5-Day Italy Road Trip from Perugia traveling north to Florence

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Explore the best of Italy on a 5-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Perugia, Castiglione del Lago, Magione, Florence, Bologna, and Siena. This road trip itinerary in Italy seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Perugia, and 2 nights in Florence. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Perugia, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Ponte Vecchio and Piazzale Michelangelo are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Perugia, Castiglione del Lago, Magione, Florence, Bologna, and Siena, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Day 1

Day 1 – Perugia - arrival day

  • Perugia - Arrival day
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  • Etruscan Arch
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Say hello to Perugia! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Perugia for 1 night before you continue your adventure!

Perugia is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Etruscan Arch or taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Perugia. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat in Perugia. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Dine in style at Ristorante Settimo Sigillo, a top recommendation for dinner tonight. Or, for a change of pace, Bar Pellas boasts a menu that's sure to impress. Also, be sure to check out La Taverna. Known as a local hotspot, it’s a great choice for tonight in Perugia.

Continue your lively evening at Tommi Bar, a perfect place for winding down or revving up the night, depending on which mood you’re in. Valentina is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Caffe Dal Perugino ensures a night out tailored to your taste.

Raise a toast to the start of your 5-day road trip in Italy!

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Day 2

Day 2 – Perugia, Castiglione del Lago, Magione, and Florence

  • Florence
  • Perugia
  • Castiglione del Lago
  • Magione
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Drive 191 km, 3 hours 50 min

  • Carducci Gardens
  • Rocca Paolina
  • Frontone Gardens
  • Parco Regionale del Lago Trasimeno
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Embark on another extraordinary experience on day 2 of your road trip in Italy. Today, you will make 3 stops and experience some of the highlights of Perugia, Castiglione del Lago, and Magione. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 2 nights.

Take the opportunity to see Carducci Gardens. This attraction has an average rating of 4.5 out of 5 stars from 1,768 visitors.

Rocca Paolina is another sightseeing hotspot in the area. This rocca has been rated an average of 4.7 out of 5 stars by 7,128 travelers.

Perugia is also the home of Frontone Gardens. Around 1,722 people have rated this garden an average of 4.4 out of 5 stars.

Embrace the thrill of the open road as you wave goodbye to Perugia and set your GPS to Castiglione del Lago. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 40 min. Upon reaching Castiglione del Lago, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Make Palazzo Ducale (castiglione Del Lago) one of your first sightseeing stops in Castiglione del Lago. Rated an average of 4.4 out of 5 stars by 1,484 travelers, a visit to this local attraction makes for a great introduction to the area.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Have a memorable dining experience in Florence by booking a table at Enoteca Pinchiorri, renowned as a 3-star Michelin restaurant presenting an exceptional italian contemporary menu. For a different culinary experience in Florence, Santa Elisabetta shines as one of the top destinations, known for its delicious creative, and mediterranean cuisine. This 2-star Michelin-awardee earns consistently high praises from previous guests, making it a must-visit addition to your holiday experience. If you're looking for an alternative, Gucci Osteria da Massimo Bottura is known as a top local spot for its delicious italian contemporary, and international cuisine in Florence. This 1-star Michelin awardee is a highly recommended choice for an unforgettable meal.

After enjoying a fulfilling meal, continue your evening at Manifattura, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Se·sto On Arno Rooftop Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Archea Brewery provides an excellent environment for a relaxed and enjoyable evening.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 3

Day 3 – Florence, and Bologna

  • Florence
  • Bologna
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Drive 222 km, 3 hours 45 min

  • Two Towers
  • Piazza Maggiore
  • Cathedral of Santa Maria del Fiore
  • piazzale Michelangelo
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Wake up to day 3 of your extraordinary road trip in Italy. With 1 night left in Florence, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Kick off the day at Central Market, a top pick for today’s sightseeing. This sightseeing destination is rated an average of 4.4 out of 5 stars in 43,100 reviews.

Today is also your chance to visit Cathedral Of Santa Maria Del Fiore. Cathedral Of Santa Maria Del Fiore is a church with an average rating of 4.8 out of 5 stars from 76,359 reviews.

Piazzale Michelangelo is another top attraction we highly recommend you visit today. This square is rated an average of 4.8 out of 5 stars by 77,744 visitors.

Continue your road trip and head to your next destination, Bologna. This car ride takes around 1 hour 30 min.

When you're ready to see some sights, Two Towers is a great place to start. This tower is rated an average of 4.7 out of 5 stars by 25,975 visitors.

Another popular attraction you can visit today is Piazza Maggiore. This square has an average rating of 4.7 out of 5 stars from 64,523 travelers.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Trattoria Da Burde, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Ristorante Buca Mario, another top spot with a mouthwatering menu. You might also want to secure a reservation at Eataly Firenze. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Florence this evening.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 4

Day 4 – Florence, Siena, and Perugia

  • Perugia
  • Florence
  • Siena
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Drive 187 km, 2 hours 52 min

  • piazza della Signoria
  • Ponte Vecchio
  • Uffizi Gallery
  • Basilica of Santa Croce in Florence
  • piazza del Campo
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On day 4 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Florence, and Siena. In the evening, you’ll end up in Perugia, where you will stay for 1 night.

Kick off the day at Piazza Della Signoria, a top pick for today’s sightseeing. This square is rated an average of 4.8 out of 5 stars in 66,956 reviews.

Today is also your chance to visit Ponte Vecchio. Ponte Vecchio is a deck arch bridge with an average rating of 4.7 out of 5 stars from 118,099 reviews.

Uffizi Gallery is another top attraction we highly recommend you visit today. This national museum is rated an average of 4.7 out of 5 stars by 61,794 visitors. In a single year, this national museum hosts approximately 2,011,219 visitors.

Beyond the attractions mentioned above, you also have the opportunity to visit Basilica Of Santa Croce In Florence. This church is rated an average of 4.7 out of 5 stars by 28,544 visitors.

Set your GPS to Siena and hit the road. Expect a journey of approximately 1 hour 9 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Siena beckons with new experiences!

When you’re ready for some sightseeing, make your way to Piazza Del Campo. This much-appreciated square is rated 4.8 out of 5 stars in 64,175 reviews.

At the end of the day, you will drive to Perugia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Perugia. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Ristorante del Sole, a top-rated dining destination in Perugia. If you're in the mood to try something new, consider Al Mangiar Bene, another top spot with a mouthwatering menu. You might also want to secure a reservation at Elfo Pub Perugia. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Perugia this evening.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Caffè Fortebraccio, known for its inviting atmosphere. Caffe Del Banco is another great option if you’re looking for a place to get the night started. Similarly, Dempsey's Perugia provides a great setting to enjoy the night away.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 5

Day 5 – Perugia - departure day

  • Perugia - Departure day
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  • Piazza IV Novembre
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Day 5 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Perugia before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Make the most of your final day in Italy by visiting Perugia’s iconic markets and shopping establishments. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Italy.

Start your sightseeing with a visit to Piazza Iv Novembre. This square is a popular stop on travelers’ itineraries in Perugia, with an average rating of 4.6 out of 5 stars by 9,189 visitors.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Perugia.

Dine in style at Sangallo Palace Hotel, a top recommendation for dinner tonight. Or, for a change of pace, Osteria a Priori boasts a menu that's sure to impress.

You’ll then say farewell to Perugia. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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