5-Day Italy Self-Drive Road Trip With Itinerary from Genoa to Portofino and Pisa

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Photo of Sand beach in Camogli by Genoa, Italy.
Photo of Piazza De Ferrari main square in Genoa Italy.
Photo of Courtyard of Palazzo Reale in Genoa, Italy.
Photo of View of Genoa at sunset from "Spianata Castelletto", Italy.
Photo of Sestri Levante - Paradise Bay of Silence with its boats and its lovely beach. Beautiful coast at Province of Genoa in Liguria, Italy - Europe.
Photo of Genoa, Liguria, Italy downtown city skyline from above at dusk.
Photo of The Aquarium of Genoa is the largest aquarium in Italy. Located in the old harbor area of Genova.
Photo of Genoa port from above at night.
Photo of Palace of St George (Palazzo San Giorgio), Genoa, Italy.
Photo of Genova Brignole Railway Station in the evening.
Photo of View of Bogliasco. Bogliasco is a ancient fishing village in Italy, Genoa, Liguria. Mediterranean Sea, sandy beach and architecture of Bogliasco town.
Photo of Beach with tourists in San Fruttuoso bay with the ancient Abbey (San Fruttuoso di Capodimonte), X-XI century, and Andrea Doria tower. Portofino and Camogli, Genoa province, Liguria, Italy, Europe.
Photo of View of Pieve Ligure and on Sori on the background, italian towns of ligurian riviera, Genoa (Genova) province, Italy.
photo of view of Bogliasco, Genoa, Italy town skyline on the Mediterranean sea at sunset.
Photo of Portofino in Italy by Pascvii
Aerial view at tower of Pisa in Italy on a sunny day.
Tourist female in Pisa, Arno river, lamp and buildings reflection. Lungarno view.santa maria della spina
Blue hour twilight with Duomo and world famous Leaning Tower travel background in Tuscany.
Landscape with Pisa old town and Arno river, Tuscany, Italy.
 Tourists and locals enjoy a sunny day on the Corso Italia, the main shopping and dining street through the Tuscan city of Pisa, Italy.
Gothic church of Santa Maria della Spina, built around 1230 in the Pisan Gothic style.
Building in botanical garden of Pisa (Orto botanico di Pisa) in Italy
Photo of Tourists at the Primatial Metropolitan Cathedral of the Assumption of Mary in Pisa.
Carriage with horse in front of the leaning tower of Pisa
San Miniato, Pisa, Tuscany, Italy: the ancient catholic theological seminary in the picturesque old town.
Piazza Vittorio Emanuele square in the centre of Pisa city in Tuscany, Italy
Beautiful building of University on Piazza dei Cavalieri (Palazzo della Carovana) decorated with sgraffiti and sculptures of Grand Dukes of Tuscany. The statue depicts Cosimo I de' Medici. Pisa, Italy
The Cittadella Nuova now called the Giardino di Scotto or Giardino Scotto is an old fortress in Pisa, Italy
Piazza dei Cavalieri, Palazzo della Carovana, Palazzo dell'Orologio in Pisa, Italy. Architecture and landmark of Pisa. Cityscape of Pisa
Pisa, Italy. Leaning Tower of Pisa. Panoramic view in the evening. Aerial view
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Escape the ordinary with this exciting 5-day road trip through Italy. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Genoa, 1 night in Portofino, and 1 night in Pisa. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Genoa, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Ponte Vecchio and Leaning Tower Of Pisa are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Piazza Del Duomo, Pisa, learn more about the unique Uffizi Gallery, and immerse yourself in the vibrant atmosphere of Aquarium Of Genoa.

As you hit the open road and drive through Genoa, Portofino, Corniglia, Pisa, Florence, and Lucca, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Aquarium of Genoa
piazza De FerrariGenoa CathedralDoge's PalaceVia GaribaldiGalata - Museo del mareArea Marina Protetta di Portofino
Cinque Terre National ParkLeaning Tower of PisaPiazza del Duomo, Pisa
Basilica of Santa Croce in FlorenceUffizi GalleryPonte VecchioWalls of Lucca
porto antico

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Day 1

Day 1

  • Genoa - Arrival day
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  • Aquarium of Genoa
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Your road trip adventure in Italy begins as soon as you reach Genoa and pick up your car. You’ll stay in Genoa for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Genoa is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Aquarium Of Genoa, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Genoa. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Genoa, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at 7 Sensi cucina decontaminata, a highly-rated dining destination in Genoa. If you're eager to try something different, consider Alla Lunga Ristorante, another top spot with a tantalizing menu. You might also want to secure a reservation at Grand Hotel Savoia. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Genoa this evening.

Continue your lively evening at Scurreria Beer & Bagel, a perfect place for winding down or revving up the night, depending on which mood you’re in. La Lepre is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Bar Pisacane Iii ensures a night out tailored to your taste.

Raise a toast to the start of your 5-day road trip in Italy!

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Day 2

Day 2

  • Genoa
  • Portofino
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Drive 58 km, 1 hour 51 min

  • piazza De Ferrari
  • Genoa Cathedral
  • Doge's Palace
  • Via Garibaldi
  • Galata - Museo del mare
  • Area Marina Protetta di Portofino
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On day 2 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Genoa and San Fruttuoso di Camogli. When you’re not sightseeing, take time to relax at your selected hotel in Portofino, where you’ll be staying for 1 night.

Enjoy the perfect balance of relaxation and exploration in Genoa today. One of the most captivating attractions included on the itinerary is Piazza De Ferrari. This majestic public square will help you start your sightseeing on top. Then, take a leisurely stroll to Genoa Cathedral and learn what makes this photogenic church unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the locally appreciated Doge's Palace. After exploring the museum, head to Via Garibaldi. This increasingly popular street is a highlight in Genoa. As your day continues, stop by Galata Museo Del Mare (complex), known for its eye-catching features. Lastly, don’t forget to check out the often recommended Area Marina Protetta Di Portofino. Enjoy exploring this incredible nature reserve at your own pace.

When you’re done exploring for the day, you’ll drive to your hotel in Portofino. Check in and spend some time relaxing before you head out to tour the village.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Portofino. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Don’t miss out on dining at Trattoria Concordia, a top-rated dining destination in Portofino. If you're in the mood to try something new, consider Ristorante Da Ö Batti Portofino - Ristorante Da Ö Batti, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante Puny. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Portofino this evening.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 3

Day 3

  • Portofino
  • Pisa
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Drive 185 km, 3 hours 33 min

  • Cinque Terre National Park
  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
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Dive into day 3 of your remarkable road trip in Italy. Today you will explore Corniglia and Pisa, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Pisa. You’ll stay here for 1 night.

Portofino is brimming with adventures. Today’s wonderful stops include a national park, a monument, and a public square. Begin your sightseeing adventure at the well-known Cinque Terre National Park and allow yourself time to explore. Just a short distance away you'll find your next stop, Leaning Tower Of Pisa, a picture-perfect monument that draws visitors from far and near.

Continue your journey to Piazza Del Duomo, Pisa, one of the village’s most timeless spots that you shouldn’t miss.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Pisa. Pisa offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Pisa. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Anima di Grano Pizzeria Napoletana Pisa Italy, a top-rated dining destination in Pisa. If you're in the mood to try something new, consider il Mercante, another top spot with a mouthwatering menu. You might also want to secure a reservation at La Ghiotteria. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Pisa this evening.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Jeffer Cocktails & Friends stands out as an excellent choice for a post-dinner cocktail. Alternatively, Le Parisien Wine Bar offers an ideal atmosphere to enjoy the pleasures of the night. Las Volta Cocktailbar is also a great option that provides a perfect setting for a relaxing evening.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 4

Day 4

  • Pisa
  • Genoa
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Drive 323 km, 4 hours 28 min

  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • Walls of Lucca
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On day 4 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Florence and Lucca. In the evening, you’ll end up in Genoa, where you will stay for 1 night.

Today’s route brings fun adventures, picturesque spots, and historic treasures. The first attraction of today is Basilica Of Santa Croce In Florence. This notable church is a culturally significant place to see in Pisa. Continue your discovery at Uffizi Gallery, a picture-perfect art gallery with stories to tell.

As you stroll around Pisa, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Ponte Vecchio. This world-famous historical landmark offers a romantic encounter with Pisa. Next, make your way to Mura Di Lucca to add another highlight to your day. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Pisa.

At the end of the day, you will drive to Genoa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Genoa. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely dining experience at Zeffirino, a popular restaurant in Genoa. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Genoa at Trattoria Vegia Zena, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Trattoria delle Grazie. It’s yet another ideal choice to enhance your time in Genoa tonight.

Savor another day of unforgettable experiences in Italy!

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Day 5

Day 5

  • Genoa - Departure day
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  • porto antico
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Day 5 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Genoa before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Porto Antico. This notable public square is a popular place to see in the city.

On your last day in Italy, take time to indulge in shopping at Genoa’s popular marketplace, Porto Antico. Look for keepsakes or souvenirs to remind you of your trip.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Genoa.

You’ll then say farewell to Genoa. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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