10-Day Italy Self-Drive Road Trip With Itinerary from Rome traveling north to Florence, Siena, La Spezia, and Venice
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Experience the freedom of the open road in Italy as you embark on an unforgettable 10-day road trip! This experience caters to every traveler, featuring destinations like Rome, Florence, Pisa, Siena, Castellina in Chianti, Corniglia, Manarola, Riomaggiore, La Spezia, Venice, and Verona.
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Rome, 2 nights in Florence, 2 nights in Siena, 1 night in La Spezia, and 1 night in Venice. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Rome, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of Rialto Bridge.
As you hit the open road and drive through Rome, Florence, Pisa, Siena, Castellina in Chianti, Corniglia, Manarola, Riomaggiore, La Spezia, Venice, and Verona, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
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Day 1
- Rome - Arrival day
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- Palatine Hill
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Welcome to Rome, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 2 nights immersing yourself in Rome's charm before embarking on the next leg of your journey.
Rome is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Palatine Hill, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Find your way to your hotel in Rome. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.
Make sure to reserve a table at La Bottega Roma, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Pasta In Corso, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Trattoria Vecchia Roma, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
After your meal, keep the night alive at a bar like La Botticella Of Poggi Giovanni, known for its lively atmosphere. Almalu Trastevere is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Bar Viminale Di Pepi Maurilio offers an excellent atmosphere for those looking to amp up the evening.
Raise a toast to the start of your 10-day road trip in Italy!
Day 2
- Rome
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Drive 6 km, 1 hour 24 min
- Colosseum
- Roman Forum
- Trevi Fountain
- Spanish Steps
- Piazza Navona
- Trastevere
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Day 2 offers a multitude of experiences. You will stay in Rome for 1 night more, offering you enough time to explore at a relaxed pace.
A top thing to do today is to explore Trastevere, a must-see neighborhood in Rome. It's the perfect starting point for touring the top attractions in the area.
Bring your curiosity for today’s adventure around Rome. Some of the city’s most loved attractions await! Colosseum is the perfect place to start. This archeological site is one of the most timeless places to visit in Rome. Next, head to Roman Forum, a world-famous archeological site, known for its breathtaking features.
In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Trevi Fountain. This romantic monument is a highly recommended experience. Nearby, you'll also find Spanish Steps and Piazza Navona. Visit these for an interesting touch to your journey.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
Shop 'til you drop at Rome's premier shopping hotspot, Trastevere! Elevate your style by browsing through trendy boutiques and shops, filled with unique finds. Keep an eye out for artisan crafts, perfect as cherished mementos. Trastevere also offers more, including attractions, key services, and exciting local experiences to round out your visit.
As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Enjoy a delicious meal at RomAntica, a highly-rated dining destination in Rome. If you're eager to try something different, consider Coso Ristorante, another top spot with a tantalizing menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.
Unwind after your meal by stepping into Sant' Eustachio Caffè. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Yellowsquare Rome offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Caffè Portofino, another top-rated bar in the area.
Savor another day of unforgettable experiences in Italy!
Day 3
- Rome
- Florence
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Drive 281 km, 3 hours 51 min
- piazzale Michelangelo
- Basilica of Santa Croce in Florence
- Uffizi Gallery
- Ponte Vecchio
- Piazza della Repubblica
- piazza della Signoria
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Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Florence. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Florence. You will spend 2 nights here for some well-deserved relaxation.
Today, you'll explore some of the most beautiful places in Rome, including an observation deck, a church, an art gallery, a historical landmark, a public square and much more! Start your day with a visit to Piazzale Michelangelo. This famous observation deck is a must-visit in the city. When you’re ready for your next discovery, continue to Basilica Of Santa Croce In Florence, which may be one of the most culturally significant places you will experience today.
One of the best things about exploring Rome on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Uffizi Gallery, an extraordinary art gallery in the city. If you’re up for more discoveries, don’t forget to reserve some time for Ponte Vecchio and Piazza Della Repubblica. End your day with a visit to Piazza Della Signoria, an astonishing public square that’s sure to leave a lasting impression.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Enjoy a delicious meal at Ristorante Oliviero 1962, a highly-rated dining destination in Florence. If you're eager to try something different, consider Di Poneta Novoli, another top spot with a tantalizing menu. You might also want to secure a reservation at Caffe San Firenze. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Florence this evening.
If you’re not ready to end the night just yet, Manifattura offers a perfect venue to relax and savor a drink. Similarly, Se·sto On Arno Rooftop Bar is well-suited for those looking to unwind in a social setting. Il Vinile is another excellent spot to enjoy a nightcap after a delightful meal.
As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.
Day 4
- Florence
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Drive 196 km, 3 hours 5 min
- Palazzo Blu
- Knights' Square
- Palazzo della Carovana
- Leaning Tower of Pisa
- Pisa Cathedral
- Piazza del Duomo, Pisa
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On day 4 of your road trip in Italy, you’ll start and end your day in Florence, but spend the day exploring what’s beyond the city. Since you will return to Florence for 1 night more, there’s no need to rush. Experience Pisa to the fullest today with this curated day itinerary!
Set out on a day brimming with fun adventures, photo-friendly spots, and history-rich sites. Start at the worthwhile Palazzo Blu, an instagrammable art gallery in Florence. Next, go to Knights' Square.
After visiting Palazzo Blu and Knights' Square, have a stroll along Florence's streets and take in the local charm. Continue your sightseeing by heading to Palazzo Della Carovana. This symbolic palace offers a unique experience. Leaning Tower Of Pisa is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Pisa Cathedral, one of the most stunning places to visit in Florence. If you still have some time left for sightseeing, we also recommend stopping by Piazza Del Duomo, Pisa.
When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.
Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.
Enjoy a lovely meal at Ditta Artigianale, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Trattoria Da Burde is another top choice with a popular menu. You could also check for a table at Casa Toscana. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Florence tonight.
After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Bar 50 Rosso, a well-loved spot among locals and tourists. Or, head to Bitter Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Archea Brewery, another top-rated place in the area.
Savor another day of unforgettable experiences in Italy!
Day 5
- Florence
- Siena
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Drive 79 km, 1 hour 28 min
- Basilica of San Domenico
- Fontebranda
- Siena Cathedral
- Pubblico Palace
- piazza del Campo
- Tower of Mangia
- More
Embark on another extraordinary experience on day 5 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Siena. At the end of the day, you will enjoy the comforts of a top-rated hotel in Siena, which will be your home away from home for 2 nights.
Immerse yourself in Florence’s rich culture with today's sightseeing itinerary. Start your journey at Basilica Of San Domenico. This breathtaking church is sure to ignite your curiosity. Next, dive into the heritage-rich features of Fontebranda, a must-visit historical landmark in the city.
In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Siena Cathedral, a captivating church. For a change of scene, check out Pubblico Palace, known for its culturally significant features. We also recommend visiting Piazza Del Campo. This public square is a must for anyone looking to experience the city to the fullest. Lastly, end your day with a visit to Tower Of Mangia, yet another locally appreciated attraction in Florence.
When you’re done exploring for the day, you’ll drive to your hotel in Siena. Check in and spend some time relaxing before you head out to tour the city.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Siena. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Treat yourself to a delightful dinner at Enoteca I Terzi, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Ristorante Tar-Tufo? It's another excellent option with a diverse menu. Consider reserving a table at Antica Trattoria Papei as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Siena.
Explore the vibrant nightlife at Meet Life Cafè after your meal, a hub for lively evenings and memorable moments. Or, head to Maudit Pub for a great selection of flavorful drinks and a charming setting. Furthermore, Bar Impero Siena is perfect for those looking to extend their night with a touch of local flavor.
Relax and recharge in preparation for another adventurous day in Italy!
Day 6
- Siena
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Drive 76 km, 2 hours 7 min
- Winery San Giorgio a Lapi
- Castello di Brolio
- Poggio Amorelli
- Tumulo di Montecalvario
- Rocca di Castellina in Chianti
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Wake up to day 6 of your extraordinary road trip in Italy. With 1 night left in Siena, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!
Siena is brimming with adventures. Today’s wonderful stops include a winery, a castle, and an archeological site. Begin your sightseeing adventure at the frequently visited Winery San Giorgio A Lapi and allow yourself time to explore. Just a short distance away you'll find your next stop, Castello Di Brolio, a visually striking castle that draws visitors from far and near.
Continue your journey to Poggio Amorelli, one of the city’s most intriguing spots that you shouldn’t miss. Another great site to visit is the increasingly popular Tumulo Di Montecalvario. When you're finished at the archeological site, Rocca Di Castellina In Chianti awaits your visit. This castle is a romantic highlight on today's itinerary.
When you’re done exploring for the day, you’ll return to Siena and your accommodation.
As dinnertime approaches, it's time to head out for a bite to eat in Siena. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Make sure to reserve a table at Osteria Quattro Venti, an iconic dining spot in Siena. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Fischi per Fiaschi, a popular restaurant in Siena. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Osteria da Divo, a hidden gem nestled in Siena. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
After your delicious meal, get a taste of the vibrant nightlife with a visit to Charlie Mixology Bar Di Aldinucci Riccardo, known for its inviting atmosphere. Bar Pinacoteca is another great option if you’re looking for a place to get the night started. Similarly, San Paolo Pub provides a great setting to enjoy the night away.
As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.
Day 7
- Siena
- La Spezia
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Drive 259 km, 4 hours 21 min
- Cinque Terre National Park
- Manarola Overlook Viewpoint
- Chiesa di San Lorenzo
- Riomaggiore
- More
On day 7 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Corniglia, Manarola, and Riomaggiore. In the evening, you’ll end up in La Spezia, where you will stay for 1 night.
Start by visiting Cinque Terre National Park, a prime spot to begin your journey. This romantic national park is sure to impress. Next on your list is Manarola Overlook Viewpoint, another must-visit landmark and underrated observation deck renowned for its romantic features.
While exploring and sightseeing, take time to savor the culture of Siena by sampling some local delicacies. When you’re ready for more sightseeing, head to Chiesa Di San Lorenzo. This inviting church is an essential place to visit for anyone looking for the full Siena experience. We also recommend visiting Riomaggiore, an often recommended sightseeing destination.
At the end of the day, you will drive to La Spezia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
Indulge in a memorable dining experience at one of La Spezia's most popular restaurants, and connect with friendly locals for an authentic adventure.
Have a fantastic dining experience at The Colombaio Park, a highly recommended choice for tonight's dinner.
Savor another day of unforgettable experiences in Italy!
Day 8
- La Spezia
- Venice
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Drive 366 km, 4 hours 32 min
- Bridge of Sighs
- Doge's Palace
- St Mark's Basilica
- Grand Canal
- Rialto Bridge
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Dive into day 8 of your remarkable road trip in Italy. Today you will explore Venice, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Venice. You’ll stay here for 1 night.
Savor the day by visiting some of the best places to see in La Spezia, including a monument, a palace, a church, a street, a historical landmark and much more! Start your adventure at Bridge Of Sighs. This captivating monument is a must-visit for travelers looking for a unique holiday experience. Make your way to Doge's Palace located in La Spezia for another exciting encounter.
Next, immerse yourself in the setting of St Mark's Basilica. Its history-steeped features will captivate you. After the church, continue your tour of the city with a visit to Grand Canal. Visitors usually appreciate the history-steeped features of this street. Next up is Rialto Bridge, a highly recommended historical landmark.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Venice. Venice offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As dinnertime approaches, it's time to head out for a bite to eat in Venice. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Enjoy a lovely meal at Bauer Hotel, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, L'Osteria Le Guglie is another top choice with a popular menu. You could also check for a table at Corner Pub. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Venice tonight.
Keep the evening going at Al Parlamento, a great choice for enjoying the after-dinner hours with a drink. You could also go to The Caffe Rosso, which offers a similarly pleasant setting and great drinks. Another option is Adagio, which provides an inviting environment for unwinding after a busy day out.
Raise your glass to another unforgettable day in Italy!
Day 9
- Venice
- Rome
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Drive 632 km, 7 hours 4 min
- Ponte Pietra
- Scaliger Tombs
- piazza delle Erbe
- Verona Arena
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On day 9 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Verona. When you’re not sightseeing, take time to relax at your selected hotel in Rome, where you’ll be staying for 1 night.
Get ready for a day filled with family-friendly attractions, romantic experiences, and scenic views in the charming city of Venice. Your adventure starts at Ponte Pietra, a popular local hot spot. Another notable attraction to explore is Scaliger Tombs. This underrated monument is known for its enchanting appeal.
After soaking in the highlights of these sights, take some time to wander Venice's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Piazza Delle Erbe. This romantic public square offers a fascinating experience that many visitors find memorable. Verona Arena is also worth visiting.
When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.
After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.
Make sure to reserve a table at Hotel de Russie, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of La Taverna Italiana, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of The Parrot Bar, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
Cap off your dinner by heading to The Apartment Bar Roma, ideal for a leisurely evening with a drink in hand. Hotel Hassler Roma is another bar that offers an enjoyable setting.
Celebrate another amazing day of your road trip adventure in Italy!
Day 10
- Rome - Departure day
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- Pantheon
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Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Rome before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, we recommend visiting Pantheon, a culturally significant monument before you head out.
Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones. For those seeking luxury items, check out the area’s high-end stores.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Rome.
You’ll then say farewell to Rome. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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