One-Week Italy Self-Drive Road Trip With Itinerary from Genoa to Florence

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Escape the ordinary with this exciting 8-day road trip through Italy. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 4 nights in Genoa and 3 nights in Florence. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Genoa, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Ponte Vecchio and Leaning Tower Of Pisa are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Piazza Del Duomo, Pisa, learn more about the unique Cathedral Of Santa Maria Del Fiore, and immerse yourself in the vibrant atmosphere of Piazza Della Signoria.

As you hit the open road and drive through Genoa, Riomaggiore, Manarola, Corniglia, Pisa, Florence, Siena, San Gimignano, and Lucca, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Via Garibaldi
porto anticoAquarium of GenoaGalata - Museo del mareLighthouse of Genoa
RiomaggioreManarola Overlook ViewpointCinque Terre National Park
Knights' SquareLeaning Tower of PisaPisa CathedralPiazza del Duomo, PisaCampo santo
Basilica of Santa Croce in FlorenceUffizi GalleryPonte VecchioPalazzo Vecchiopiazza della SignoriaCathedral of Santa Maria del Fiore
Tower of Mangiapiazza del CampoSiena CathedralPorta San GiovanniPiazza del Duomo, San Gimignano
Walls of LuccaPiazza NapoleoneSan Michele in ForoPiazza dell'AnfiteatroArea Marina Protetta di Portofino
piazza De Ferrari

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Day 1

Day 1

  • Genoa - Arrival day
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  • Via Garibaldi
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Welcome to Genoa, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 3 nights immersing yourself in Genoa's charm before embarking on the next leg of your journey.

Genoa is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Via Garibaldi, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Genoa. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Genoa, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at 7 Sensi cucina decontaminata, a highly-rated dining destination in Genoa. If you're eager to try something different, consider Alla Lunga Ristorante, another top spot with a tantalizing menu. You might also want to secure a reservation at Grand Hotel Savoia. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Genoa this evening.

Round off your dining experience by visiting Scurreria Beer & Bagel, a prime location for a drink. Alternatively, explore the distinctive characteristics of La Lepre, a bar catering to every mood and preference. Bar Pisacane Iii likewise offers a unique atmosphere, perfect for a memorable night out.

Raise a toast to the start of your 8-day road trip in Italy!

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Day 2

Day 2

  • Genoa
  • More

Drive 14 km, 1 hour 4 min

  • porto antico
  • Aquarium of Genoa
  • Galata - Museo del mare
  • Lighthouse of Genoa
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Day 2 of your road trip will take you to the best attractions Genoa has to offer. Cherish the 2 nights you have left in Genoa by discovering the best things there are to see and do in the city.

Discover a day packed with fun adventures, romantic experiences, and breathtaking views in Genoa. Begin your sightseeing with Porto Antico. This notable public square is one of the top attractions in the city. Proceed to Aquarium Of Genoa, another must-visit attraction.

As you wander through the inviting streets of Genoa, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Galata Museo Del Mare (complex). This beloved maritime museum is a traveler-favorite. Not far away, you’ll find Lighthouse Of Genoa, another key site on your sightseeing itinerary.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Genoa's best restaurants.

Savor the flavors at Zeffirino, a top pick for dinner tonight. Alternatively, Trattoria Vegia Zena beckons with its unique menu offerings. Also, consider Trattoria delle Grazie. With its consistent customer satisfaction, it’s an excellent option for dining in Genoa tonight.

Raise your glass to another unforgettable day in Italy!

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Day 3

Day 3

  • Genoa
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Drive 240 km, 4 hours 21 min

  • Riomaggiore
  • Manarola Overlook Viewpoint
  • Cinque Terre National Park
  • More

At the end of the day, you'll drive back to Genoa, where you'll stay for 1 night more.

Today's adventure in Genoa promises more breathtaking discoveries and enriching experiences! Begin at Riomaggiore. Then, enjoy Manarola Overlook Viewpoint, another romantic attraction that never fails to captivate visitors. Next, head over to Cinque Terre National Park, one of the village’s most captivating attractions, known for its UNESCO world heritage-listed features.

When you’re done exploring for the day, you’ll return to Genoa and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Genoa. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a delicious dinner at Osteria Sant'Ilario, an excellent option for tonight's dining. Looking for something different? La Cialtroneria offers a tantalizing alternative with its diverse menu. And don’t miss Manhattan Bar. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Genoa.

Head back to your accommodation in Genoa and get some rest in preparation for another magical day of your road trip in Italy!

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Day 4

Day 4

  • Genoa
  • Florence
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Drive 263 km, 3 hours 46 min

  • Knights' Square
  • Leaning Tower of Pisa
  • Pisa Cathedral
  • Piazza del Duomo, Pisa
  • Campo santo
  • More

Embark on another extraordinary experience on day 4 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Pisa. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 3 nights.

Today’s itinerary in Genoa covers several incredible sights, including a public square, a monument, a church, a cemetery and much more! Start your adventure at Knights' Square. This worthwhile public square is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the breathtaking wonders of Leaning Tower Of Pisa, a must-see monument in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Pisa Cathedral. This often recommended church offers an enriching experience. For a change of pace, head to Piazza Del Duomo, Pisa, where you can take in UNESCO world heritage-listed features. Conclude your self-guided sightseeing tour with a visit to Campo Santo. These sights offer a fulfilling end to a perfect day.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Dine in style at Ristorante Oliviero 1962, a top recommendation for dinner tonight. Or, for a change of pace, Di Poneta Novoli boasts a menu that's sure to impress. Also, be sure to check out Caffe San Firenze. Known as a local hotspot, it’s a great choice for tonight in Florence.

If you’re not ready to end the night just yet, Manifattura offers a perfect venue to relax and savor a drink. Similarly, Se·sto On Arno Rooftop Bar is well-suited for those looking to unwind in a social setting. Il Vinile is another excellent spot to enjoy a nightcap after a delightful meal.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 5

Day 5

  • Florence
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Drive 2 km, 36 min

  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • Palazzo Vecchio
  • piazza della Signoria
  • Cathedral of Santa Maria del Fiore
  • More

Day 5 offers a multitude of experiences. You will stay in Florence for 2 nights more, offering you enough time to explore at a relaxed pace.

Enjoy the perfect balance of relaxation and exploration in Florence today. One of the most captivating attractions included on the itinerary is Basilica Of Santa Croce In Florence. This inviting church will help you start your sightseeing on top. Then, take a leisurely stroll to Uffizi Gallery and learn what makes this history-steeped art gallery unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the wondrous Ponte Vecchio. After exploring the historical landmark, head to Palazzo Vecchio. This notable palace is a highlight in Florence. As your day continues, stop by Piazza Della Signoria, known for its visually striking features. Lastly, don’t forget to check out the widely recognized Cathedral Of Santa Maria Del Fiore. Enjoy exploring this incredible church at your own pace.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at Ditta Artigianale, a popular restaurant in Florence. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Florence at Trattoria Da Burde, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Casa Toscana. It’s yet another ideal choice to enhance your time in Florence tonight.

After savoring a delicious meal, step into the vibrant nightlife at Bar 50 Rosso, where the evening is just getting started. In the same way, Bitter Bar offers a unique charm perfect for experiencing the local bar scene in Florence. Archea Brewery is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

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Day 6

Day 6

  • Florence
  • More

Drive 181 km, 3 hours 16 min

  • Tower of Mangia
  • piazza del Campo
  • Siena Cathedral
  • Porta San Giovanni
  • Piazza del Duomo, San Gimignano
  • More

On day 6 of your road trip, you’ll start and end your day in Florence, where you'll stay for 1 night more.

Prepare for a day full of fun adventures, scenic views, and picturesque spots. When you’re ready, kick off your sightseeing adventure at Tower Of Mangia. This increasingly popular monument is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Piazza Del Campo, one of the city’s best highlights.

Next, check out Siena Cathedral, one of the most notable places to see in Florence. This church is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Porta San Giovanni. Wander around and soak in the historic atmosphere this monument offers. Then, head to Piazza Del Duomo, a top-rated public square that adds another dimension to your day.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Ristorante Buca Mario, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Agricola Toscana, another top spot with a mouthwatering menu. You might also want to secure a reservation at Eataly Firenze. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

Cap off your dinner by heading to Gosh*, ideal for a leisurely evening with a drink in hand. Antico Caffè Del Moro - Art Bar Firenze is another bar that offers an enjoyable setting. Similarly, Quelo Bar is also a popular place to go on a night out, perfect for relaxing and socializing.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 7

Day 7

  • Florence
  • Genoa
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Drive 261 km, 4 hours 20 min

  • Walls of Lucca
  • Piazza Napoleone
  • San Michele in Foro
  • Piazza dell'Anfiteatro
  • Area Marina Protetta di Portofino
  • More

Experience an unparalleled adventure on day 7 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Lucca and San Fruttuoso di Camogli. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Genoa. You will spend 1 night here for some well-deserved relaxation.

Prepare for a day full of family-friendly attractions, romantic experiences, and scenic views. When you’re ready, kick off your sightseeing adventure at Mura Di Lucca. This underrated historical landmark is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Piazza Napoleone, one of the city’s best highlights.

Next, check out San Michele In Foro, one of the most beloved places to see in Florence. This church is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Piazza Dell'anfiteatro. Wander around and soak in the visually striking atmosphere this public square offers. Then, head to Area Marina Protetta Di Portofino, a top-rated nature reserve that adds another dimension to your day.

When you’re done exploring for the day, you’ll drive to your hotel in Genoa. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Genoa. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Vivarelli, an iconic dining spot in Genoa. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Trattoria Ugo, a popular restaurant in Genoa. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of TAZZE PAZZE Specialty Coffee, a hidden gem nestled in Genoa. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Say good night to Genoa and look forward to another great day of your road trip in Italy!

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Day 8

Day 8

  • Genoa - Departure day
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  • piazza De Ferrari
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Day 8 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Genoa before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Piazza De Ferrari, a history-steeped public square before you head out.

Make the most of your final day in Italy by visiting Genoa’s iconic markets and shopping establishments in the buzzing Via XX Settembre. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Italy.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Genoa.

Treat yourself to a delicious dinner at Bar Festival, an excellent option for tonight's dining. Looking for something different? Il Marin offers a tantalizing alternative with its diverse menu. And don’t miss Ristorante da Cupido.

You’ll then say farewell to Genoa. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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