12-Day Italy Self-Drive Road Trip With Itinerary from Florence traveling south to Siena, Rome, and Sorrento

Day 2 offers a multitude of experiences. You will stay in Florence for 2 nights more, offering you enough time to explore at a relaxed pace.

Florence is brimming with adventures. Today’s wonderful stops include a historical landmark, an art gallery, a palace, a church, a monument and much more! Begin your sightseeing adventure at the wondrous Ponte Vecchio and allow yourself time to explore. Just a short distance away you'll find your next stop, Uffizi Gallery, a historic art gallery that draws visitors from far and near.

Continue your journey to Palazzo Vecchio, one of the city’s most locally renowned spots that you shouldn’t miss. Another great site to visit is the top-rated Cathedral Of Santa Maria Del Fiore. When you're finished at the church, Giotto's Bell Tower awaits your visit. This monument is a visually striking highlight on today's itinerary. Last up is a church - the popular Basilica Of Santa Croce In Florence.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Treat yourself to a wonderful meal at Ditta Artigianale, a top-rated dining spot in Florence. If you're in the mood for something new, try Trattoria Da Burde, another premier location with a delectable menu. You might also want to book a table at Casa Toscana. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

After savoring a delicious meal, step into the vibrant nightlife at Bar 50 Rosso, where the evening is just getting started. In the same way, Bitter Bar offers a unique charm perfect for experiencing the local bar scene in Florence. Archea Brewery is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Savor another day of unforgettable experiences in Italy!

On day 3 of your road trip in Italy, you’ll start and end your day in Florence, but spend the day exploring what’s beyond the city. Since you will return to Florence for 1 night more, there’s no need to rush. Experience Pisa and Lucca to the fullest today with this curated day itinerary!

Set out on a day brimming with family-friendly attractions, scenic views, and picturesque spots. Start at the timeless Piazza Del Duomo, Pisa, a historic public square in Florence. Next, go to Pisa Cathedral.

After visiting Piazza Del Duomo, Pisa and Pisa Cathedral, have a stroll along Florence's streets and take in the local charm. Continue your sightseeing by heading to Leaning Tower Of Pisa. This breathtaking monument offers a unique experience. Mura Di Lucca is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Piazza Dell'anfiteatro, one of the most enchanting places to visit in Florence.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Enjoy a delicious meal at Ristorante Buca Mario, a highly-rated dining destination in Florence. If you're eager to try something different, consider Agricola Toscana, another top spot with a tantalizing menu. You might also want to secure a reservation at Eataly Firenze. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Florence this evening.

After savoring a delicious meal, step into the vibrant nightlife at Gosh*, where the evening is just getting started. In the same way, Antico Caffè Del Moro - Art Bar Firenze offers a unique charm perfect for experiencing the local bar scene in Florence. Quelo Bar is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Say good night to Florence and look forward to another great day of your road trip in Italy!

On day 4 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Siena. When you’re not sightseeing, take time to relax at your selected hotel in Siena, where you’ll be staying for 2 nights.

Today's adventure in Florence promises more breathtaking discoveries and enriching experiences! Begin at Fortezza Medicea (siena). This culturally significant monument is a highlight of any visit in the city. Then, enjoy Basilica Of San Domenico, another symbolic attraction that never fails to captivate visitors. Next, head over to Siena Cathedral, one of the city’s most popular attractions, known for its enchanting features.

If you’re looking for more, spend time soaking in the atmosphere of Pubblico Palace. This culturally significant palace is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Piazza Del Campo, an astonishing public square, and take a stroll around the area. If you want to extend your self-guided sightseeing tour, go check out Tower Of Mangia before you head back to your hotel.

At the end of the day, you will drive to Siena, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Siena. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Enoteca I Terzi, an iconic dining spot in Siena. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante Tar-Tufo, a popular restaurant in Siena. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Antica Trattoria Papei, a hidden gem nestled in Siena. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your meal, keep the night alive at a bar like Meet Life Cafè, known for its lively atmosphere. Maudit Pub is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Bar Impero Siena offers an excellent atmosphere for those looking to amp up the evening.

Head back to your accommodation in Siena and get some rest in preparation for another magical day of your road trip in Italy!

Greet day 5 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Siena for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in San Gimignano, Greve in Chianti, and Siena.

Today’s route brings fun adventures, breathtaking views, and picturesque spots. The first attraction of today is Porta San Giovanni. This frequently visited monument is a picture-perfect place to see in Siena. Continue your discovery at Piazza Del Duomo, an enchanting public square with stories to tell.

As you stroll around Siena, take in the distinct atmosphere and learn what makes this village so unique. Maximize your sightseeing with a visit to Palazzo Comunale, Pinacoteca, Torre Grossa. This up-and-coming museum offers a breathtaking encounter with Siena. Next, make your way to Parco Della Rocca to add another highlight to your day. After that, visit Castle Of Verrazzano, an often recommended castle that’s sure to impress. If you’re up for more, end your self-guided sightseeing tour at Porta Camollia, Siena, an increasingly popular monument in the village. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Siena.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Siena.

As dinnertime approaches, it's time to head out for a bite to eat in Siena. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Osteria Quattro Venti, an iconic dining spot in Siena. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Fischi per Fiaschi, a popular restaurant in Siena. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Osteria da Divo, a hidden gem nestled in Siena. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Keep the evening going at Charlie Mixology Bar Di Aldinucci Riccardo, a great choice for enjoying the after-dinner hours with a drink. You could also go to Bar Pinacoteca, which offers a similarly pleasant setting and great drinks. Another option is San Paolo Pub, which provides an inviting environment for unwinding after a busy day out.

Take some time to reflect on your day and savor another beautiful night in Italy.

Embark on another extraordinary experience on day 6 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Rome. At the end of the day, you will enjoy the comforts of a top-rated hotel in Rome, which will be your home away from home for 3 nights.

Today’s route brings fun adventures, scenic views, and photo-friendly spots. The first attraction of today is Colosseum. This world-famous archeological site is a breathtaking place to see in Siena. Continue your discovery at Roman Forum, a picture-perfect archeological site with stories to tell.

As you stroll around Siena, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Trevi Fountain. This wondrous monument offers a history-steeped encounter with Siena. Next, make your way to Pantheon to add another highlight to your day. After that, visit Piazza Navona, a wondrous public square that’s sure to impress. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Siena.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delightful dinner at La Bottega Roma, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Pasta In Corso? It's another excellent option with a diverse menu. Consider reserving a table at Trattoria Vecchia Roma as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

Round off your dining experience by visiting La Botticella Of Poggi Giovanni, a prime location for a drink. Alternatively, explore the distinctive characteristics of Almalu Trastevere, a bar catering to every mood and preference. Bar Viminale Di Pepi Maurilio likewise offers a unique atmosphere, perfect for a memorable night out.

Celebrate another amazing day of your road trip adventure in Italy!

At the end of the day, you'll drive back to Rome, where you'll stay for 2 nights more.

At the top of the list of things to do today is to explore Trastevere, a neighborhood that captures the true essence of Vatican City. Take your time to uncover its best sides and enjoy its proximity to many of the area’s best attractions.

Start your day at Vatican Museums. Then, wander over to Sistine Chapel. Nearby, you’ll also find St. Peter's Basilica.

Rome offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Piazza Di Spagna is a globally renowned spot in the city that will captivate you with its unique charm. When you’re done at the public square, don’t forget to check out the enchanting Spanish Steps. Take a moment to appreciate the fascinating details of this widely recognized public square.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a delightful dinner at RomAntica, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Coso Ristorante? It's another excellent option with a diverse menu. Consider reserving a table at DEROMA - Farine Romane as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

Round off your dining experience by visiting Sant' Eustachio Caffè, a prime location for a drink. Alternatively, explore the distinctive characteristics of Yellowsquare Rome, a bar catering to every mood and preference. Caffè Portofino likewise offers a unique atmosphere, perfect for a memorable night out.

Celebrate another amazing day of your road trip adventure in Italy!

Wake up to day 8 of your extraordinary road trip in Italy. With 1 night left in Rome, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Rome allows for both. Start by heading to Villa D'este. This captivating palace provides an insightful glimpse into the town's identity. Next, discover Hadrian's Villa, a culturally significant archeological site, promising a delightful encounter.

Continue your sightseeing with a visit to Circus Maximus, an interesting archeological site. When you’re done, don’t forget to make a stop at the notable Altare Della Patria. Not far away from the monument, you will find the romantic Castel Sant'angelo, perfect for a quick visit. Round off your day at Piazza Del Popolo, another gem in Rome with masterful features to discover.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a lovely dining experience at Hotel de Russie, a popular restaurant in Rome. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Rome at La Taverna Italiana, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated The Parrot Bar. It’s yet another ideal choice to enhance your time in Rome tonight.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, The Apartment Bar Roma stands out as an excellent choice for a post-dinner cocktail. Alternatively, Hotel Hassler Roma offers an ideal atmosphere to enjoy the pleasures of the night.

Savor another day of unforgettable experiences in Italy!

Experience an unparalleled adventure on day 9 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Sorrento and Amalfi. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Sorrento. You will spend 2 nights here for some well-deserved relaxation.

Enjoy the perfect balance of relaxation and exploration in Rome today. One of the most beloved attractions included on the itinerary is Basilica Sant'antonino. This heritage-rich church will help you start your sightseeing on top. Then, take a leisurely stroll to Villa Comunale Di Sorrento and learn what makes this eye-catching park unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the frequently visited Cathedral Of Saints Philip And James. After exploring the church, head to Parco Di Villa Fiorentino. This curiosity-inducing park is a highlight in Rome. Lastly, don’t forget to check out the underrated Saint Andrew's Fountain Amalfi. Enjoy exploring this incredible monument at your own pace.

When you’re done exploring for the day, you’ll drive to your hotel in Sorrento. Check in and spend some time relaxing before you head out to tour the town.

After a day of adventure, treat yourself to an exquisite dinner at one of Sorrento's best restaurants.

Make sure to reserve a table at Frankie's Pizza Bar Sorrento Brunch & Vegan, an iconic dining spot in Sorrento. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bougainvillea, a popular restaurant in Sorrento. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Banana Split, a hidden gem nestled in Sorrento. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Extend your evening after a delightful meal by visiting Leone Rosso Café, which offers the perfect atmosphere for a night out. Moreover, Hotel Antiche Mura Sorrento is another popular option for a drink or two.

Say good night to Sorrento and look forward to another great day of your road trip in Italy!

On day 10 of your road trip, you’ll start and end your day in Sorrento, where you'll stay for 1 night more.

Today’s itinerary in Sorrento covers several incredible sights, including an archeological site, an observation deck, a church, a beach and much more! Start your adventure at Archaeological Park Of Pompeii. This captivating archeological site is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the culturally significant wonders of Amphitheatre Of Pompeii, a must-see archeological site in the town.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Viewpoint.8-amalfi Dr. This up-and-coming observation deck offers an enriching experience. For a change of pace, head to Chiesa Di Santa Maria Assunta, where you can take in enchanting features. Conclude your self-guided sightseeing tour with a visit to Spiaggia Di Positano Marina Grande. These sights offer a fulfilling end to a perfect day.

When you’re done exploring for the day, you’ll return to Sorrento and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Sorrento. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a wonderful meal at Fuoro51, a top-rated dining spot in Sorrento. If you're in the mood for something new, try Hotel Bellevue Syrene, another premier location with a delectable menu. You might also want to book a table at Hotel Villa Fiorita. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Sorrento.

Relax and recharge in preparation for another adventurous day in Italy!

On day 11 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Orvieto. In the evening, you’ll end up in Florence, where you will stay for 1 night.

Get ready for an exciting day in Sorrento. Today’s sightseeing agenda includes a monument, a church, a cave system, a cave and much more! Begin your adventure at Well Of St. Patrick. This is a notable monument you should not miss. Another must-see is Orvieto Cathedral, a locally renowned church in Sorrento.

When you’re ready for the next sight, head to Orvieto Underground. From there, take a leisurely stroll to Torre Del Moro Orvieto, another of the village’s curiosity-inducing attractions. We recommend continuing your self-guided tour at Pozzo Della Cava, a heritage-rich place of interest in the village.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a delicious meal at Tijuana, a highly-rated dining destination in Florence. If you're eager to try something different, consider Djària - American Bar, another top spot with a tantalizing menu. You might also want to secure a reservation at The Florence Irish Pub. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Florence this evening.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!