One-Week Italy Self-Drive Road Trip With Itinerary from Venice to Florence and Rome

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Explore the best of Italy on a 8-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Venice, Murano, Bologna, Florence, Siena, Rome, and Orvieto. This road trip itinerary in Italy seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Venice, 2 nights in Florence, and 2 nights in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Venice, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of Piazza San Marco.

As you hit the open road and drive through Venice, Murano, Bologna, Florence, Siena, Rome, and Orvieto, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Santa Maria della Salute
Bridge of SighsDoge's PalaceSt Mark's BasilicaPiazza San MarcoRialto BridgeMurano
Porta MaggiorePiazza Santo StefanoTwo TowersBologna CathedralPiazza MaggioreBasilica of San Domenico
Basilica of Santa Croce in FlorenceUffizi GalleryPonte Vecchiopiazza della SignoriaCathedral of Santa Maria del FioreGalleria dell'Accademia
Fortezza MediceaVista Panoramica de SienaSiena Cathedralpiazza del CampoPubblico Palace
ColosseumRoman ForumTrevi FountainPantheonPiazza NavonaSt Peter's Basilica
Well of St PatrickOrvieto CathedralOrvieto subterraneaTorre del Moro OrvietoPozzo della Cava
Palazzo Contarini del Bovolo

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Day 1

Day 1

  • Venice - Arrival day
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  • Santa Maria della Salute
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Say hello to Venice! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Venice for 2 nights before you continue your adventure!

Venice is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Santa Maria Della Salute, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Venice. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Venice, it's often a good idea to reserve a table in advance.

Dine in style at Bauer Hotel, a top recommendation for dinner tonight. Or, for a change of pace, L'Osteria Le Guglie boasts a menu that's sure to impress. Also, be sure to check out Corner Pub. Known as a local hotspot, it’s a great choice for tonight in Venice.

Unwind after your meal by stepping into Al Parlamento. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, The Caffe Rosso offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Adagio, another top-rated bar in the area.

Raise a toast to the start of your 8-day road trip in Italy!

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Day 2

Day 2

  • Venice
  • More

Drive 15 km, 42 min

  • Bridge of Sighs
  • Doge's Palace
  • St Mark's Basilica
  • Piazza San Marco
  • Rialto Bridge
  • Murano
  • More

On day 2 of your road trip, you’ll start and end your day in Venice, where you'll stay for 1 night more.

Start by visiting Bridge Of Sighs, a prime spot to begin your journey. This visually striking monument is sure to impress. Next on your list is Doge's Palace, another must-visit landmark and popular palace renowned for its enchanting features.

While exploring and sightseeing, take time to savor the culture of Venice by sampling some local delicacies. When you’re ready for more sightseeing, head to St Mark's Basilica. This history-steeped church is an essential place to visit for anyone looking for the full Venice experience. We also recommend visiting Piazza San Marco, an iconic public square. Nearby, you'll also find Rialto Bridge, ready to add charm to your journey. End your self-guided sightseeing tour with a stop at Murano and wrap up your day with its enchanting appeal.

When you’re done exploring for the day, you’ll return to Venice and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Venice. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Savor the flavors at Generator Venice, a top pick for dinner tonight. Alternatively, Nevodi beckons with its unique menu offerings. Also, consider Ristorante La Piazza. With its consistent customer satisfaction, it’s an excellent option for dining in Venice tonight.

After savoring a delicious meal, step into the vibrant nightlife at Il Mercante, where the evening is just getting started. In the same way, The Irish Pub Venezia offers a unique charm perfect for experiencing the local bar scene in Venice. Ai Stagneri is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Say good night to Venice and look forward to another great day of your road trip in Italy!

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Day 3

Day 3

  • Venice
  • Florence
  • More

Drive 274 km, 3 hours 55 min

  • Porta Maggiore
  • Piazza Santo Stefano
  • Two Towers
  • Bologna Cathedral
  • Piazza Maggiore
  • Basilica of San Domenico
  • More

Dive into day 3 of your remarkable road trip in Italy. Today you will explore Bologna, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Florence. You’ll stay here for 2 nights.

Savor the day by visiting some of the best places to see in Venice, including a monument, a public square, and a church. Start your adventure at Porta Maggiore. This curiosity-inducing monument is a must-visit for travelers looking for a unique holiday experience. Make your way to Piazza Santo Stefano located in Venice for another exciting encounter.

Next, immerse yourself in the setting of Two Towers. Its respected features will captivate you. After the monument, continue your tour of the city with a visit to Bologna Cathedral. Visitors usually appreciate the historic features of this church. Next up is Piazza Maggiore, a highly recommended public square. For a change of pace, head to Basilica Of San Domenico. As one of the most frequently visited attractions in Venice, this church is the perfect place to end your self-guided sightseeing tour.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at Ristorante Oliviero 1962, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Di Poneta Novoli, another top spot with a mouthwatering menu. You might also want to secure a reservation at Caffe San Firenze. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

Unwind after your meal by stepping into Manifattura. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Se·sto On Arno Rooftop Bar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Il Vinile, another top-rated bar in the area.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 4

Day 4

  • Florence
  • More

Drive 3 km, 50 min

  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • piazza della Signoria
  • Cathedral of Santa Maria del Fiore
  • Galleria dell'Accademia
  • More

Day 4 of your road trip across Italy promises a magnificent time exploring Florence. You have 1 night left in Florence. Take the opportunity to experience more of the best attractions and activities in the city.

Start by visiting Basilica Of Santa Croce In Florence, a prime spot to begin your journey. This instagrammable church is sure to impress. Next on your list is Uffizi Gallery, another must-visit landmark and impressive art gallery renowned for its romantic features.

While exploring and sightseeing, take time to savor the culture of Florence by sampling some local delicacies. When you’re ready for more sightseeing, head to Ponte Vecchio. This majestic historical landmark is an essential place to visit for anyone looking for the full Florence experience. We also recommend visiting Piazza Della Signoria, a widely recognized public square. Nearby, you'll also find Cathedral Of Santa Maria Del Fiore, ready to add charm to your journey. End your self-guided sightseeing tour with a stop at Galleria Dell'accademia and wrap up your day with its instagrammable appeal.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Make sure to reserve a table at Ditta Artigianale, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Trattoria Da Burde, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Casa Toscana, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Keep the evening going at Bar 50 Rosso, a great choice for enjoying the after-dinner hours with a drink. You could also go to Bitter Bar, which offers a similarly pleasant setting and great drinks. Another option is Archea Brewery, which provides an inviting environment for unwinding after a busy day out.

Say good night to Florence and look forward to another great day of your road trip in Italy!

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Day 5

Day 5

  • Florence
  • Rome
  • More

Drive 317 km, 4 hours 21 min

  • Fortezza Medicea
  • Vista Panoramica de Siena
  • Siena Cathedral
  • piazza del Campo
  • Pubblico Palace
  • More

Experience an unparalleled adventure on day 5 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Siena. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Rome. You will spend 2 nights here for some well-deserved relaxation.

Brace yourself for today’s incredible lineup of attractions in Florence, featuring family-friendly attractions, scenic views, and picturesque spots. Start at Fortezza Medicea (siena), an underrated monument in the city. Then, head to Vista Panoramica De Siena and soak in the ambiance of this eye-catching observation deck.

There are many interesting places to see in Florence, and when you are ready for more, go to Siena Cathedral. This is one of the city’s most well-known romantic spots of interest. After exploring the church, visit the famous Piazza Del Campo. Not far away, you'll also find Pubblico Palace. This palace is a culturally significant highlight in Florence.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at La Bottega Roma, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Pasta In Corso, another top spot with a mouthwatering menu. You might also want to secure a reservation at Trattoria Vecchia Roma. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Round off your dining experience by visiting La Botticella Of Poggi Giovanni, a prime location for a drink. Alternatively, explore the distinctive characteristics of Almalu Trastevere, a bar catering to every mood and preference. Bar Viminale Di Pepi Maurilio likewise offers a unique atmosphere, perfect for a memorable night out.

Raise your glass to another unforgettable day in Italy!

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Day 6

Day 6

  • Rome
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Drive 11 km, 1 hour 17 min

  • Colosseum
  • Roman Forum
  • Trevi Fountain
  • Pantheon
  • Piazza Navona
  • St Peter's Basilica
  • More

Greet day 6 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Rome for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Rome and Vatican City.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Rome allows for both. Start by heading to Colosseum. This iconic archeological site provides an insightful glimpse into the city's identity. Next, discover Roman Forum, a picture-perfect archeological site, promising a delightful encounter.

Continue your sightseeing with a visit to Trevi Fountain, an iconic monument. When you’re done, don’t forget to make a stop at the wondrous Pantheon. Round off your day at Piazza Navona, another gem in Rome with symbolic features to discover.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a delightful dinner at RomAntica, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Coso Ristorante? It's another excellent option with a diverse menu. Consider reserving a table at DEROMA - Farine Romane as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

After your meal, keep the night alive at a bar like Sant' Eustachio Caffè, known for its lively atmosphere. Yellowsquare Rome is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Caffè Portofino offers an excellent atmosphere for those looking to amp up the evening.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 7

Day 7

  • Rome
  • Venice
  • More

Drive 543 km, 6 hours 28 min

  • Well of St Patrick
  • Orvieto Cathedral
  • Orvieto subterranea
  • Torre del Moro Orvieto
  • Pozzo della Cava
  • More

Embark on another extraordinary experience on day 7 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Orvieto. At the end of the day, you will enjoy the comforts of a top-rated hotel in Venice, which will be your home away from home for 1 night.

Rome is brimming with adventures. Today’s wonderful stops include a monument, a church, a cave system, a cave and much more! Begin your sightseeing adventure at the well-known Well Of St. Patrick and allow yourself time to explore. Just a short distance away you'll find your next stop, Orvieto Cathedral, an inviting church that draws visitors from far and near.

Continue your journey to Orvieto Underground, one of the village’s most up-and-coming spots that you shouldn’t miss. Another great site to visit is the beloved Torre Del Moro Orvieto. When you're finished at the monument, Pozzo Della Cava awaits your visit. This cave is a photogenic highlight on today's itinerary.

When you’re done exploring for the day, you’ll drive to your hotel in Venice. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a fantastic dining experience at Osteria Alla Staffa, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Bistrot de Venise offers an enticing alternative with its varied menu. Additionally, Corte Sconta is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Venice.

Let the evening flow smoothly from dinner to drinks at Dolce Vita Venezia, a top-rated bar in the area. For other recommendations, Tarnowska's American Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Bar All'angolo offers a memorable night with diverse drink options and excellent service.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 8

Day 8

  • Venice - Departure day
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  • Palazzo Contarini del Bovolo
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Day 8 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Venice before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Palazzo Contarini Del Bovolo. This captivating palace is a popular place to see in the city.

Make the most of your final day in Italy by visiting Venice’s iconic markets and shopping establishments in the buzzing Calle Larga XXII Marzo. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Italy. Elevate your style with pieces from high-end retail stores.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Venice.

Dine in style at Cantina Do Spade, a top recommendation for dinner tonight. Or, for a change of pace, Trattoria Al Gazzettino boasts a menu that's sure to impress.

You’ll then say farewell to Venice. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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