ioannina, where you will stay for 1 night.

A blend of family-friendly attractions, picturesque spots, and historic treasures await you in Kalambaka on today’s itinerary. First up is the up-and-coming museum, Silversmithing Museum Of Ioannina. Afterward, continue to Ic Kale Acropolis Of Ioannina, an archeological site every traveler should visit.

As you explore Kalambaka’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Museum "arslan Pasha". This frequently visited point of interest is an essential stop. Following that, head to Ioannina Castle, another must-visit site that will enhance your experience. Don’t forget to stop by Litharitsia Park, an up-and-coming park in the city. Finally, end your day with a visit to The Clock Tower Of Ioannina, a breathtaking monument that offers the perfect conclusion to your sightseeing of the day.

When you’re done exploring for the day, you’ll drive to your hotel in Ioannina. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Ioannina. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a fantastic dining experience at To Dodeka Cafe Bar, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Mustagogia offers an enticing alternative with its varied menu. Additionally, Accademia Del Panino is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Ioannina.

Cap off your dinner by heading to ⚜ V E D E M A ⚜, ideal for a leisurely evening with a drink in hand. Hogwarts Tales And Spirits is another bar that offers an enjoyable setting. Similarly, Chevalier is also a popular place to go on a night out, perfect for relaxing and socializing.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Greece.

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Day 5

Day 5

  • Ioannina
  • Thessaloniki
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Drive 270 km, 3 hours 53 min

  • Καταρράκτης Ανήλιου
  • Averoff Art Gallery
  • Metsovo square
  • Metsovo Folk Art Museum (Tossizza Mansion)
  • Αβερώφειος Κήπος
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Dive into day 5 of your remarkable road trip in Greece. Today you will explore Anilio and Metsovo, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Thessaloniki. You’ll stay here for 1 night.

Bring your curiosity for today’s adventure around Ioannina. Some of the village’s most loved attractions await! Katarraktis Anilioy is the perfect place to start. This waterfall is one of the most frequently visited places to visit in Ioannina. Next, head to Averoff Art Gallery, an intriguing art gallery, known for its visually striking features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Metsovo Square. This romantic public square is a highly recommended experience. Nearby, you'll also find Metsovo Folk Art Museum (tossizza Mansion) and Averofeios Kipos. Visit these for an interesting touch to your journey.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Thessaloniki. Thessaloniki offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Thessaloniki's most popular restaurants, and connect with friendly locals for an authentic adventure.

Dine in style at Enoches Bar, a top recommendation for dinner tonight. Or, for a change of pace, O Loytros boasts a menu that's sure to impress. Also, be sure to check out rOOTS. Known as a local hotspot, it’s a great choice for tonight in Thessaloniki.

Let the evening flow smoothly from dinner to drinks at Peiratis Cafe-bar, a top-rated bar in the area. For other recommendations, In Rock Cafe Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Tribeca offers a memorable night with diverse drink options and excellent service.

Savor another day of unforgettable experiences in Greece!

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Day 6

Day 6

  • Thessaloniki - Departure day
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  • Arch of Galerius
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Day 6 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Arch Of Galerius And Rotunda. This notable monument is a popular place to see in the city.

Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

Dine in style at Millet, a top recommendation for dinner tonight. Or, for a change of pace, Agora Ouzeri boasts a menu that's sure to impress.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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