5-Day Sicily Self-Drive Road Trip With Itinerary from Palermo to Agrigento and Taormina

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Escape the ordinary with this exciting 5-day road trip through Sicily. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in Sicily takes you through some of the best places to see in the country. You will spend 2 nights in Palermo, 1 night in Agrigento, and 1 night in Taormina. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Palermo, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Valle Dei Templi and Palermo Cathedral are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Ancient Theatre Of Taormina, learn more about the unique Quattro Canti, and immerse yourself in the vibrant atmosphere of Norman Palace.

As you hit the open road and drive through Palermo, Agrigento, Piazza Armerina, Taormina, Syracuse, and Cefalù, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Foro Italico
Norman PalacePalermo CathedralQuattro CantiFontana PretoriaOrto botanico di PalermoValle dei Templi
Villa Romana del CasaleGrotta AzzurraVilla Comunale di TaorminaAncient theatre of TaorminaPorta CataniaBasilica of St. Nicholas of Bari
Ear of DionysiusNeapolis Archaeological ParkTemple of ApolloCathedral of CefalùLavatoio Medievale Fiume Cefalino - Cefalù (pa)
Catacombe dei Cappuccini

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Day 1

Day 1

  • Palermo - Arrival day
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  • Foro Italico
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Your road trip adventure in Sicily begins as soon as you reach Palermo and pick up your car. You’ll stay in Palermo for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Palermo is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Foro Italico, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Palermo. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Palermo, it's often a good idea to reserve a table in advance.

Dine in style at Cotto e Bollito, a top recommendation for dinner tonight. Or, for a change of pace, Bebop boasts a menu that's sure to impress. Also, be sure to check out Eremiti Restaurant. Known as a local hotspot, it’s a great choice for tonight in Palermo.

Keep the evening going at Malox Cult, a great choice for enjoying the after-dinner hours with a drink. You could also go to Ai Giudici, which offers a similarly pleasant setting and great drinks. Another option is Bar Italico, which provides an inviting environment for unwinding after a busy day out.

Raise a toast to the start of your 5-day road trip in Sicily!

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Day 2

Day 2

  • Palermo
  • Agrigento
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Drive 138 km, 2 hours 53 min

  • Norman Palace
  • Palermo Cathedral
  • Quattro Canti
  • Fontana Pretoria
  • Orto botanico di Palermo
  • Valle dei Templi
  • More

On day 2 of your road trip in Sicily, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Palermo and Agrigento. In the evening, you’ll end up in Agrigento, where you will stay for 1 night.

Discover a day packed with family-friendly attractions, breathtaking views, and picturesque spots in Palermo. Begin your sightseeing with Norman Palace. This captivating palace is one of the top attractions in the city. Proceed to Palermo Cathedral, another must-visit attraction.

As you wander through the inviting streets of Palermo, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Quattro Canti. This notable public square is a traveler-favorite. Not far away, you’ll find Fontana Pretoria, another key site on your sightseeing itinerary. Orto Botanico Di Palermo is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers. Conclude your day at Valle Dei Templi and uncover why it's recognized as one of the city's most notable attractions.

At the end of the day, you will drive to Agrigento, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Agrigento's most popular restaurants, and connect with friendly locals for an authentic adventure.

Make sure to reserve a table at Ambasciata di Sicilia, an iconic dining spot in Agrigento. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Le Cuspidi, a popular restaurant in Agrigento. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Yellove RistoVintage, a hidden gem nestled in Agrigento. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Head back to your accommodation in Agrigento and get some rest in preparation for another magical day of your road trip in Sicily!

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Day 3

Day 3

  • Agrigento
  • Taormina
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Drive 252 km, 4 hours 32 min

  • Villa Romana del Casale
  • Grotta Azzurra
  • Villa Comunale di Taormina
  • Ancient theatre of Taormina
  • Porta Catania
  • Basilica of St. Nicholas of Bari
  • More

On day 3 of your exciting self-drive vacation in Sicily, you’ll soak in the magnificence of 3 destinations, Piazza Armerina, Mazzarò, and Taormina. When you’re not sightseeing, take time to relax at your selected hotel in Taormina, where you’ll be staying for 1 night.

Prepare for a day full of fun adventures, scenic views, and photo-friendly spots. When you’re ready, kick off your sightseeing adventure at Villa Romana Del Casale. This captivating archeological site is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Grotta Azzurra, one of the town’s best highlights.

Next, check out Villa Comunale Di Taormina, one of the most locally appreciated places to see in Agrigento. This park is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Ancient Theatre Of Taormina. Wander around and soak in the visually striking atmosphere this archeological site offers. Then, head to Porta Catania, a top-rated monument that adds another dimension to your day. Finally, visit the worthwhile Basilica Of St. Nicholas Of Bari, the last of our attraction recommendations for today.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Taormina. Taormina offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Taormina. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a fantastic dining experience at PizzaMania Taormina, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Ristorante Pizzeria Tiramisù Taormina offers an enticing alternative with its varied menu. Additionally, La Pignolata Guinness Cannoli Taormina since 1978 N°15 is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Taormina.

Continue your lively evening at Luraleo Bar, a perfect place for winding down or revving up the night, depending on which mood you’re in. Don Diego Gelateria Caffetteria is another excellent bar that offers a great selection of drinks to suit any mood.

Raise your glass to another unforgettable day in Sicily!

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Day 4

Day 4

  • Taormina
  • Palermo
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Drive 424 km, 5 hours 25 min

  • Ear of Dionysius
  • Neapolis Archaeological Park
  • Temple of Apollo
  • Cathedral of Cefalù
  • Lavatoio Medievale Fiume Cefalino - Cefalù (pa)
  • More

Dive into day 4 of your remarkable road trip in Sicily. Today you will explore Syracuse and Cefalù, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Palermo. You’ll stay here for 1 night.

Get ready for an exciting day in Taormina. Today’s sightseeing agenda includes a cave, an archeological site, a church, a historical landmark and much more! Begin your adventure at Ear Of Dionysius. This is a beloved cave you should not miss. Another must-see is Neapolis Archaeological Park, a popular archeological site in Taormina.

When you’re ready for the next sight, head to Temple Of Apollo. From there, take a leisurely stroll to Cefalù Cathedral, another of the city’s locally renowned attractions. We recommend continuing your self-guided tour at Lavatoio Medievale Fiume Cefalino - Cefalù (pa), an eye-catching place of interest in the city.

When you’re done exploring for the day, you’ll drive to your hotel in Palermo. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Palermo. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Osteria Mercede, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Trattoria Del Massimo is another top choice with a popular menu. You could also check for a table at Grand Hotel Piazza Borsa. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Palermo tonight.

Following your dinner, dive into the local bar culture at Spina Bar Palermo. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Torrefazione Castagnetta Massimiliano (gelateria), the perfect place for those looking to experience the best of the nightlife. Similarly, Monkey Pub provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Savor another day of unforgettable experiences in Sicily!

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Day 5

Day 5

  • Palermo - Departure day
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  • Catacombe dei Cappuccini
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Day 5 of your road trip in Sicily is your departure day. This is your chance to catch a last glimpse of Palermo before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Catacombe Dei Cappuccini. This popular cemetery is a popular place to see in the city.

Maximize your last day in Sicily and go on a shopping spree in Palermo’s shopping center. Browse for souvenirs to remind you of your wonderful journey in Sicily.

Before you conclude your road trip in Sicily, drop by another restaurant for a last chance at a memorable dining experience in Palermo.

Enjoy a lovely meal at Splendid Hotel la Torre, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Ristorantino Sobremesa is another top choice with a popular menu.

You’ll then say farewell to Palermo. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

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