6-Day Italy Self-Drive Road Trip With Itinerary from Rome traveling east to Salerno and Naples

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Photo of piazza de spagna in Rome, Italy.
Photo of Fountain di Trevi in Rome, Italy.
Bridge Il Tevere a Ponte Vittorio Emanuele II in Rome, Italy.
Hadrian Mausoleum, Rome, Italy.
 Vatican dome of San Pietro and Sant Angelo Bridge, over Tiber river in Rome, Italy.
panoramic view of Rome and St. Peter's Basilica, Italy.
View of Pantheon in the morning, Rome, Italy.
Rome, Italy. Stunning twilight view of Forum ancient ruins, seen from Capitoline hill with Colosseum in background.
Aerial view of forum romanum and surrounding areas of historical centre of italian capital rome.
Cozy old street in Trastevere in Rome, Italy. Trastevere is rione of Rome, on the west bank of the Tiber in Rome, Lazio, Italy. Architecture and landmark of Rome.
Aerial panorama of St. Peter's Square in Vatican with Rome in the background. Italy.
photo of view of Illuminated Fontana Di Trevi, Trevi Fountain at Dusk, Rome, Italy.
photo of view of Spanish Step, Rome, Italy.
photo of view of Museum Luasanne, Rome, Italy.
photo of view Roma Wall of Lugo, Rome, Italy.
photo of view of Roman Bridge Cordoba, Rome, Italy.
photo of view of Roman ruins in Rome, Forum, Rome, Italy.
photo of view of Roman Bridge of Cordoba, Rome, Italy.
photo of view of The Iconic, the legendary Coliseum of Rome, Italy.
photo of view of Rome, Italy: The Roman Forum, Latin: Forum Romanum, Italian: Foro Romano, Rome, Italy.
photo of view of Trevi Fountain (Fontana di Trevi) in Rome, Italy. Trevi is most famous fountain of Rome. Architecture and landmark of Rome, Postcard of Rome, Italy.
Beautiful view of Vietri sul Mare, the first town on the Amalfi Coast, with the Gulf of Salerno, province of Salerno, Campania, southern Italy.
Panoramic view of small town Atrani on Amalfi Coast in province of Salerno, Campania region, Italy.
Long focus picture of Maiori port. Splendid seascape of Mediterranean seascape, Amalfi coast in the province of Salerno, Italy, Europe.
City of Positano on Amalfi coast in the province of Salerno, Campania, Italy.
A girl in a cowboy hat with a backpack enjoys an incredibly beautiful view of a stone bridge over the gorge Fiordo di Furore.
Tourists on the beach, Amalfi, Province Of Salerno, Gulf Of Salerno, Tyrrhenian Sea, Campania, Italy.
Amalfi - seaside town in the Gulf of Salerno in the Italian province of Salerno, the heart of the Amalfi coast.
Old chapel in Santa Maria di Castellabate town. Impressive summer scene of province of Salerno in the Campania region.
photo of view of Aerial view of the Italian city of Salerno. Salerno is a city and port on the Tyrrhenian Sea in southern Italy, the administrative center of the Salerno province of the Campania region.
photo of view of  Blue sea and beach in Minori, seaside town at Amalfi Coast, province of Salerno, in Campania region of south-western Italy. Amalfitana is most popular travel and holiday destination in Europe
photo of view of Beautiful view to Amalfi coast from Ravello town, Italy travel photo, sunny Salerno province.
photo of view of Panoramic view of small town Atrani on Amalfi Coast in province of Salerno, Campania region, Italy. Amalfi coast is popular travel and holyday destination in Italy. Ripe yellow lemons in foreground.
photo  of view of Beautiful view of famous Paestum Temples Archaeological UNESCO World Heritage Sitein in scenic golden evening light at sunset, Province of Salerno, Campania, Italy
photo of view of Town Atrani, Peninsula of Sorrento, Campania, Gulf of Salerno, Italy, Europe. Town Atrani, Amalfi Coast, Peninsula of Sorrento, Campania, Gulf of Salerno, Italy.
photo  of view of   Salerno, Italy cityscape over Piazza Vittorio Veneto and the main station at dawn. (The 1923 War Monument translation: To the fallen of Salerno Province. 1915-1918. 1935,1936, 1940-1945)
photo of view of Amalfi - seaside town in the Gulf of Salerno in the Italian province of Salerno, the heart of the Amalfi coast - a UNESCO World Heritage Site. Italy.
Twilight panorama of Naples in Italy
Photo of Morning view of Amalfi cityscape on coast line of mediterranean sea, Italy.
Photo of View of Piazza del Plebiscito, Naples,Italy.
Panoramic view of the ancient city of Pompeii with houses and streets. Pompeii is an ancient Roman city died from the eruption of Mount Vesuvius in the 1st century. Naples, Italy.
Photo of Panorama of Naples, view of the port in the Gulf of Naples and Mount Vesuvius. The province of Campania. Italy.
Photo of Maschio Angioino Castle in Naples during a sunny sunrise.
Photo of Obelisk Guglia of the Immaculate Virgin on Piazza Gesu Nuovo in Naples (Napoli), Italy.
Photo of Boats at Marina Grande embankment in Capri Island in Tyrrhenian sea, Italy.
Photo of Stunning rooftop view of Naples from above during sunset.
Photo of Kilometers-long promenade along cascades at the Palace of Caserta, Italy.
Photo of The neighborhood called Quartieri Spagnoli in Naples, Italy. Street view of old town. Narrow street of Napoli. Bright sunny day. Gulf of Naples, blue sky, sea on background. Cacti on the terrace.
Photo of Sunset in Positano, Amalfi Coast, Salerno - Naples, Italy.
Photo of Ancient ruins of Pompei city (Scavi di Pompei), Naples, Italy.
photo of view of Colorful architecture in Naples city, Italy. Summer cityscape at sunset. Famous travel destination.
photo of view of Panoramic view of Naples city and Gulf of Naples, Italy. Blue sea and the sky with clouds at sunset. Famous travel destination.
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Explore the best of Italy on a 6-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Rome, Salerno, Amalfi, Pompei, and Naples. This road trip itinerary in Italy seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Rome, 1 night in Salerno, and 1 night in Naples. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Rome, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.

As you hit the open road and drive through Rome, Salerno, Amalfi, Pompei, and Naples, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Piazza Navona
Castel Sant'AngeloPantheonTrevi FountainPiazza di SpagnaSpanish Steps
Roman ForumColosseumpiazza del PopoloVilla Borghese
Cattedrale di Santa Maria degli Angeli, San Matteo e San Gregorio VIIAmalfi CoastArchaeological Park of PompeiiTemple of VenusBasilica
piazza del PlebiscitoSt Peter's Basilica
Altare della Patria

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Day 1

Day 1

  • Rome - Arrival day
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  • Piazza Navona
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Say hello to Rome! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Rome for 2 nights before you continue your adventure!

Rome is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Piazza Navona, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Rome. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at La Bottega Roma, a top-rated dining spot in Rome. If you're in the mood for something new, try Pasta In Corso, another premier location with a delectable menu. You might also want to book a table at Trattoria Vecchia Roma. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.

If you’re not ready to end the night just yet, La Botticella Of Poggi Giovanni offers a perfect venue to relax and savor a drink. Similarly, Almalu Trastevere is well-suited for those looking to unwind in a social setting. Bar Viminale Di Pepi Maurilio is another excellent spot to enjoy a nightcap after a delightful meal.

Raise a toast to the start of your 6-day road trip in Italy!

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Day 2

Day 2

  • Rome
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Drive 13 km, 1 hour 8 min

  • Castel Sant'Angelo
  • Pantheon
  • Trevi Fountain
  • Piazza di Spagna
  • Spanish Steps
  • More

Day 2 of your road trip will take you to the best attractions Rome has to offer. Cherish the 1 night you have left in Rome by discovering the best things there are to see and do in the city.

Brace yourself for today’s incredible lineup of attractions in Rome, featuring fun adventures, romantic experiences, and scenic views. Start at Castel Sant'angelo, a widely recognized castle in the city. Then, head to Pantheon and soak in the ambiance of this standout monument.

There are many interesting places to see in Rome, and when you are ready for more, go to Trevi Fountain. This is one of the city’s most iconic majestic spots of interest. After exploring the monument, visit the globally renowned Piazza Di Spagna. Not far away, you'll also find Spanish Steps. This public square is an enchanting highlight in Rome.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Experience shopping bliss at Rome as you explore Galleria San Pietro. Take a leisurely stroll through unique and shops, where local treasures are waiting to be found. Beyond shopping, Galleria San Pietro offers more options, including unique attractions, key services, and vibrant events.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Experience a taste of local culinary excellence while in Rome by securing a table at La Pergola. An esteemed 3-star Michelin restaurant, it features an exceptional mediterranean and contemporary menu. For an alternative taste experience, visit Il Pagliaccio, famous for its scrumptious creative and innovative dishes. This 2-star Michelin venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover Enoteca La Torre, a local favorite celebrated for its exquisite mediterranean and creative cuisine in Rome. Located in the heart of the city, this 2-star Michelin restaurant is an ideal pick for mediterranean and creative cuisine lovers seeking top-notch culinary experiences.

Continue your lively evening at Sant' Eustachio Caffè, a perfect place for winding down or revving up the night, depending on which mood you’re in. Yellowsquare Rome is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Caffè Portofino ensures a night out tailored to your taste.

Raise your glass to another unforgettable day in Italy!

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Day 3

Day 3

  • Rome
  • Salerno
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Drive 277 km, 3 hours 35 min

  • Roman Forum
  • Colosseum
  • piazza del Popolo
  • Villa Borghese
  • More

Dive into day 3 of your remarkable road trip in Italy. Today you will explore Rome, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Salerno. You’ll stay here for 1 night.

Prepare for a day full of fun adventures, breathtaking views, and picturesque spots. When you’re ready, kick off your sightseeing adventure at Roman Forum. This wondrous archeological site is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Colosseum, one of the city’s best highlights.

Next, check out Piazza Del Popolo, one of the most extraordinary places to see in Rome. This public square is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Villa Borghese. Wander around and soak in the serene atmosphere this park offers.

When you’re done exploring for the day, you’ll drive to your hotel in Salerno. Check in and spend some time relaxing before you head out to tour the city.

As you explore more of Salerno, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Start your culinary exploration in Salerno by securing a reservation at Re Maurì. This renowned restaurant holds 1 Michelin star and offers an exceptional menu of creative cuisine. Immerse yourself in the culinary delights of L'Unico Drink & Food Salerno, a popular restaurant in Salerno. With a menu designed to delight, it ensures a dining experience that transcends the ordinary.

Keep the evening going at Hilton Bar E Gastronomia, a great choice for enjoying the after-dinner hours with a drink. You could also go to The Black Monday Speakeasy Tbm, which offers a similarly pleasant setting and great drinks. Another option is Dòmo I' Vinaino Wine Bar - Enogastronomia, which provides an inviting environment for unwinding after a busy day out.

Head back to your accommodation in Salerno and get some rest in preparation for another magical day of your road trip in Italy!

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Day 4

Day 4

  • Salerno
  • Naples
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Drive 88 km, 2 hours 39 min

  • Cattedrale di Santa Maria degli Angeli, San Matteo e San Gregorio VII
  • Amalfi Coast
  • Archaeological Park of Pompeii
  • Temple of Venus
  • Basilica
  • More

Embark on another extraordinary experience on day 4 of your road trip in Italy. Today, you will make 3 stops and experience some of the highlights of Salerno, Amalfi, and Pompei. At the end of the day, you will enjoy the comforts of a top-rated hotel in Naples, which will be your home away from home for 1 night.

Bring your curiosity for today’s adventure around Salerno. Some of the city’s most loved attractions await! Cathedral Of Santa Maria Degli Angeli, San Matteo And San Gregorio Vii is the perfect place to start. This church is one of the most intriguing places to visit in Salerno.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Archaeological Park Of Pompeii. This UNESCO world heritage-listed archeological site is a highly recommended experience. Nearby, you'll also find Temple Of Venus and Basilica. Visit these for an interesting touch to your journey.

At the end of the day, you will drive to Naples, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Naples's best restaurants.

Treat yourself to an extraordinary dining experience at Veritas, a 1-star Michelin restaurant offering an incredible campanian and contemporary menu. Alternatively, if your taste buds call for something different, Il Comandante is one of the best restaurants for creative and mediterranean cuisine in Naples. This 1-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at ARIA. As a top-rated establishment with 1 Michelin star, it is an ideal choice for contemporary and modern cuisine in the city.

Round off your dining experience by visiting Happening Cocktail Bar, a prime location for a drink. Alternatively, explore the distinctive characteristics of Shanti Art Musik Bar, a bar catering to every mood and preference. Gran Caffè Gambrinus likewise offers a unique atmosphere, perfect for a memorable night out.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

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Day 5

Day 5

  • Naples
  • Rome
  • More

Drive 238 km, 2 hours 56 min

  • piazza del Plebiscito
  • St Peter's Basilica
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On day 5 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Naples and Vatican City. When you’re not sightseeing, take time to relax at your selected hotel in Rome, where you’ll be staying for 1 night.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Naples allows for both. Start by heading to Piazza Del Plebiscito. This impressive public square provides an insightful glimpse into the city's identity.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a lovely dining experience at Hotel de Russie, a popular restaurant in Rome. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Rome at La Taverna Italiana, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated The Parrot Bar. It’s yet another ideal choice to enhance your time in Rome tonight.

Continue your lively evening at The Apartment Bar Roma, a perfect place for winding down or revving up the night, depending on which mood you’re in. Hotel Hassler Roma is another excellent bar that offers a great selection of drinks to suit any mood.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 6

Day 6

  • Rome - Departure day
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  • Altare della Patria
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Day 6 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Rome before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Altare Della Patria, a remarkable monument before you head out.

As your final day in Italy unfolds, enjoy a last-minute shopping spree in Rome's best shopping area, Via del Corso. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Italy.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Rome.

You’ll then say farewell to Rome. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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